# US 12,005,174 B2 · Automatic priming and scheduling for dialysis systems

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- Number: US 12,005,174 B2
- Document ID: US12005174B2
- Status: Granted
- Kind: B2
- Application number: 16/009,810
- Filed: 2018-06-15
- Published: 2019-12-19
- Granted: 2024-06-11
- Earliest claimed: 2018-06-15
- Assignees: Fresenius Medical Care Holdings, Inc.
- Applicants: Fresenius Medical Care Holdings, Inc.
- Inventors: Martin Joseph Crnkovich; David Yuds; Fei Wang; Haiyong Wang
- Web page: https://patentgrep.com/patent/US12005174B2

## CPC

- A61M 1/16: with membranes
- A61M 1/3644: {Mode of operation}
- A61M 1/34: Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M 1/3643: {Priming, rinsing before or after use}
- A61M 1/3647: {with recirculation of the priming solution}
- A61M 1/365: {through membranes, e.g. by inverted trans-membrane pressure [TMP]}
- G16H 40/63: for local operation
- A61M 39/28: Clamping means for squeezing flexible tubes, e.g. roller clamps {(tube strippers A61M1/83)}
- A61M 2205/15: Detection of leaks
- A61M 2205/18: with alarm
- A61M 2205/3306: Optical measuring means
- A61M 2205/3317: Electromagnetic, inductive or dielectric measuring means
- A61M 2205/3331: Pressure; Flow
- A61M 2205/3334: Measuring or controlling the flow rate
- A61M 2205/3368: Temperature
- A61M 2205/3389: Continuous level detection (A61M2205/3393 takes precedence)
- A61M 2205/502: User interfaces, e.g. screens or keyboards
- A61M 2205/505: Touch-screens; Virtual keyboard or keypads; Virtual buttons; Soft keys; Mouse touches
- A61M 2205/581: by audible feedback
- A61M 2205/582: by tactile feedback
- A61M 2205/583: by visual feedback
- A61M 2205/584: having a color code
- A61M 2205/587: Lighting arrangements
- A61M 2205/702: automatically during use
- A61M 2205/8206: battery-operated
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}
- G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA

## Abstract

A method including automatically performing at least one integrity test on a dialysis machine after powering on the dialysis machine, wherein the at least one integrity test is selected from the group consisting of a battery test, a dialysate conductivity test, and a dialysate temperature test. The method also includes presenting, on a display of the dialysis machine, a first set of instructions for priming the dialysis machine after completing the at least one integrity test.

## Claims

### Claim 1

A method of operating a dialysis machine, the method comprising:
automatically emitting: (a) an alert comprising a visual notification on a user interface of the dialysis machine and (b) auditory alerts, to warn personnel in the vicinity of the dialysis machine that the dialysis machine is about to be automatically powered on, wherein the visual notification comprises displaying: (i) a countdown of an amount of time until the dialysis machine will be automatically powered on and (ii) an abort option button that an operator may select to abort the dialysis machine being automatically powered on;
in response to the countdown of the amount of time becoming close to expiring, increasing a frequency of the auditory alerts or a length of the auditory alerts;
in response to the countdown of the amount of time running down to expiration, automatically powering on the dialysis machine;
in response to the dialysis machine becoming powered on, automatically beginning and performing at least one integrity test on the dialysis machine, wherein the dialysis machine is programmed to automatically begin and perform the at least one integrity test in response to becoming powered on, and wherein the at least one integrity test is selected from the group consisting of a battery test, a dialysate conductivity test, and a dialysate temperature test; and
presenting, on a display of the dialysis machine, a first set of instructions for priming the dialysis machine after completing the at least one integrity test.

### Claim 2 (depends on 1)

The method of claim 1, comprising presenting, on the display, an instruction of the first set of instructions comprising flowing, using gravity, priming fluid from a fluid source through an arterial blood line set.

### Claim 3 (depends on 2)

The method of claim 2, comprising presenting, on the display, an instruction of the first set of instructions comprising closing an end of the arterial blood line set and pumping the priming fluid through a dialyzer to prime the dialyzer.

### Claim 4 (depends on 2)

The method of claim 2, comprising presenting, on the display, an instruction of the first set of instructions comprising priming a dialysate side of a dialyzer of the dialysis machine prior to priming the arterial blood line set.

### Claim 5 (depends on 1)

The method of claim 1, comprising presenting, on the display of the dialysis machine, a second set of instructions for priming the dialysis machine upon completion of the first set of instructions.

### Claim 6 (depends on 5)

The method of claim 5, wherein completion of the first set of instructions comprises running a predetermined volume of fluid through a blood pump.

### Claim 7 (depends on 5)

The method of claim 5, wherein the second set of instructions is a set of instructions for a recirculation portion of an automatic priming procedure, wherein the second set of instructions instructs a user to connect the arterial blood line set to a venous blood line set.

### Claim 8 (depends on 7)

The method of claim 7, wherein one instruction in the second set of instructions instructs a user to rotate a dialyzer.

### Claim 9 (depends on 7)

The method of claim 7, comprising performing at least one functionality test during the recirculation portion of the automatic priming procedure, wherein the at least one functionality test is selected from the group consisting of a positive pressure test, a negative pressure test, an optical detection test, a blood leak detection test, a level detection test, a transmembrane pressure test, a venous pressure test, and an arterial pressure test.

### Claim 10 (depends on 7)

The method of claim 7, wherein the first set of instructions is displayed on a first screen, wherein the second set of instructions is displayed on a second screen, the second screen replacing the first screen when the first set of instructions is completed, and wherein at least one of the first screen and the second screen comprises a progress bar for indicating progress of the priming process.

### Claim 11 (depends on 9)

The method of claim 9, wherein performing at least one functionality test comprises:
measuring at least one parameter associated with the at least one functionality test;
comparing, by a controller, the at least one parameter to an expected operating range for the at least one parameter;
if the at least one parameter is outside of the expected operating range, returning an error message on the display; and
if the at least one parameter is within the expected operating range, indicating, on the display, that the at least one functionality test has been passed, wherein the error message comprises a description of a problem with at least one component of the dialysis machine.

### Claim 12 (depends on 1)

The method of claim 1, comprising presenting, on the display, a graphical representation of the dialysis machine, wherein the graphical representation of the dialysis machine and the first set of instructions include labels indicating that a step in the first set of instructions including the labels should be performed on a component of the dialysis machine including the labels.

### Claim 13 (depends on 1)

The method of claim 1, further comprising automatically powering on the dialysis machine at a pre-set time on a selected day.

### Claim 14 (depends on 1)

The method of claim 1, wherein the alert further comprises a vibrational alert.

### Claim 15 (depends on 1)

The method of claim 1, wherein the visual notification further comprises one or more blinking lights located at a top of the dialysis machine.

### Claim 16 (depends on 1)

The method of claim 1, wherein the amount of time is at least 10 seconds.