Back to results
US 11,998,901 B2Granted
Metal complex, method for producing same, and method for producing gamma-lactam compound using same
AssigneesInstitute for Basic Science, Korea Advanced Institute of Science and Technology
InventorsSukbok Chang, Seung Youn Hong, Yoon Su Park, Yeongyu Hwang, Yeong Bum Kim
Life of this patent
Estimating the term…
Abstract
The present invention relates to a novel metal complex, a method for producing same, and a method for producing a gamma-lactam compound using same, and the metal complex according to the present invention is used as a catalyst for producing a gamma-lactam compound and can efficiently produce a gamma-lactam compound with an excellent yield and excellent selectivity.
Claims12
A method of preparing a gamma-lactam compound, the method comprising:
- amidating a dioxazol-one compound in the presence of a metal complex represented by the following Chemical Formula 1 and a base to prepare the gamma-lactam compound:
- wherein
- M is iridium, rhodium, ruthenium, or cobalt;
- L is
- X is a halogen;
- R1, R2, R3, R4 and R5 are independently of one another hydrogen or (C1-C20)alkyl;
- and
- R6 is a halogen, (C1-C20)alkyl, halo(C1-C20)alkyl, (C1-C20)alkoxy, (C6-C20)aryl, or (C3-C20)heteroaryl;
- A is —CO— or —SO2—;
- R7 is (C1-C20)alkyl, (C1-C20)alkoxy, (C6-C20)aryl, (C1-C20)alkyl(C6-C20)aryl, or —NR11R12;
- R11 and R12 are independently of each other hydrogen or (C1-C20)alkyl;
- and
- n is an integer of 0 to 6.
10 more elements
Dependencies are inferred from the claim text.