# US 12,004,847 B2 · Radial artery signal measuring device

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- Number: US 12,004,847 B2
- Document ID: US12004847B2
- Status: Granted
- Kind: B2
- Application number: 17/342,675
- Filed: 2021-06-09
- Published: 2021-12-16
- Granted: 2024-06-11
- Earliest claimed: 2020-06-10
- Assignees: National Yang Ming Chiao Tung University
- Applicants: National Yang Ming Chiao Tung University
- Inventors: Paul C.P. Chao; Chia-Hsiu Yeh
- Web page: https://patentgrep.com/patent/US12004847B2

## CPC

- A61B 5/0261: {using optical means, e.g. infrared light}
- A61B 5/0295: using plethysmography, i.e. measuring the variations in the volume of a body part as modified by the circulation of blood therethrough, e.g. impedance plethysmography
- A61B 2562/0238: Optical sensor arrangements for performing transmission measurements on body tissue
- A61B 2562/164: the sensor is mounted in or on a conformable substrate or carrier
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

A radial artery signal measuring device includes a flexible signal sensor, a signal processor, and a flexible cable. The flexible signal sensor is fixed on a skin surface over a radial artery by a patch during use. The flexible signal sensor includes a flexible substrate, at least one infrared light source, and a light detector. The at least one infrared light source is used to emit an infrared light to the radial artery, wherein the wavelength of the light source is infrared light greater than 1000 nm. The light detector is used to receive the infrared light reflected by the radial artery and generate a radial artery signal. The signal processor includes a housing for fitting the wrist of a user, a circuit board, a microprocessor, and a battery. The flexible cable is used to transmit the radial artery signal to the microprocessor.

## Claims

### Claim 1

A radial artery signal measuring device, comprising:
a flexible signal sensor configured to be fixed on a first position of a skin surface over a radial artery of a wrist of a user by a patch during use, wherein the flexible signal sensor comprises:
a flexible substrate;
at least one infrared light source disposed on the flexible substrate and configured to emit an infrared light to the radial artery, wherein a wavelength of the infrared light is greater than 1000 nm; and
a light detector disposed on the flexible substrate and configured to receive the infrared light reflected by the radial artery to generate a radial artery signal;
a signal processor spatially separated from the flexible signal sensor to be movably disposed on a second position of the skin surface of the wrist of the user during use, wherein the signal processor comprises:
a circuit board;
a microprocessor disposed on the circuit board and configured to analyze the radial artery signal;
a battery disposed on the circuit board for providing power to the microprocessor; and
a housing for surrounding the circuit board, the microprocessor, and the battery, and for fitting the wrist of the user; and
a flexible cable used to electrically connect the flexible signal sensor and the signal processor to transmit the radial artery signal to the microprocessor from the flexible signal sensor and transmit electrical energy to the flexible signal sensor from the battery, such that the flexible signal sensor has no displacement on the skin surface of the user when the signal processor moves on the wrist of the user.

### Claim 2 (depends on 1)

The radial artery signal measuring device of claim 1, wherein the at least one infrared light source is arranged to surround the light detector.

### Claim 3 (depends on 1)

The radial artery signal measuring device of claim 1, wherein the at least one infrared light source is an infrared light emitting diode, an infrared organic light emitting diode, or any combinations thereof.

### Claim 4 (depends on 1)

The radial artery signal measuring device of claim 1, wherein the light detector is an organic photodetector.

### Claim 5 (depends on 1)

The radial artery signal measuring device of claim 1, wherein the light detector is a quantum dot detector.