# US 12,004,515 B2 · Use of a grape extract as a virucide against viruses of the coronavirus family

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- Number: US 12,004,515 B2
- Document ID: US12004515B2
- Status: Granted
- Kind: B2
- Application number: 17/684,476
- Filed: 2022-03-02
- Published: 2022-09-08
- Granted: 2024-06-11
- Earliest claimed: 2021-03-03
- Assignees: Berkem Developpement
- Applicants: Berkem Developpement
- Inventors: Daouïa Messaoudi; Olivier Fahy; Jean-Louis Peron; Jean Nkiliza
- Web page: https://patentgrep.com/patent/US12004515B2

## CPC

- A01N 65/08: Magnoliopsida [dicotyledons]
- A01N 43/16: with oxygen as the ring hetero atom
- A01P 1/00: Disinfectants; Antimicrobial compounds or mixtures thereof
- A61K 8/9789: Magnoliopsida [dicotyledons]
- A61Q 17/005: {Antimicrobial preparations}
- Y02A 50/30: Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
- A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01P: BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- Y02A: TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE

## Abstract

The present invention is from the field of disinfection and antisepsis and relates more particularly to the use of a grape extract as a virucide against viruses of the coronavirus family, adenovirus family, murine norovirus family, vaccinia virus family and poliovirus family.

## Claims

### Claim 1

A method of disinfecting an inert surface by inactivating or destroying viruses on the inert surface, comprising,
contacting the viruses with a disinfectant composition comprising a grape extract, wherein the viruses are
SARS-Cov-2 coronaviruses,
alpha coronaviruses type 229E coronavirus (HCoV-229E) or NL63 coronavirus (HCoV-NL63), or
beta coronaviruses type HCoV-OC43 or HCoV-HKU1,
and wherein the disinfectant composition inactivates or destroys the viruses.

### Claim 2 (depends on 1)

The method according to claim 1, wherein the grape extract is an extract of seeds of the species Vitis vinifera L.

### Claim 3 (depends on 1)

The method according to claim 1, wherein the inert surface is chosen from a floor, furniture, an object, or an instrument.