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US 12,000,791 B2Granted
RNA profiling device and method
AssigneeUniversiti Malaya
InventorsVengadesh Periasamy, Maryam Rajabpour Niknam, Nastaran Rizan, Sara Talebi
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Abstract
The present invention provides device for profiling a biological sample with at least one RNA segment comprising: a metal wire positioned relative to the biological sample such that the sample and the metal wire form a Schottky barrier junction; a bias voltage provider adapted for rectifying the Schottky junction; and; a module for collecting the current over voltage profile of the Schottky junction.
Claims17
A device configured to generate an electrical signal profile of a ribonucleic acid (RNA) segment in a biological sample, the device comprising:
- a metal wire positioned adjacent to the RNA containing biological sample such that the RNA containing biological sample and the metal wire form a Schottky barrier junction;
- a bias voltage provider to rectify the Schottky barrier junction formed by the RNA containing biological sample and the metal wire;
- and
- a module configured to collect a current over voltage profile of the Schottky barrier junction formed by the RNA containing biological sample and the metal wire, wherein the device is an RNA detection/identifying kit, and depending on a type of RNA segment being profiled, the Schottky barrier junction formed by the RNA containing biological sample and the metal wire is a p-n junction or a n-p junction.
1 more element
A method comprising:
- generating, by an electronic device, an electrical signal profile of a ribonucleic acid (RNA) segment in a biological sample,
- wherein the method of generating, by the electronic device, the electrical signal profile of the RNA segment includes the following method steps;
- providing a metal wire adjacent to the RNA segment, in a manner such that the metal wire and the RNA segment form a Schottky barrier junction;
- providing a bias voltage to the Schottky barrier junction;
- and
- collecting a current over voltage profile of the Schottky barrier junction, wherein the device is an RNA detection/identifying kit, and depending on a type of RNA segment being profiled, the Schottky barrier junction is a p-n junction or a n-p junction.
3 more elements
Dependencies are inferred from the claim text.