# US 12,005,134 B2 · Composition for stimulating facial hair growth and methods of manufacturing a composition for stimulating facial hair growth

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- Number: US 12,005,134 B2
- Document ID: US12005134B2
- Status: Granted
- Kind: B2
- Application number: 17/855,206
- Filed: 2022-06-30
- Published: 2023-01-05
- Granted: 2024-06-11
- Earliest claimed: 2021-06-30
- Applicants: Abe Pharmaceutical
- Inventors: Nicholas D'Angelo; Matthew Weiss
- Web page: https://patentgrep.com/patent/US12005134B2

## CPC

- A61K 8/4953: {containing pyrimidine ring derivatives, e.g. minoxidil}
- A61K 8/34: Alcohols
- A61K 8/342: {Alcohols having more than seven atoms in an unbroken chain}
- A61K 8/63: Steroids; Derivatives thereof
- A61K 8/92: Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K 8/922: {of vegetable origin}
- A61Q 7/00: Preparations for affecting hair growth
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS

## Abstract

A composition for stimulating facial hair growth includes a vasodilator including a medication that stimulates cell proliferation of a plurality of facial follicles of an individual, an additive, and a delivery carrier designed to be applied to the individual, wherein the delivery carrier is further configured to enhance stability of the vasodilator and the additive.

## Claims

### Claim 1

A composition for stimulating facial hair growth, wherein the composition comprises:
a vasodilator comprising a medication, wherein the medication comprises a first agent containing minoxidil, wherein the first agent is present between 0.01-5% of the weight to volume ratio of the composition;
an additive comprising a color element and a stabilizer comprising a radical scavenger and an emulsifier comprising an amphiphilic surfactant, wherein the stabilizer added to the additive comprises N,N′-bis(salicylidene)-1,2-propanediamine; and
a delivery carrier, wherein the delivery carrier is further configured to enhance stability of the first agent and the additive and comprises an applicator configured to deliver the composition.

### Claim 2 (depends on 1)

The composition of claim 1, wherein the vasodilator further comprises a second agent comprising finasteride present between 0.01-3% of the weight to volume ration of the composition.

### Claim 3 (depends on 1)

The composition of claim 1, wherein the vasodilator further comprises a medication comprising an angiotensin-converting enzyme inhibitor.

### Claim 4 (depends on 3)

The composition of claim 3, wherein the medication is configured to promote a telegenic phase to shed the plurality of facial follicles and an anagenic phase to proliferate the plurality of facial follicles.

### Claim 5 (depends on 3)

The composition of claim 3, wherein the medication is configured to hyperpolarize a cell membrane of a cell.

### Claim 6 (depends on 1)

The composition of claim 1, wherein the vasodilator is configured to enhance a permeation rate.

### Claim 7 (depends on 1)

The composition of claim 1, wherein the vasodilator is configured to enhance the permeation rate of a nutrient contained within the composition.

### Claim 8 (depends on 1)

The composition of claim 1, wherein the additive comprises a terpene.

### Claim 9 (depends on 8)

The composition of claim 8, wherein the terpene is configured to enhance absorption of the vasodilator.

### Claim 10 (depends on 1)

The composition of claim 1, wherein the additive comprises an emulsifier comprising diglyceride.

### Claim 11 (depends on 1)

The composition of claim 1, wherein the additive comprises a propellant comprising dimethyl ether.

### Claim 12 (depends on 1)

The composition of claim 1, wherein the additive comprises a moisturizer.

### Claim 13 (depends on 12)

The composition of claim 12, wherein the moisturizer includes a humectant comprising cetyl alcohol.

### Claim 14 (depends on 12)

The composition of claim 12, wherein the moisturizer further comprises jojoba oil.

### Claim 15 (depends on 12)

The composition of claim 12, wherein the moisturizer further comprises coconut oil.

### Claim 16 (depends on 1)

The composition of claim 1, wherein the delivery carrier comprises an ionic liquid configured to reduce a propensity of a polymorphic structure of the vasodilator.

### Claim 17 (depends on 16)

The composition of claim 16, wherein the ionic liquid comprises a room-temperature ionic liquid.