Vessel compression with hemodynamic wave reflection to control vascular wave dynamics and enhance blood flow

A system configured to be at least partially implanted in mammal along an aorta, the system comprising:

• an inelastic member comprising a biocompatible material, the inelastic member configured to surround at least a portion of an outer surface of an aorta at a first location along the aorta;
• and
• a pinching member comprising a second biocompatible material, the pinching member configured to surround at least a second portion the outer surface of the aorta at a second location along the aorta, wherein the pinching member further comprises an actuator configured to actuate compression of the aorta and a control unit configured to generate an activation signal at an activation rate and transmit the activation signal at the activation rate to the actuator,
• wherein the actuator is configured to receive the activation signal at the activation rate and in response to the activation signal, repeatedly compress the aorta at the second location at the activation rate to pump fluid within the aorta in a desired pumping direction, and
• wherein the actuator is further configured to receive the activation signal at the activation rate during both a systolic period and a diastolic period of a cardiac cycle of a heart of the mammal and in response to the activation signal, repeatedly compress the aorta at the second location at the activation rate during both the systolic period and the diastolic period of the cardiac cycle of a heart of the mammal.