# US 12,005,092 B2 · Herbal composition for breast cancer prevention > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,005,092 B2 - Document ID: US12005092B2 - Status: Granted - Kind: B2 - Application number: 17/962,590 - Filed: 2022-10-10 - Published: 2023-06-22 - Granted: 2024-06-11 - Earliest claimed: 2021-12-22 - Applicants: Laura Mann Kevehazi - Inventors: Laura Mann Kevehazi - Web page: https://patentgrep.com/patent/US12005092B2 ## CPC - A61K 36/074: Ganoderma - A23L 33/105: Plant extracts, their artificial duplicates or their derivatives - A23L 33/40: {Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula} - A61K 31/352: condensed with carbocyclic rings, e.g. methantheline {(cannabinoids A61K31/658)} - A61K 31/404: Indoles, e.g. pindolol - A61K 33/04: Sulfur, selenium or tellurium; Compounds thereof - A61K 33/18: Iodine; Compounds thereof - A61K 36/185: Magnoliopsida (dicotyledons) - A61K 36/47: Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean) - A61K 36/82: Theaceae (Tea family), e.g. camellia - A61K 36/8962: Allium, e.g. garden onion, leek, garlic or chives - A61K 47/02: Inorganic compounds - A61P 35/00: Antineoplastic agents - G06F 21/32: using biometric data, e.g. fingerprints, iris scans or voiceprints - G06V 10/758: {Involving statistics of pixels or of feature values, e.g. histogram matching} - G06V 40/1318: {using electro-optical elements or layers, e.g. electroluminescent sensing} - G06V 40/1353: {Extracting features related to minutiae or pores} - G06V 40/1359: {Extracting features related to ridge properties; Determining the fingerprint type, e.g. whorl or loop} - G06V 40/1376: {Matching features related to ridge properties or fingerprint texture} - A23V 2002/00: Food compositions, function of food ingredients or processes for food or foodstuffs - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A23L: FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF (preservation thereof A23B) - A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS - G06F: ELECTRIC DIGITAL DATA PROCESSING (computer systems based on specific computational models G06N) - G06V: IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING - A23V: INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION ## Abstract A composition for use in protecting the breast tissue and significantly lowering the high risk for breast cancer development in women includes Ganoderma lucidum, Quercetine, Embilica officinalis, Indole 3 carbinol, Camellia sinensis, Allium sativum, Iodine, and Selenium. ## Claims ### Claim 1 A composition comprising multiple ingredients, each in effective amounts, which treats breast cancer in a subject in need thereof by inhibiting breast cancer cells, the composition comprising: a medicinal mushroom, the medicinal mushroom being one of Ganoderma lucidum, Phellinus linteus, Trametes vesicolor, Inonotus oblicus and Grifola frondosa, said medicinal mushroom in an amount of between 50-450 mg; Quercetin, said Quercetin in an amount of between 125 to 450 mg; Embilica officinalis, said Embilica officinalis in an amount of between 100-450 mg; Indole 3 Carbinol, said Indole 3 Carbinol in an amount of between 50-300 mg; Camellia sinensis, said Camellia sinensis in an amount equivalent to between 300 mg to 1800 mg; Allium sativum, said Allium sativum in an amount equivalent to between 1000-3000 mg; Iodine, said Iodine in an amount of between 100-400 mcg; and Selenium, said Selenium in an amount of between 20-120 mcg, wherein, said composition being encapsulated and suitable for oral administration. ### Claim 2 (depends on 1) The composition according to claim 1, wherein the Camellia sinensis is a Green tea extract containing polyphenolic catechins; and the Selenium is one or more of Selenomethionine, Selenocysteine or Sodium selenate. ### Claim 3 (depends on 1) The composition according to claim 1, wherein said composition is in the form of a liquid, powder, solid, or gel. ### Claim 4 (depends on 1) The composition according to claim 1, wherein the composition comprises at least one of a pharmaceutically acceptable carrier, excipient, diluent, coloring and flavoring agent. ### Claim 5 (depends on 1) The composition according to claim 1, wherein, the amount of the medicinal mushroom is 375 mg; the amount of Quercetin Dihydrate 95% is 375 mg; the amount of Embilica officinalis is 300 mg; the amount of Indole 3 Carbinol is 150 mg; the amount of Camellia sinensis is 90 mg extract 12:1, equivalent to 1080 mg; the amount of Allium sativum is 0.30 mg extract 100:1, equivalent to 3000 mg; the amount of Iodine is 300 mcg; and the amount of Selenium is 60 mcg. ### Claim 6 A composition for use in a subject at risk of developing breast cancer by protecting breast cells from malignant changes and lowering the risk for breast cancer development, the composition comprising: Ganoderma lucidum in an amount from 125-375 mg; Quercetin Dihydrate 95% in an amount from 125-375 mg; Embilica officinalis in an amount from 100-300 mg; Indole 3 Carbinol in an amount from 50-150 mg; Camellia sinensis in an amount equivalent to 360-1080 mg; Allium sativum in an amount equivalent to 1000-3000 mg; Iodine in an amount from 100-300 mcg; and Selenium in an amount from 20-60 mcg, wherein, said composition being encapsulated in capsule format suitable for oral administration. ### Claim 7 (depends on 6) A composition according to claim 6 for women currently undergoing, or having undergone in the past, Hormone Replacement Therapy. ### Claim 8 (depends on 6) The composition according to claim 6 wherein the composition is in the form of a powder, a gel, or a liquid. ### Claim 9 (depends on 6) The composition according to claim 6, wherein, the amount of Ganoderma Lucidum is 125 mg; the amount of Quercetin Dihydrate 95% is 125 mg; the amount of Embilica officinalis is 100 mg; the amount of Indole 3 Carbinol is 50 mg; the amount of Camellia sinensis is equivalent to 360 mg; the amount of Allium sativum is equivalent to 1000 mg; the amount of Iodine is 100 mcg; and the amount of Selenium is 20 mcg. ### Claim 10 (depends on 6) The composition according to claim 6, wherein, the amount of Ganoderma Lucidum is 375 mg; the amount of Quercetin Dihydrate 95% is 375 mg; the amount of Embilica officinalis is 300 mg; the amount of Indole 3 Carbinol is 150 mg; the amount of Camellia sinensis extract is 90 mg; the amount of Allium sativum extract is 30 mg; the amount of Iodine is 300 mcg; and the amount of Selenium is 60 mcg. ### Claim 11 A composition for daily administration for women at risk of developing breast cancer arising from at least one of BRAC1 and BRAC2 mutations, high breast density, family history, and having had cancer in the past, to reduce the risk of breast cancer development, said composition comprising multiple ingredients, delivered as a capsule suitable for oral administration, comprising: Ganoderma lucidum in an amount from 125-375 mg; Quercetin Dihydrate 95% in an amount from 125-375 mg; Embilica officinalis in an amount from 100-300 mg; Indole 3 Carbinol in an amount from 50-150 mg; Camellia sinensis extract 12:1 in an amount from 30-90 mg; Allium sativum extract 100:1 in an amount from 10-30 mg; Iodine in an amount from 100-300 mcg; and Selenium in an amount from 20-60 mcg. ### Claim 12 (depends on 11) The composition according to claim 11, wherein the composition is a powder, a liquid, or a gel. ### Claim 13 (depends on 11) The composition according to claim 11, wherein the composition comprises pharmaceutically acceptable carrier, excipients, diluent, coloring or flavoring agents. ### Claim 14 (depends on 11) The composition according to claim 11, wherein the Camellia sinensis is derived from Green tea extract 12:1 having 50-95% polyphenolic catechins, and Allium sativum is derived from garlic extract 100:1. ### Claim 15 (depends on 11) The composition according to claim 11, wherein, the amount of Ganoderma Lucidum is 125 mg; the amount of Quercetin Dihydrate 95% is 125 mg; the amount of Embilica officinalis is 100 mg; the amount of Indole 3 Carbinol is 50 mg; the amount of Camellia sinensis extract is 30 mg; the amount of Allium sativum extract is 10 mg; the amount of Iodine is 100 mcg; and the amount of Selenium is 20 mcg. ### Claim 16 (depends on 11) The composition according to claim 11, wherein, the amount of Ganoderma Lucidum is 375 mg; the amount of Quercetin Dihydrate 95% is 375 mg; the amount of Embilica officinalis is 300 mg; the amount of Indole 3 Carbinol is 150 mg; the amount of Camellia sinensis is equivalent to 1080 mg; the amount of Allium sativum is equivalent to 30 mg; the amount of Iodine is 300 mcg; and the amount of Selenium is 60 mcg. ### Claim 17 A composition for inhibiting breast cancer proliferation by administering a daily dose of the composition, said composition in a dosage form for oral delivery, comprising: Ganoderma lucidum from 125-450 mg; Quercetin Dihydrate 95% from 125-450 mg; Embilica officinalis from 100-300 mg; Indole 3 Carbinol from 50-300 mg; Camellia sinensis in an amount equivalent to 300-1080 mg; Allium sativum in an amount equivalent to 1000-3000 mg; Iodine from 100-400 mcg; and Selenium from 20-120 mcg. ### Claim 18 (depends on 17) The composition according to claim 17, further comprising at least one of a pharmaceutically acceptable carrier, excipients, diluent, coloring and flavoring agents. ### Claim 19 (depends on 17) The composition according to claim 17, wherein, the amount of Ganoderma Lucidum is 125 mg; the amount of Quercetin Dihydrate 95% is 125 mg; the amount of Embilica officinalis is 100 mg; the amount of Indole 3 Carbinol is 50 mg; the amount of Camellia sinensis extract is 30 mg; the amount of Allium sativum extract is 10 mg; the amount of Iodine is 300 mcg; and the amount of Selenium is 60 mcg. ### Claim 20 (depends on 4) The composition according to claim 4, wherein, the amount of Ganoderma Lucidum is 375 mg; the amount of Quercetin Dihydrate 95% is 375 mg; the amount of Embilica officinalis is 300 mg; the amount of Indole 3 Carbinol is 150 mg; the amount of Camellia sinensis extract 90 mg, equivalent to 1080 mg; the amount of Allium sativum equivalent to 3000 mg; the amount of Iodine is 100 mcg; and the amount of Selenium is 60 mcg. ### Claim 21 (depends on 1) The composition according to claim 1, wherein, the amount of the medicinal mushroom is 125 mg; the amount of Quercetin Dihydrate 95% is 125 mg; the amount of Embilica officinalis is 100 mg; the amount of Indole 3 Carbinol is 50 mg; the amount of Camellia sinensis is 30 mg extract 12:1, equivalent to 360 mg; the amount of Allium sativum is 10 mg extract 100:1, equivalent to 1000 mg; the amount of Iodine is 100 mcg; and the amount of Selenium is 20 mcg.