# US 12,005,026 B2 · Infusion bag > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,005,026 B2 - Document ID: US12005026B2 - Status: Granted - Kind: B2 - Application number: 17/253,424 - Filed: 2019-08-20 - Published: 2021-06-10 - Granted: 2024-06-11 - Earliest claimed: 2018-08-21 - Assignees: Fresenius Kabi Deutschland GmbH - Applicants: Fresenius Kabi Deutschland GmbH - Inventors: Torsten Brandenburger; Beatrix Heuel-Hoemmen - Web page: https://patentgrep.com/patent/US12005026B2 ## CPC - A61J 1/10: Bag-type containers - A61J 1/1406: {Septums, pierceable membranes} - A61J 1/1431: {Permanent type, e.g. welded or glued} - A61J 1/1481: {with connection retaining means, e.g. thread or snap-fit} - B32B 3/08: characterised by added members at particular parts {(layer formed of separate pieces of material which are juxtaposed side-by-side B32B3/14, B32B3/18)} - B32B 27/08: of synthetic resin - B32B 27/302: {comprising aromatic vinyl (co)polymers, e.g. styrenic (co)polymers} - B32B 27/32: comprising polyolefins {(comprising vinyl (co)polymers or acrylic (co)polymers B32B27/30)} - B32B 2250/03: 3 layers - B32B 2250/24: All layers being polymeric - B32B 2250/246: All polymers belonging to those covered by groups B32B27/32 and B32B27/30 - B32B 2270/00: Resin or rubber layer containing a blend of at least two different polymers - B32B 2274/00: Thermoplastic elastomer material - B32B 2307/412: Transparent - B32B 2307/51: Elastic - B32B 2307/536: Hardness - B32B 2307/54: Yield strength; Tensile strength - B32B 2307/558: Impact strength, toughness - B32B 2307/5825: Tear resistant - B32B 2307/732: Dimensional properties - B32B 2439/46: Bags - B32B 2439/80: Medical packaging - A61J: CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE - B32B: LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM ## Abstract The invention relates to a medical package designed as an infusion bag, which medical package is made from multi-layer films that are welded to one another and is filled with a medical liquid for infusion and/or for parenteral nutrition. The invention is described by a medical package designed as an infusion bag, which is made up of a film comprising multiple layers welded to one another and has at least one weld seam, preferably longitudinal and transverse weld seams, and is filled with a medical liquid. The multi-layer film has at least one inner layer of a matrix-phase polymer system, an intermediate layer of a matrix-phase polymer system, and an outer layer of a matrix-phase polymer system. The matrix polymer of the matrix-phase polymer system of the inner layer, the intermediate layer and the outer layer in each case comprises a polypropylene polymer (PP) having defined parts by weight in the individual layers, and the phase polymer of the matrix-phase polymer system of the inner layer, the intermediate layer and the outer layer in each case comprises a styrene-ethylene/butyl-styrene block copolymer (SEBS) having defined parts by weight in the individual layers. The film is characterised in that the styrene-ethylene/butyl-styrene block copolymer (SEBS) of the intermediate layer has a styrene-ethylene/butylene ratio (S/EBM) and the styrene-ethylene/butylene-styrene block copolymer (SEBS) of the outer layer has a styrene-ethylene/butylene ratio (S/EBA), in which S/EBA>S/EBM. It has been shown that in this way the mechanical properties of the multi-layer film can be improved, in particular in the event of expansion of the multi-layer film in the region of the weld seams. The improved mechanical properties appear both at room temperature and also at lower temperatures of down to 4° C. ## Claims ### Claim 1 A film comprising: an inner layer; an outer layer comprising a styrene-ethylene/butylene-styrene block copolymer in a matrix of a polymer; and an intermediate layer disposed between the inner layer and the outer layer, the intermediate layer comprising a styrene-ethylene/butylene-styrene block copolymer in a matrix of a polymer, wherein a ratio, by weight, of styrene to ethylene and butylene of the outer layer is between 0.18 and 0.28, and wherein a ratio, by weight, of styrene to ethylene and butylene of the intermediate layer is between 0.10 and 0.16. ### Claim 2 (depends on 1) The film of claim 1, wherein the ratio, by weight, of styrene to ethylene and butylene of the outer layer is greater than 1.2 times the ratio, by weight, of styrene to ethylene and butylene of the intermediate layer. ### Claim 3 (depends on 2) The film of claim 2, wherein the ratio, by weight, of styrene to ethylene and butylene of the outer layer is greater than 1.5 times the ratio, by weight, of styrene to ethylene and butylene of the intermediate layer. ### Claim 4 (depends on 1) The film of claim 1, wherein the polymer of the outer layer is polypropylene, and wherein the polymer of the intermediate layer is polypropylene. ### Claim 5 (depends on 4) The film of claim 4, wherein the inner layer comprises a styrene-ethylene/butylene-styrene block copolymer in a matrix of polypropylene. ### Claim 6 (depends on 5) The film of claim 5, wherein a ratio, by weight, of styrene to ethylene and butylene of the inner layer is greater than the ratio, by weight, of styrene to ethylene and butylene of the intermediate layer. ### Claim 7 (depends on 6) The film of claim 6, wherein the ratio, by weight, of styrene to ethylene and butylene of the inner layer is greater than 1.2 times the ratio, by weight, of styrene to ethylene and butylene of the intermediate layer. ### Claim 8 (depends on 7) The film of claim 7, wherein the ratio, by weight, of styrene to ethylene and butylene of the inner layer is greater than 1.5 times the ratio, by weight, of styrene to ethylene and butylene of the intermediate layer. ### Claim 9 (depends on 5) The film of claim 5, wherein a ratio, by weight, of styrene to ethylene and butylene of the inner layer is equal to the ratio, by weight, of styrene to ethylene and butylene of the outer layer. ### Claim 10 (depends on 1) The film of claim 1, wherein the intermediate layer further comprises a styrene-isoprene-styrene block copolymer in the matrix of the polymer. ### Claim 11 (depends on 1) The film of claim 1, wherein the ratio, by weight, of styrene to ethylene and butylene of the outer layer is between 0.20 and 0.24, and wherein the ratio, by weight, of styrene to ethylene and butylene of the intermediate layer is between 0.13 and 0.14. ### Claim 12 (depends on 1) The film of claim 1, wherein the inner layer comprises styrene-ethylene/butylene-styrene block copolymer in a matrix of a polymer, wherein a ratio, by weight, of styrene to ethylene and butylene of the inner layer is between 0.18 and 0.28. ### Claim 13 (depends on 12) The film of claim 12, wherein the ratio, by weight, of styrene to ethylene and butylene of the inner layer is between 0.20 and 0.24, and wherein the ratio, by weight, of styrene to ethylene and butylene of the intermediate layer is between 0.13 and 0.14. ### Claim 14 A medical package comprising a film, the medical package having at least one seam, and the medical package configured to be filled with a liquid, wherein the film comprises: an inner layer; an outer layer comprising a styrene-ethylene/butylene-styrene block copolymer in a matrix of a polymer; and an intermediate layer disposed between the inner layer and the outer layer, the intermediate layer comprising a styrene-ethylene/butylene-styrene block copolymer in a matrix of a polymer, wherein a ratio, by weight, of styrene to ethylene and butylene of the outer layer is between 0.18 and 0.28, and wherein a ratio, by weight, of styrene to ethylene and butylene of the intermediate layer is between 0.10 and 0.16. ### Claim 15 (depends on 14) The medical package of claim 14, wherein the ratio, by weight, of styrene to ethylene and butylene of the outer layer is greater than 1.2 times the ratio, by weight, of styrene to ethylene and butylene of the intermediate layer. ### Claim 16 (depends on 14) The medical package of claim 14, wherein the polymer of the outer layer is polypropylene, wherein the polymer of the matrix of the intermediate layer is polypropylene, and wherein the inner layer comprises a styrene-ethylene/butylene-styrene block copolymer in a matrix of polypropylene. ### Claim 17 (depends on 14) The medical package of claim 14, wherein the intermediate layer further comprises a styrene-isoprene-styrene block copolymer in the matrix of the polymer. ### Claim 18 (depends on 14) The medical package of claim 14, wherein the inner layer comprises a styrene-ethylene/butylene-styrene block copolymer in a matrix of a polymer, and wherein a ratio, by weight, of styrene to ethylene and butylene of the inner layer is between 0.18 and 0.28.