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US 11,998,890 B2Granted
Functionalised chromatography medium comprising polymer nanofibres and process of preparation thereof
AssigneePuridify Ltd.
InventorsMarc Hummersone, Benjamin Wallis, Frederic Leroux, William Law
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Abstract
Functionalised polymeric chromatography medium, comprising: at least one non-woven sheet comprising one or more polymeric nanofibers having a mean diameter of 10-1000 nm; one or more polymer chains grafted onto the one or more polymeric nanofibers, wherein the polymer chains are poly-glycerol chains comprising glycidol monomer residues or wherein the polymer chains comprise divinylsulfone monomer residues; and at least one ligand group bonded to the one or more polymer chains.
Claims26
A functionalized chromatography medium, comprising
- i) at least one non-woven sheet comprising one or more polymeric nanofibers, said nanofibers having a mean diameter of 10-1000 nm;
- ii) one or more polymer chains grafted onto the one or more polymeric nanofibers, wherein the polymer chains are poly-glycerol chains comprising glycidol monomer residues or wherein the polymer chains comprise divinylsulfone monomer residues;
- and
- iii) at least one ligand group bonded to the one or more polymer chains;
- wherein the polymer chains are grown on the polymeric nanofibers.
2 more elements
Dependencies are inferred from the claim text.