# US 11,999,707 B1 · N′-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)-1-naphthimidamide as an antimicrobial compound

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- Number: US 11,999,707 B1
- Document ID: US11999707B1
- Status: Granted
- Kind: B1
- Application number: 18/427,924
- Filed: 2024-01-31
- Granted: 2024-06-04
- Earliest claimed: 2023-10-11
- Assignees: King Faisal University
- Applicants: King Faisal University
- Inventors: Mai Mostafa Khalaf Ali; Hany Mohamed Abd El-Lateef Ahmed; Antar Ahmed Abdelhamid Ahmed; Amer A. Amer
- Web page: https://patentgrep.com/patent/US11999707B1

## CPC

- C07D 271/113: with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
- A61P 31/04: Antibacterial agents
- A61P 31/10: Antimycotics
- C07D: HETEROCYCLIC COMPOUNDS (macromolecular compounds C08)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

A N′-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)-1-naphthimidamide compound, its synthesis, and its use as an antimicrobial agent.

## Claims

### Claim 1

A method of treating a microbial infection in a patient comprising administering to a patient in need thereof a therapeutically effective amount of a N′-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)-1-naphthimidamide compound having the formula I:

### Claim 2 (depends on 1)

The method of treating the microbial infection of claim 1, wherein the microbial infection is caused by one or more bacteria or fungi.

### Claim 3 (depends on 2)

The method of treating the microbial infection of claim 2, wherein the microbial infection is caused by one or more gram positive bacteria, one or more gram negative bacteria, one or more fungi, or a combination thereof.

### Claim 4 (depends on 3)

The method of treating the microbial infection of claim 3, wherein the one or more gram positive bacteria are Bacillus cereus, Staphylococcus aureus, or a combination thereof.

### Claim 5 (depends on 3)

The method of treating the microbial infection of claim 3, wherein the one or more gram negative bacteria are Pseudomonas aeruginosa, Escherichia coli, or a combination thereof.

### Claim 6 (depends on 2)

The method of treating the microbial infection of claim 2, wherein the one or more fungi are Aspergillus flavus, Chrysosporium keratinophilum, or a combination thereof.