# US 12,004,548 B2 · Method for producing black ginseng concentrate with increased prosapogenin ginsenoside content using continuous steaming-drying technique and combined concentration technology

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- Number: US 12,004,548 B2
- Document ID: US12004548B2
- Status: Granted
- Kind: B2
- Application number: 17/868,959
- Filed: 2022-07-20
- Published: 2023-08-17
- Granted: 2024-06-11
- Earliest claimed: 2022-02-11
- Assignees: Daedong Korea Ginseng Co., Ltd
- Applicants: Daedong Korea Ginseng Co., Ltd
- Inventors: Sung-Keun Choi; Sung Soo Jang; Chang-Soon Lee; Byeong-Seon Jeon; Kun Hee Lee; Kyung Su Lee; Han Sol Lee; Hye Jeong Jeon; Byoung Man Kong
- Web page: https://patentgrep.com/patent/US12004548B2

## CPC

- A23L 5/51: {Concentration}
- A23L 5/13: {using water or steam}
- A23L 19/00: Products from fruits or vegetables; Preparation or treatment thereof (marmalades, jams, jellies or the like A23L21/10; treating harvested fruit or vegetables in bulk A23N)
- A23L 19/10: of tuberous or like starch containing root crops
- A23L 33/105: Plant extracts, their artificial duplicates or their derivatives
- A61K 36/11: Pteridophyta or Filicophyta (ferns)
- A61K 36/258: Panax (ginseng)
- A61K 36/282: Artemisia, e.g. wormwood or sagebrush
- A61K 36/35: Caprifoliaceae (Honeysuckle family)
- A61P 43/00: Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- B01D 1/0082: {Regulation; Control}
- A23V 2200/30: Foods, ingredients or supplements having a functional effect on health
- A61K 2236/00: Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A23L: FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF (preservation thereof A23B)
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- B01D: SEPARATION (separating solids from solids by wet methods B03B, B03D; by pneumatic jigs or tables B03B; by other dry methods B07; magnetic or electrostatic separation of solid materials from solid materials or fluids, separation by high-voltage electric fields B03C; centrifuges, vortex apparatus B04; presses per se for squeezing-out liquid from liquid-containing material B30B9/02; treatment of water C02F, e.g. softening by ion-exchange C02F1/42; {arrangements of air intake cleaners in gas turbine plants F02C7/05} ; arrangements or mounting of filters in air-conditioning, air-humidification or ventilation F24F13/28)
- A23V: INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION

## Abstract

A method for producing black ginseng concentrate is characterized by including steps of adding red ginseng to a continuous steaming-dryer followed by steaming, cooling, and drying to prepare black ginseng, carrying out extraction by adding alcohol to crushed black ginseng obtained by crushing the black ginseng prepared above followed by filtration to prepare black ginseng extract, and concentrating the black ginseng extract prepared above by using a plate type evaporative concentrator followed by heat treatment, and the present invention also relates to black ginseng concentrate prepared by the aforementioned method.

## Claims

### Claim 1

A method for producing black ginseng concentrate, the method comprising:
(1) steaming ginseng followed by drying to prepare red ginseng;
(2) carrying out extraction by adding water to a black ginseng mixture containing black ginseng, Patrinia scabiosaefolia roots, Persicaria hydropiper leaves, and Persicaria thunbergii leaves followed by filtration to prepare a mixed plant extract;
(3) having the red ginseng, which is prepared in the step (1), immersed for 2 to 4 hours in the mixed plant extract prepared in the step (2) followed by recovery-recovering the red ginseng from the extract;
(4) placing the red ginseng recovered in the step (3) in a steaming dryer followed by steaming, cooling, and drying to prepare black ginseng;
(5) carrying out extraction of crushed black ginseng, which is obtained by crushing the black ginseng prepared in the step (4), by adding alcohol followed by filtration to prepare a black ginseng extract; and
(6) concentrating the black ginseng extract prepared in the step (5) by using an evaporative concentrator followed by heat treatment.

### Claim 2 (depends on 1)

The method of claim 1, wherein the black ginseng mixture of the step (2) is a black ginseng mixture in which, based on the total weight of black ginseng mixture, 48 to 52% by weight of black ginseng, 18 to 22% by weight of Patrinia scabiosaefolia roots, 18 to 22% by weight of Persicaria hydropiper leaves, and 8 to 12% by weight of Persicaria thunbergii leaves are admixed with one another.

### Claim 3 (depends on 2)

The method of claim 2, wherein the black ginseng concentrate is produced by a process comprising
(1) steaming ginseng followed by drying to prepare red ginseng;
(2) carrying out extraction by adding water in an amount of 7 to 9 times (v/w) a black ginseng mixture containing, based on the total weight of black ginseng mixture, 48 to 52% by weight of black ginseng, 18 to 22% by weight of Patrinia scabiosaefolia roots, 18 to 22% by weight of Persicaria hydropiper leaves, and 8 to 12% by weight of Persicaria thunbergii leaves followed by filtration to prepare a mixed plant extract;
(3) having the red ginseng, which is prepared in the step (1), immersed for 2 to 4 hours at 45 to 55° C. in the mixed plant extract prepared in the step (2) followed by recovering the red ginseng from the extract;
(4) placing the red ginseng recovered in the step (3) in a steaming dryer followed by repeating 7 to 9 times a process of steaming, cooling, and drying to prepare black ginseng;
(5) carrying out extraction of crushed black ginseng, which is obtained by crushing the black ginseng prepared in the step (4), by adding alcohol followed by filtration to prepare a black ginseng extract; and
(6) concentrating at 50 to 60° ° C. the black ginseng extract prepared in the step (5) by using an evaporative concentrator to a Brix value of 67 to 71 followed by heat treatment for 5 to 7 hours at 85 to 95° C.

### Claim 4 (depends on 3)

The method of claim 3, wherein the black ginseng concentrate is produced by a process comprising:
(1) steaming ginseng for 1 to 3 hours at 90 to 110° C. and drying the steamed ginseng to obtain a red ginseng having moisture content of not more than 12 to 18% (v/w) at 45 to 55° C.;
(2) carrying out extraction for 1 to 3 hours at 80 to 90° C. by adding water in an amount of 7 to 9 times (v/w) a black ginseng mixture containing, based on the total weight of black ginseng mixture, 48 to 52% by weight of black ginseng, 18 to 22% by weight of Patrinia scabiosaefolia roots, 18 to 22% by weight of Persicaria hydropiper leaves, and 8 to 12% by weight of Persicaria thunbergii leaves followed by filtration to prepare a mixed plant extract;
(3) having the red ginseng, which is prepared in the step (1), immersed for 2 to 4 hours at 45 to 55° C. in the mixed plant extract prepared in the step (2) followed by recovering the red ginseng from the extract;
(4) placing the red ginseng recovered in the step (3) in a steaming dryer followed by repeating 7 to 9 times a process of steaming, cooling, and drying to prepare black ginseng;
(5) carrying out extraction for 1 to 3 hours at 55 to 60° C. of crushed black ginseng, which is obtained by crushing the black ginseng prepared in the step (4), by adding 60 to 80% (v/v) alcohol in an amount of 7 to 9 times (v/w) the crushed black ginseng followed by filtration to prepare a black ginseng extract; and
(6) concentrating at 50 to 60° ° C. the black ginseng extract prepared in the step (5) by using an evaporative concentrator to a Brix value of 67 to 71 followed by heat treatment for 5 to 7 hours at 85 to 95° C.

### Claim 5 (depends on 4)

The method of claim 4, wherein the black ginseng of the step (4) is prepared by, after adding the red ginseng to a steaming dryer, repeating 7 to 9 times the following process of steaming, cooling, and drying including:
maintaining the red ginseng for 60 to 90 minutes at temperature of 50 to 55° ° C. and humidity of 90 to 95%;
steaming the red ginseng for 4 to 8 hours at temperature of 90 to 95° C. and humidity of 90 to 95%;
cooling the steamed red ginseng for 60 to 90 minutes at humidity of 90 to 95% to temperature of 45 to 55° C., then cooling for 60 to 90 minutes at humidity of 90 to 95% to temperature of 25 to 30° C.; and
drying at 50 to 55° C. while no moisture is supplied to the steaming dryer.

### Claim 6 (depends on 1)

Black ginseng concentrate prepared by the method of claim 1.