# US 12,004,908 B2 · Ultrasound imaging system for high resolution wideband harmonic imaging

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- Number: US 12,004,908 B2
- Document ID: US12004908B2
- Status: Granted
- Kind: B2
- Application number: 17/050,235
- Filed: 2019-04-15
- Published: 2021-03-18
- Granted: 2024-06-11
- Earliest claimed: 2018-04-24
- Assignees: Koninklijke Philips N.V.
- Applicants: Koninklijke Philips N.V.
- Inventors: Xiaowen Hu; Gary Cheng-How Ng; David Hope Simpson
- Web page: https://patentgrep.com/patent/US12004908B2

## CPC

- A61B 8/5269: {involving detection or reduction of artifacts}
- A61B 8/145: {characterised by scanning multiple planes}
- A61B 8/4444: {related to the probe}
- A61B 8/4488: {the transducer being a phased array}
- A61B 8/5207: {involving processing of raw data to produce diagnostic data, e.g. for generating an image}
- A61B 8/5246: {combining images from the same or different imaging techniques, e.g. color Doppler and B-mode}
- A61B 8/54: {Control of the diagnostic device}
- G01S 7/5202: {for pulse systems}
- G01S 7/52026: {Extracting wanted echo signals (Doppler systems G01S15/50; Doppler short range imaging systems G01S15/8979)}
- G01S 7/52038: {involving non-linear properties of the propagation medium or of the reflective target}
- G01S 7/52047: {for elimination of side lobes or of grating lobes; for increasing resolving power}
- G01S 7/52077: {with means for elimination of unwanted signals, e.g. noise or interference}
- G01S 15/8952: {using discrete, multiple frequencies}
- G01S 15/8963: {using pulse inversion}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G01S: RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES

## Abstract

An ultrasound imaging system transmits two beams in succession in the same beam direction, the waveform of the second beam being a phase inverted form of the first waveform, and each waveform containing first and second major frequency components. Echoes are received from along the beam direction in response to each beam transmission, and are processed by additively and subtractively combining the two echo sequences on a common depth basis. The echo components resulting from this processing extend from high frequencies for good near field resolution to low frequencies for good depth penetration, and include fundamental, harmonic, and sum or difference frequency components. The linear and nonlinear echo signal components may be frequency compounded for speckle reduction.

## Claims

### Claim 1

An ultrasound system for producing high resolution wideband harmonic images comprising:
an ultrasound probe comprising an array transducer adapted to transmit ultrasound beams and receive echo signals from along directions of transmitted ultrasound beams;
a transmitter, coupled to the ultrasound probe, and adapted to control the probe to transmit first and second differently modulated transmit waveforms in a common beam direction, each waveform comprising two major frequency components;
a buffer adapted to store echo signals received in response to transmission of at least the first transmit waveform;
a summer coupled to the buffer and adapted to additively combine echo signals on a spatial basis which are received in response to transmission of the first and second transmit waveforms;
a subtractor coupled to the buffer and adapted to subtractively combine echo signals on a spatial basis which are received in response to transmission of the first and second transmit waveforms;
wherein the summer is further adapted to produce nonlinear echo signal components at an output and the subtractor is further adapted to produce linear echo signal components at an output; and further comprising:
a first time-varying filter coupled to an output of the summer and adapted to vary from a high pass filter characteristic to a lower band filter characteristic as nonlinear echo signals are received from increasing depths;
and a second time-varying filter coupled to an output of the subtractor and adapted to vary from a high pass filter characteristic to a lower band filter characteristic as linear echo signals are received from increasing depths;
and an image processor adapted to produce an ultrasound image, and characterized in that: the summer and the subtractor are further adapted to produce four different major frequency components, each of which is either a fundamental frequency component, a harmonic frequency component, a sum frequency component, or a difference frequency components, and all of which are below the major frequency of the second harmonic component of the transmit waveform of the highest frequency.

### Claim 2 (depends on 1)

The ultrasound system of claim 1, wherein the buffer is further adapted to store echo signals received in response to transmission of the second transmit waveform.

### Claim 3 (depends on 1)

The ultrasound system of claim 1, wherein the transmitter is further adapted to control the probe to transmit a first waveform, and a second waveform which is an inverted form of the first waveform.

### Claim 4 (depends on 2)

The ultrasound system of claim 2, wherein the transmitter is further adapted to control the probe to transmit a first waveform, and a second waveform which is in a 180° phase relationship with the first waveform.

### Claim 5 (depends on 1)

The ultrasound system of claim 1, wherein the array transducer is further adapted to receive echo signals which are at fundamental, harmonic, and sum or difference frequencies of the two component frequencies.

### Claim 6 (depends on 5)

The ultrasound system of claim 5, wherein the summer is further adapted to produce echo signals of harmonic, sum, and difference frequency components.

### Claim 7 (depends on 1)

The ultrasound system of claim 1, wherein the subtractor is further adapted to produce echo signals of fundamental transmit frequency components.

### Claim 8 (depends on 7)

The ultrasound system of claim 7, further comprising a combiner, coupled to the summer and the subtractor, and adapted to produce echo signals of fundamental, harmonic, and sum or difference frequency components.

### Claim 9 (depends on 8)

The ultrasound system of claim 8, further comprising a tracking filter coupled to the combiner and the image processor.

### Claim 10 (depends on 1)

The ultrasound system of claim 1, wherein the second time-varying filter is further adapted to accentuate the contributions of high frequency linear echo signals to an image at a shallow depth and to accentuate the contributions of low frequency linear echo signals to the image at a deeper depth.

### Claim 11 (depends on 10)

The ultrasound system of claim 10, wherein the first time-varying filter is further adapted to accentuate the contributions of nonlinear echo signals to the image in the mid-range.

### Claim 12 (depends on 1)

The ultrasound system of claim 1, further comprising:
a first detector coupled to an output of the first time-varying filter;
a second detector coupled to an output of the second time-varying filter;
and a summing circuit coupled to outputs of the first and second detectors,
wherein the summing circuit is adapted to produce speckle-reduced echo signals.

### Claim 13 (depends on 12)

The ultrasound system of claim 12, further comprising:
a first weighting circuit coupled between the first detector and the summing circuit and adapted to apply weights which vary as a function of depth to nonlinear echo signals; and
a second weighting circuit coupled between the second detector and the summing circuit and adapted to apply weights which vary as a function of depth to linear echo signals.

### Claim 14 (depends on 13)

The ultrasound system of claim 13, wherein the first weighting circuit is further adapted to apply the greatest weights to echo signals at mid-range depths of field; and
wherein the second weighting circuit is further adapted to apply the greatest weights to echo signals at shallow and deeper depths of field.