# US 12,004,819 B2 · System and method of performing treatment along a lumen network

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- Number: US 12,004,819 B2
- Document ID: US12004819B2
- Status: Granted
- Kind: B2
- Application number: 17/482,714
- Filed: 2021-09-23
- Published: 2022-01-13
- Granted: 2024-06-11
- Earliest claimed: 2016-05-10
- Assignees: Covidien LP
- Applicants: Covidien LP
- Inventors: William S. Krimsky
- Web page: https://patentgrep.com/patent/US12004819B2

## CPC

- A61B 34/20: Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
- A61B 1/00: Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes (examination of body cavities or body tracts using ultrasonic, sonic or infrasonic waves A61B8/12; endoscopic instruments for taking cell samples or for biopsy A61B10/04); Illuminating arrangements therefor (for the eyes A61B3/00)
- A61B 5/061: {Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body (A61B1/00158 takes precedence)}
- A61B 18/02: by cooling, e.g. cryogenic techniques
- A61B 18/1492: {having a flexible, catheter-like structure, e.g. for heart ablation (A61B18/1477 takes precedence)}
- A61B 18/1815: {using microwaves}
- A61B 34/10: Computer-aided planning, simulation or modelling of surgical operations
- A61B 34/25: {User interfaces for surgical systems}
- A61K 48/0075: {characterised by an aspect of the delivery route, e.g. oral, subcutaneous}
- A61M 25/0105: {Steering means as part of the catheter or advancing means; Markers for positioning (systems for detection of markers A61B)}
- A61N 5/1002: {Intraluminal radiation therapy}
- A61N 5/1049: {for verifying the position of the patient with respect to the radiation beam}
- A61B 1/0005: {combining images e.g. side-by-side, superimposed or tiled}
- A61B 1/2676: {Bronchoscopes}
- A61B 2018/00541: {Lung or bronchi}
- A61B 2018/00577: {Ablation}
- A61B 2018/00898: {Alarms or notifications created in response to an abnormal condition}
- A61B 2018/00982: {combined with or comprising means for visual or photographic inspections inside the body, e.g. endoscopes}
- A61B 2018/00994: {combining two or more different kinds of non-mechanical energy or combining one or more non-mechanical energies with ultrasound}
- A61B 2034/105: {Modelling of the patient, e.g. for ligaments or bones}
- A61B 2034/107: {Visualisation of planned trajectories or target regions}
- A61B 2034/2051: {Electromagnetic tracking systems}
- A61B 2090/364: {Correlation of different images or relation of image positions in respect to the body}
- A61B 2090/368: {changing the image on a display according to the operator's position}
- A61M 2025/0166: {Sensors, electrodes or the like for guiding the catheter to a target zone, e.g. image guided or magnetically guided}
- A61N 2005/1024: {Seeds}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)

## Abstract

Disclosed are systems, devices, and methods for performing treatment along a lumen network, an exemplary method comprising receiving image data of a patient's lungs, mapping one or more luminal networks inside the patient's lungs based on the received image data, identifying a treatment target in the image data, determining a luminal pathway to the treatment target via at least one of the luminal networks, configuring treatment parameters for treatment of the treatment target and at least one of the luminal networks, navigating a tool inside at least one of the luminal networks to the treatment target, treating the treatment target with a primary treatment modality, and treating the luminal pathway of at least one of the luminal networks leading to or from the treatment target with a secondary treatment modality.

## Claims

### Claim 1

A system for enabling treatment along a lumen of a luminal network, the system comprising:
a tool configured to be navigated through the luminal network and to treat via high dose radiation brachytherapy;
a display configured to display a user interface; and
a computing device operably coupled to the display, the computing device including a memory storing instructions which when executed cause the computing device to:
receive image data of the luminal network;
generate a pathway to a treatment target within the lumen of the luminal network;
cause the display to display the pathway generated to facilitate navigation of the tool along the pathway to the treatment target within the lumen of the luminal network for treatment of the treatment target with high dose radiation brachytherapy; and
cause the display to display the lumen of the luminal network leading to or from the treatment target to facilitate navigation for treatment of the lumen with a different treatment modality.

### Claim 2 (depends on 1)

The system according to claim 1, wherein the computing device is configured to generate treatment parameters for at least one of treatment of the treatment target or treatment of the lumen.

### Claim 3 (depends on 1)

The system according to claim 1, wherein the computing device is configured to display guidance for at least one of treatment of the treatment target or treatment of the lumen, the guidance including at least one of a planned treatment zone, a current treatment zone, or a progress of treatment.

### Claim 4 (depends on 1)

The system according to claim 1, wherein the luminal network is selected from the group consisting of a pulmonary network, a vascular network, and a lymphatic network.

### Claim 5 (depends on 1)

The system according to claim 1, wherein the computing device is configured to track locations of the tool as the tool is navigated along the pathway.

### Claim 6 (depends on 5)

The system according to claim 5, wherein the computing device is configured to cause the display to display the locations of the tool as the tool is navigated along the pathway.

### Claim 7 (depends on 1)

The system according to claim 1, wherein the different treatment modality is selected from the group consisting of microwave ablation therapy, radio frequency ablation therapy, chemotherapy, radiation therapy, cryotherapy, and gene therapy.

### Claim 8 (depends on 1)

The system according to claim 1, wherein the computing device is configured to:
generate a second pathway to the treatment target within a second lumen of the luminal network; and
cause the display to display the second pathway generated to facilitate navigation of the tool along the second pathway to the treatment target within the second lumen of the luminal network for treatment of the second lumen with at least one of the high dose radiation brachytherapy or the different treatment modality.

### Claim 9 (depends on 1)

The system according to claim 1, wherein the computing device is configured to cause the display to render the luminal network based on the image data received.