# US 11,998,753 B2 · Wireless neural stimulator with injectable

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- Number: US 11,998,753 B2
- Document ID: US11998753B2
- Status: Granted
- Kind: B2
- Application number: 16/991,593
- Filed: 2020-08-12
- Published: 2021-01-28
- Granted: 2024-06-04
- Earliest claimed: 2016-10-16
- Assignees: StimAire, Inc.
- Applicants: StimAire, Inc.
- Inventors: Tarek Makansi
- Web page: https://patentgrep.com/patent/US11998753B2

## CPC

- A61N 1/3605: {Implantable neurostimulators for stimulating central or peripheral nerve system}
- A61N 2/02: using magnetic fields produced by coils, including single turn loops or electromagnets (A61N2/12 takes precedence)
- A61N 1/37205: {Microstimulators, e.g. implantable through a cannula}
- A61N 1/3787: {from an external energy source}
- A61N 1/40: Applying electric fields by inductive or capacitive coupling (microwave apparatus A61N5/00); {Applying radio-frequency signals}
- A61N 2/006: {for magnetic stimulation of nerve tissue}
- A61N 2/008: {for pain treatment or analgesia}
- A61N 1/36125: {Details of circuitry or electric components}
- A61N 1/37223: {Circuits for electromagnetic coupling}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)

## Abstract

Neural stimulator systems with an external magnetic coil to produce changing magnetic fields is applied outside the body, in conjunction with one or more tiny injectable objects that concentrates the induced electric field to a highly-targeted location. These systems include a driver circuit for the magnetic coil that allows for high voltage and fast pulses in the coil, while requiring low-voltage power supply that may be powered by a wearable or portable external device, along with the coil and driver circuit.

## Claims

### Claim 1

A neuromodulation system, comprising:
an external free running resonance magnetic field generator, comprising:
a housing;
a coil;
a capacitor connected in parallel with the coil such that a stimulation signal is a portion in time of a resonance between the parallel capacitor and coil;
a DC power supply at a first side of the parallel capacitor and coil, and configured to activate the parallel coil and capacitor; and
a switch to ground on a second side of the parallel capacitor and coil, wherein the switch comprises a microprocessor, a transistor and a rectifier;
wherein the microprocessor is configured to turn off a gate or a base of the transistor just prior to a first series of decaying resonant pulses to provide a free running resonance between the coil and the capacitor and then turn on the gate or the base to build up a current in the magnetic field generator prior to a second series of decaying resonant pulses to reduce electrical energy in the coil between the first and second series.

### Claim 2 (depends on 1)

The neuromodulation system of claim 1, wherein the magnetic field generator further comprises an adhesive to attach the housing to a location on a human body.

### Claim 3 (depends on 1)

The neuromodulation system of claim 1, further comprising a means for attaching the housing to a location on a human body.

### Claim 4 (depends on 1)

The neuromodulation system of claim 1, wherein the magnetic field generator further comprises a battery.

### Claim 5 (depends on 4)

The neuromodulation system claim 4, wherein the magnetic field generator further comprises a contact sensor, and wherein the magnetic field generator is configured to turn off and save battery life when not placed against skin.

### Claim 6 (depends on 4)

The neuromodulation system of claim 4, wherein the battery is a rechargeable battery.

### Claim 7 (depends on 1)

The neuromodulation system of claim 1, wherein the coil is a flexible coil.

### Claim 8 (depends on 7)

The neuromodulation system of claim 7, wherein the flexible coil comprises a flexible circuit board.

### Claim 9 (depends on 7)

The neuromodulation system of claim 7, wherein the flexible coil comprises a flexible material selected from a group consisting of BoPET, polyethylene, polyurethane, nylon and PTFE.

### Claim 10 (depends on 7)

The neuromodulation system of claim 7, wherein the flexible coil comprises a flexible material with a thickness between 1 mm and 2 mm.

### Claim 11 (depends on 1)

The neuromodulation system of claim 1, wherein the coil is a rigid coil.

### Claim 12 (depends on 11)

The neuromodulation system of claim 11, wherein the coil has a thickness between 0.5 mm and 2.00 mm.

### Claim 13 (depends on 1)

The neuromodulation system of claim 1, wherein the coil comprises an oval cross-section, with a long side of the oval cross-section configured to face a human body.