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US 11,999,975 B2Granted
Method for purifying an enveloped virus
AssigneeProbiogen AG
InventorsVolker Sandig, Michael Mühle, Sven Krügener
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Abstract
The present invention relates to a method for purifying an enveloped virus. The present invention further relates to an enveloped virus or a plurality of enveloped viruses obtainable by said method.
Claims7
A method for purifying an enveloped virus comprising the steps of:
- (i) binding an enveloped virus comprised in a preparation to a mixed mode chromatography carrier, and
- (ii) eluting the enveloped virus from the mixed mode chromatography carrier with an elution buffer, wherein the mixed mode chromatography carrier is a hydrophobic ion exchange chromatography carrier and wherein the elution buffer comprises arginine.
Dependencies are inferred from the claim text.