# US 12,005,254 B2 · Electrical field usage in cochleas

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- Number: US 12,005,254 B2
- Document ID: US12005254B2
- Status: Granted
- Kind: B2
- Application number: 16/980,498
- Filed: 2019-03-12
- Published: 2021-01-28
- Granted: 2024-06-11
- Earliest claimed: 2018-03-13
- Assignees: Cochlear Limited
- Applicants: Cochlear Limited
- Inventors: Ryan Orin Melman
- Web page: https://patentgrep.com/patent/US12005254B2

## CPC

- A61N 1/36039: {fitting procedures}
- A61N 1/0541: {Cochlear electrodes}
- A61N 1/36038: {Cochlear stimulation}
- A61N 1/37229: {Shape or location of the implanted or external antenna}
- H04R 25/30: {Monitoring or testing of hearing aids, e.g. functioning, settings, battery power}
- H04R 2225/025: In the ear hearing aids [ITE] hearing aids
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)
- H04R: LOUDSPEAKERS, MICROPHONES, GRAMOPHONE PICK-UPS OR LIKE ACOUSTIC ELECTROMECHANICAL TRANSDUCERS; ELECTRIC HEARING AIDS; PUBLIC ADDRESS SYSTEMS (producing sounds with frequency not determined by supply frequency G10K)

## Abstract

A method including causing current to flow from a first electrode of an intra-cochlea electrode array to a second electrode of the intra-cochlea electrode array at a plurality of temporal locations, measuring, at a third electrode and a fourth electrode of the intra-cochlea electrode array, a voltage induced by the flowing current at the plurality of temporal locations and determining that a change between the voltage measurements at the third electrode and the fourth electrode has occurred from the first temporal location to the second temporal location.

## Claims

### Claim 1

A method comprising:
measuring a voltage, induced by an electric field, at a plurality of intra-cochlea electrodes located in a cochlea, wherein the voltages are measured relative to a common reference electrode separate from the plurality of intra-cochlea electrodes where the measurements are taken;
monitoring the relative magnitude of the measured voltages over time; and
detecting a voltage change across the plurality of intra-cochlea electrodes based on the monitored relative magnitude that is representative of a voltage change at the reference electrode.

### Claim 2 (depends on 1)

The method of claim 1, wherein the electric field comprises an electric dipole formed by stimulating between two intra-cochlea electrodes in the cochlea.

### Claim 3 (depends on 2)

The method of claim 2, wherein the reference electrode is disposed between the two stimulating intra-cochlea electrodes.

### Claim 4 (depends on 1)

The method of claim 1, comprising:
sourcing current at a first intra-cochlea electrode, and sinking current at a second intra-cochlea electrode, to create the electric field.

### Claim 5 (depends on 1)

The method of claim 1, wherein the change in voltage occurs simultaneously at respective electrodes of the plurality of intra-cochlea electrodes.

### Claim 6 (depends on 1)

The method of claim 1, wherein the plurality of electrodes includes at least 10 electrodes, and wherein the change in voltage occurs simultaneously at the respective electrodes of the plurality of intra-cochlea electrodes.

### Claim 7 (depends on 1)

The method of claim 1, further comprising:
inserting an electrode array into the cochlea while measuring the voltage at the plurality of electrodes; and
halting insertion upon the detection of the voltage change, wherein
the change in voltage occurs simultaneously at all electrodes in the cochlea where measurements are taken and occurs over an insertion distance of less than 3 mm.

### Claim 8 (depends on 1)

The method of claim 1, wherein the change in voltage is the same at respective electrodes of the plurality of intra-cochlea electrodes.

### Claim 9 (depends on 1)

The method of claim 1, wherein the voltage change at the reference electrode impacts all voltage measurements at the plurality of electrodes equally.

### Claim 10 (depends on 1)

The method of claim 1, wherein the plurality of electrodes include at least 6 electrodes, and wherein the voltage change at the reference electrode impacts all voltage measurements at the plurality of electrodes equally.

### Claim 11 (depends on 1)

The method of claim 1, wherein the voltage change is due to compression of an electrical field around an apical portion of a cochlea electrode array of which the plurality of intra-cochlea electrodes are a part.

### Claim 12 (depends on 1)

The method of claim 1, wherein the plurality of electrodes includes at least 10 electrodes, and wherein the voltage change at the reference electrode impacts all voltage measurements at the plurality of electrodes equally, which change occurs simultaneously at the at least 10 respective electrodes of the plurality of intra-cochlea electrodes.

### Claim 13 (depends on 1)

The method of claim 1, wherein:
the actions of measuring a voltage, monitoring the relative magnitude and detecting the voltage are executed during a surgery implanting the intra-cochlea electrodes in the cochlea.

### Claim 14 (depends on 1)

The method of claim 1, wherein:
the action of measuring the voltage and the action of monitoring the relative magnitude and the action of detecting the voltage change are all executed while the intra-cochlear electrodes are being advanced in the cochlea.

### Claim 15 (depends on 1)

The method of claim 1, further comprising:
determining that there is a constriction in the cochlea based on the detected voltage change.

### Claim 16 (depends on 1)

The method of claim 1, wherein the plurality of intra-cochlea electrodes located in the cochlea include at least four electrodes, and wherein the at least four electrodes are disposed symmetrically about the common reference electrode.

### Claim 17 (depends on 1)

The method of claim 1, wherein:
the method further includes automatically providing an instruction to a surgeon implanting the intra-cochlea electrodes based on the detected voltage change.

### Claim 18 (depends on 1)

The method of claim 1, further comprising:
during a first temporal period, pushing an electrode array into the cochlea, wherein the electrode array includes the intra-cochlea electrodes located in the cochlea; and
during a second temporal period after the first temporal period, halting the pushing of the electrode array into the cochlea upon detecting the voltage change.

### Claim 19 (depends on 1)

The method of claim 1, further comprising:
determining a biomarker based on the detected voltage change.

### Claim 20 (depends on 1)

The method of claim 1, wherein:
the detected voltage change is due to a narrowing of the cochlea.
