# US 12,005,155 B2 · High-modulus alloy for medical devices

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- Number: US 12,005,155 B2
- Document ID: US12005155B2
- Status: Granted
- Kind: B2
- Application number: 17/113,635
- Filed: 2020-12-07
- Published: 2021-07-22
- Granted: 2024-06-11
- Earliest claimed: 2020-01-22
- Assignees: Warsaw Orthopedic, Inc.
- Applicants: Warsaw Orthopedic, Inc.
- Inventors: James Davidson; William Rezach; Rodney Ballard
- Web page: https://patentgrep.com/patent/US12005155B2

## CPC

- A61L 27/047: {Other specific metals or alloys not covered by A61L27/042 - A61L27/045 or A61L27/06}
- A61L 27/50: Materials characterised by their function or physical properties {, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials}
- A61L 31/022: {Metals or alloys}
- A61L 31/14: Materials characterised by their function or physical properties {, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials}
- C22C 27/00: Alloys based on rhenium or a refractory metal not mentioned in groups C22C14/00 or C22C16/00
- C22C 27/04: Alloys based on tungsten or molybdenum
- A61L 2430/12: for dental implants or prostheses
- A61L 2430/22: for reconstruction of hollow organs, e.g. bladder, esophagus, urether, uterus
- A61L 2430/38: for reconstruction of the spine, vertebrae or intervertebral discs
- A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K)
- C22C: ALLOYS (treatment of alloys C21D, C22F)

## Abstract

Medical devices, such as implants, having a high-modulus alloy. The alloy includes a biocompatible refractory-metal-based alloy having multiple refractory metals. The alloy has an elastic modulus above about 300 GPa. The alloy comprises 30-35% tungsten, 60% molybdenum, and 5-10% niobium. The alloy is absent of rhenium.

## Claims

### Claim 1

A medical device comprising:
a biocompatible refractory-metal-based alloy, comprising multiple refractory metals;
wherein the alloy has an elastic modulus above about 300 GPa;
wherein the alloy comprises 30-35% tungsten and 60% molybdenum;
wherein the alloy further comprises 5-10% niobium; and
wherein the alloy is absent of rhenium.

### Claim 2 (depends on 1)

The medical device of claim 1, wherein the alloy further comprises at least one of chromium, tantalum, hafnium, zirconium, titanium, and yttrium, in the amount each of less than 5 weight pct.

### Claim 3 (depends on 2)

The medical device of claim 2, wherein the alloy further comprises carbon, oxygen, hydrogen and/or nitrogen.

### Claim 4 (depends on 1)

The medical device of claim 1, wherein the alloy is free of ferromagnetic elements.

### Claim 5 (depends on 1)

The medical device of claim 1, wherein the alloy is free of cobalt.

### Claim 6 (depends on 1)

The medical device of claim 1, wherein the alloy is free of nickel.

### Claim 7 (depends on 1)

The medical device of claim 1, wherein the alloy is free of iron.

### Claim 8 (depends on 1)

The medical device of claim 1, wherein the alloy is free of cobalt, nickel, and iron.

### Claim 9 (depends on 1)

The medical device of claim 1, wherein the device is an implant.

### Claim 10 (depends on 9)

The medical device of claim 9, wherein the device is a spinal implant.

### Claim 11 (depends on 10)

The medical device of claim 10, wherein the implant comprises a rod.

### Claim 12 (depends on 10)

The medical device of claim 10, wherein the implant comprises a rod-to-rod connector.

### Claim 13 (depends on 10)

The medical device of claim 10, wherein the implant comprises a plate.

### Claim 14 (depends on 10)

The medical device of claim 10, wherein the implant comprises a bonescrew, rod-receiver, or screw assembly being a fixed, uni-axial, or multi-axial screw assembly.

### Claim 15 (depends on 9)

The medical device of claim 9, wherein the implant comprises a stent.

### Claim 16 (depends on 15)

The medical device of claim 15, wherein the stent is a cardiovascular stent.

### Claim 17 (depends on 15)

The medical device of claim 15, wherein the stent is a neurovascular stent.

### Claim 18 (depends on 15)

The medical device of claim 15, wherein the stent due to the alloy of the present technology has reduced recoil as compared to convention-material stents.

### Claim 19 (depends on 9)

The medical device of claim 9, wherein the implant is a cardiovascular stent.

### Claim 20 (depends on 1)

The medical device of claim 1, wherein the device is a dental device.

### Claim 21 (depends on 20)

The medical device of claim 20, wherein the device is a dental implant.

### Claim 22 (depends on 1)

The medical device of claim 1, wherein the device is an orthopaedic device.

### Claim 23 (depends on 22)

The medical device of claim 22, wherein the orthopaedic device is an orthopaedic implant.

### Claim 24 (depends on 23)

The medical device of claim 23, wherein the orthopaedic implant is a spinal implant.

### Claim 25 (depends on 1)

The medical device of claim 1, wherein the device is an arthroscopic or cutting device.

### Claim 26 (depends on 1)

The medical device of claim 1, wherein the device is a medical cutting device.

### Claim 27 (depends on 1)

The medical device of claim 1, wherein the device is an orthopaedic joint replacement device.

### Claim 28 (depends on 1)

The medical device of claim 1, wherein the device is an orthopaedic trauma device.

### Claim 29 (depends on 1)

The medical device of claim 1, wherein the device is a cardiovascular device.

### Claim 30 (depends on 1)

The medical device of claim 1, wherein the device is a neurovascular device.

### Claim 31 (depends on 30)

The medical device of claim 30, wherein the device is a neurovascular guidewire.

### Claim 32 (depends on 1)

The medical device of claim 1, wherein the device is a torque-responsive medical delivery device.

### Claim 33 (depends on 1)

The medical device of claim 1, wherein the device is a spinal interbody.

### Claim 34 (depends on 1)

The medical device of claim 1, wherein the device is a spinal disc replacement.

### Claim 35 (depends on 1)

The medical device of claim 1, wherein the alloy is free of ferromagnetic elements.
