# US 12,002,065 B2 · Systems and methods for management of thrombosis > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,002,065 B2 - Document ID: US12002065B2 - Status: Granted - Kind: B2 - Application number: 17/130,586 - Filed: 2020-12-22 - Published: 2021-04-15 - Granted: 2024-06-04 - Earliest claimed: 2014-04-08 - Assignees: Incuvate, LLC - Applicants: Incuvate, LLC - Inventors: David M. Look; Bradley S. Culbert - Web page: https://patentgrep.com/patent/US12002065B2 ## CPC - G06Q 30/0207: Discounts or incentives, e.g. coupons or rebates - A61B 17/22: Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for - A61B 17/32037: {for removing obstructions from inner organs or blood vessels, e.g. for atherectomy} - A61M 1/90: {Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing} - G06Q 30/02: Marketing; Price estimation or determination; Fundraising - G06Q 30/0601: Electronic shopping [e-shopping] - A61B 2017/00022: {Sensing or detecting at the treatment site} - A61B 2017/00119: {alarm; indicating an abnormal situation} - A61B 2017/00991: {Telescopic means} - A61B 2017/22001: {Angioplasty, e.g. PCTA} - A61B 2017/22039: {eccentric} - A61B 2017/22067: {Blocking; Occlusion (A61B2017/22054 takes precedence)} - A61B 2017/22079: {with suction of debris} - A61B 2017/22094: {for crossing total occlusions, i.e. piercing} - A61B 2217/005: with suction drainage system - G06Q: INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract An aspiration system includes an elongate tubular member having a lumen; an aspiration catheter configured to be inserted through the lumen of the elongate tubular member, and including a tubular aspiration member having a proximal end, a distal end, and a lumen, and configured to at least partially extend out of the lumen of the elongate tubular member at the distal end of the elongate tubular member; an elongate support member coupled to the tubular aspiration member and extending between a proximal end of the aspiration catheter and the proximal end of the tubular aspiration member; and an annular sealing member coupled to the tubular aspiration member and configured to create a seal against an inner surface of the elongate tubular member, when a vacuum sufficient to cause aspiration is actively applied to the lumen of the elongate tubular member. ## Claims ### Claim 1 An aspiration catheter comprising: a proximal end; a distal end configured to be inserted through a lumen of a guiding catheter and into the vasculature of a patient; a tubular aspiration member having a proximal end, a distal end, and a lumen; an elongate support member coupled to the tubular aspiration member and extending between the proximal end of the aspiration catheter and the proximal end of the tubular aspiration member, the elongate support member from the proximal end of the aspiration catheter until the proximal end of the tubular aspiration member having a relatively small diameter in relation to the lumen of the tubular aspiration member; and an annular sealing surface coupled to the tubular aspiration member and configured to form an annular seal against the inner surface of the guiding catheter. ### Claim 2 (depends on 1) The aspiration catheter of claim 1, wherein the annular sealing surface is not on an inflatable balloon. ### Claim 3 (depends on 1) The aspiration catheter of claim 1, wherein the annular sealing surface is not expandable by a user. ### Claim 4 (depends on 1) The aspiration catheter of claim 1, wherein the annular sealing surface comprises a lip. ### Claim 5 (depends on 1) The aspiration catheter of claim 1, wherein the annular sealing surface comprises a flare. ### Claim 6 (depends on 1) The aspiration catheter of claim 1, wherein the annular sealing surface is on an elastomeric ring. ### Claim 7 (depends on 1) The aspiration catheter of claim 1, wherein the annular sealing surface comprises a hydrogel. ### Claim 8 (depends on 1) The aspiration catheter of claim 1, further comprising: a hub coupled to the elongate support member at its proximal end. ### Claim 9 (depends on 1) The aspiration catheter of claim 1, further comprising: a high pressure injection lumen having a proximal end and a distal end and extending along the elongate support member; and at least one orifice at or near the distal end of the high pressure injection lumen and configured to allow high pressure liquid injected through the high pressure injection lumen to enter the lumen of the tubular aspiration member. ### Claim 10 (depends on 9) The aspiration catheter of claim 9, further comprising: a hub coupled to the elongate support member, wherein the hub is configured to be decoupled from the high pressure injection lumen of the elongate support member. ### Claim 11 An aspiration catheter comprising: a proximal end; a distal end configured to be inserted through a lumen of a guiding catheter and into the vasculature of a patient; a tubular aspiration member having a proximal end, a distal end, and a lumen; an elongate support member coupled to the tubular aspiration member and extending proximally from the proximal end of the tubular aspiration member, the elongate support member along the entirety of its length having a relatively small diameter in relation to the lumen of the tubular aspiration member, the elongate support member at the relatively small diameter configured to be sealed by a hemostatic valve of a y-connector; and an annular sealing surface coupled to the tubular aspiration member and configured to form an annular seal against the inner surface of the guiding catheter. ### Claim 12 (depends on 11) The aspiration catheter of claim 11, wherein the annular sealing surface is not on an inflatable balloon. ### Claim 13 (depends on 11) The aspiration catheter of claim 11, wherein the annular sealing surface is not expandable by a user. ### Claim 14 (depends on 11) The aspiration catheter of claim 11, wherein the annular sealing surface comprises a lip. ### Claim 15 (depends on 11) The aspiration catheter of claim 11, wherein the annular sealing surface comprises a flare. ### Claim 16 (depends on 11) The aspiration catheter of claim 11, wherein the annular sealing surface is on an elastomeric ring. ### Claim 17 (depends on 11) The aspiration catheter of claim 11, wherein the annular sealing surface comprises a hydrogel. ### Claim 18 (depends on 11) The aspiration catheter of claim 11, further comprising: a hub coupled to the elongate support member at its proximal end. ### Claim 19 (depends on 11) The aspiration catheter of claim 11, further comprising: a high pressure injection lumen having a proximal end and a distal end and extending along the elongate support member; and at least one orifice at or near the distal end of the high pressure injection lumen and configured to allow high pressure liquid injected through the high pressure injection lumen to enter the lumen of the tubular aspiration member. ### Claim 20 (depends on 19) The aspiration catheter of claim 19, further comprising: a hub coupled to the elongate support member, wherein the hub is configured to be decoupled from the high pressure injection lumen of the elongate support member.