# US 11,999,705 B1 · 4-chloro-N′-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)benzimidamide as an antimicrobial compound

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- Number: US 11,999,705 B1
- Document ID: US11999705B1
- Status: Granted
- Kind: B1
- Application number: 18/428,797
- Filed: 2024-01-31
- Granted: 2024-06-04
- Earliest claimed: 2023-10-13
- Assignees: King Faisal University
- Applicants: King Faisal University
- Inventors: Hany Mohamed Abd El-Lateef Ahmed; Mai Mostafa Khalaf Ali; Antar Ahmed Abdelhamid Ahmed; Amer A. Amer
- Web page: https://patentgrep.com/patent/US11999705B1

## CPC

- C07D 271/10: 1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
- A61P 31/04: Antibacterial agents
- A61P 31/10: Antimycotics
- C07D 271/06: 1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
- C07B 2200/13: Crystalline forms, e.g. polymorphs
- C07D: HETEROCYCLIC COMPOUNDS (macromolecular compounds C08)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- C07B: GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR (preparation of carboxylic acid esters by telomerisation C07C67/47; telomerisation C08F)

## Abstract

A 4-chloro-N′-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)benzimidamide compound, its synthesis, and its use as an antimicrobial agent.

## Claims

### Claim 1

A method of treating a microbial infection in a patient comprising administering to a patient in need thereof a therapeutically effective amount of a 4-chloro-N′-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)benzimidamide compound, wherein the microbial infection is caused by one or more gram positive bacteria, one or more gram negative bacteria, or one or more fungi, or a combination thereof.

### Claim 2 (depends on 1)

The method of treating the microbial infection of claim 1, wherein the one or more gram positive bacteria are Bacillus cereus, or Staphylococcus aureus, or a combination thereof.

### Claim 3 (depends on 1)

The method of treating the microbial infection of claim 1, wherein the one or more gram negative bacteria are Pseudomonas aeruginosa, or Escherichia coli, or a combination thereof.

### Claim 4 (depends on 1)

The method of treating the microbial infection of claim 1, wherein the one or more fungi are Aspergillus flavus, or Chrysosporium keratinophilum, or a combination thereof.