# US 11,998,670 B2 · Disposable cartridge and pump track mechanism > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,998,670 B2 - Document ID: US11998670B2 - Status: Granted - Kind: B2 - Application number: 17/088,437 - Filed: 2020-11-03 - Published: 2021-05-06 - Granted: 2024-06-04 - Earliest claimed: 2019-11-05 - Assignees: Diality Inc. - Applicants: Diality Inc. - Inventors: Andres Dandler; Clayton Poppe; Miroslav Mitrovic - Web page: https://patentgrep.com/patent/US11998670B2 ## CPC - A61M 1/155: {with treatment-fluid pumping means or components thereof} - A61M 1/152: {Details related to the interface between cassette and machine} - A61M 1/1524: {the interface providing means for actuating on functional elements of the cassette, e.g. plungers} - A61M 1/156: {Constructional details of the cassette, e.g. specific details on material or shape} - A61M 1/16: with membranes - A61M 1/1621: {Constructional aspects thereof (semi-permeable membranes for separation processes characterised by their properties B01D69/00; semi permeable membranes characterised by their material B01D71/00)} - A61M 1/262: {rotating} - A61M 1/36222: {Details related to the interface between cassette and machine} - A61M 1/362227: {the interface providing means for actuating on functional elements of the cassette, e.g. plungers} - A61M 1/36225: {with blood pumping means or components thereof} - A61M 39/10: Tube connectors or tube couplings - A61M 60/109: incorporated within extracorporeal blood circuits or systems - A61M 60/279: Peristaltic pumps, e.g. roller pumps - A61M 60/37: Haemodialysis, haemofiltration or diafiltration - A61M 60/438: the force acting on the blood contacting member being mechanical - A61M 60/835: of positive displacement blood pumps - A61M 60/847: arranged in a cassette - F16L 21/08: with additional locking means (F16L21/06 takes precedence; couplings of the quick-acting type F16L37/00) - F16L 37/08: in which the connection between abutting or axially overlapping ends is maintained by locking members (F16L37/22 - F16L37/26 take precedence) - F16L 37/14: Joints secured by inserting between mating surfaces an element, e.g. a piece of wire, a pin, a chain - A61M 1/1522: {the interface being evacuated interfaces to enhance contact} - A61M 1/154: {with sensing means or components thereof} - A61M 2205/12: with interchangeable cassettes forming partially or totally the fluid circuit - A61M 2205/121: interface between cassette and base - A61M 2205/127: with provisions for heating or cooling - A61M 2205/332: Force measuring means - A61M 2205/58: Means for facilitating use, e.g. by people with impaired vision - A61M 2205/702: automatically during use - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} - F16L: PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL ## Abstract Disclosed are example embodiments of a dialysis machine having a frame, a cartridge cassette, one or more alignment-locking features, and an actuation mechanism. The frame is fixedly coupled to the dialysis machine, and the cassette is slidably coupled to the frame. The cassette can have one or more track structures, with each of the one or more track structures having a rotor and one or more rollers. The one or more alignment-locking features extend from the frame and are configured to be inserted into one or more alignment features of a disposable cartridge that functions to secure or release the disposable cartridge. The actuation mechanism is made to slide the cassette with respect to the one or more track structures. ## Claims ### Claim 1 A dialysis system comprising: a dialysis machine and a disposable cartridge; said dialysis machine including, a frame fixedly coupled to the dialysis machine; a cassette slidably coupled to the frame, the cassette comprises three track structures, wherein each of the three track structures comprises a rotor and one or more rollers; one or more alignment-locking features extending from the frame, the one or more alignment-locking features configured to be inserted into one or more alignment features of a disposable cartridge and secure or release the disposable cartridge; and an actuation mechanism configured to slide the cassette with respect to the one or more track structures and to actuate the one or more alignment-locking features to either secure or release the disposable cartridge; and said disposable cartridge including, a housing having two or more alignment features; and wherein the two or more alignment features are configured to receive an alignment- locking feature from the dialysis machine, wherein the alignment-locking feature is configured to pull the housing into the dialysis machine and secure the housing; and a first, a second, and a third tubing lines mounted on the housing, wherein each tubing line comprises a U-shape section configured to fall into a recessed track of the dialysis machine. ### Claim 2 (depends on 1) The dialysis system of claim 1 wherein each of the two or more alignment features comprises a slot or a hole. ### Claim 3 (depends on 1) The dialysis system of claim 1 wherein the disposable cartridge's alignment-locking feature comprises a pin having actuatable side fingers. ### Claim 4 (depends on 3) The dialysis system of claim 3 said actuatable side fingers of the pin are configured to extend outward to grab onto the housing of the disposable cartridge when a pull-rod of the pin is pulled away from the housing. ### Claim 5 (depends on 3) The dialysis system of claim 3 said actuatable side fingers of the pin are configured to fold inward when a pull-rod of the pin is pushed forward toward the housing. ### Claim 6 (depends on 3) The dialysis system of claim 3 wherein said dialysis machine's actuation mechanism is configured to push the pin forward and retract the side fingers when it is set to a lock state. ### Claim 7 (depends on 3) The dialysis system of claim 3 wherein said dialysis machine's actuation mechanism is configured to pull the pin backward and expand the side fingers when it is set to an open state. ### Claim 8 (depends on 1) The dialysis system of claim 1 wherein said cassette's three tracks are recessed. ### Claim 9 (depends on 1) The dialysis system of claim 1 wherein said dialysis machine's actuation mechanism is configured to slide the cassette inward and push the three tubing lines against a roller when the actuation mechanism is set to a lock state. ### Claim 10 (depends on 1) The dialysis system of claim 1 wherein said dialysis machine's actuation mechanism is configured to slide the cassette outward to release pressure on the tubing lines when it is set to an open state. ### Claim 11 (depends on 1) The dialysis system of claim 1 wherein said dialysis machine's actuation mechanism comprises a linkage assembly configured to translate the cassette while the frame remains stationary and to actuate the one or more alignment-locking features to lock or release the disposable cartridge. ### Claim 12 (depends on 11) The dialysis system of claim 11 wherein said linkage assembly is configured to slide the cassette inward and push each tubing line against a pump motor when it is set to a lock state. ### Claim 13 (depends on 11) The dialysis system of claim 11 wherein said linkage assembly is configured to slide the cassette outward to release pressure on the tubing lines when it is set to an open state. ### Claim 14 (depends on 11) The dialysis system of claim 11 wherein said linkage assembly is configured to push the pin forward and retract the side fingers when it is set to a lock state. ### Claim 15 (depends on 11) The dialysis system of claim 11 wherein said linkage assembly is configured to pull the pin backward and expand the side fingers when it is set to an open state. ### Claim 16 (depends on 1) The dialysis system of claim 1 wherein said dialysis machine's actuation mechanism comprises: a lever coupled to a first shaft, a first cam coupled to the first shaft; a plurality of linkages coupled to the first cam; and a sliding element coupled to the plurality of linkages and to the cassette, and wherein the plurality of linkages are arranged such the cassette is slid inward or outward when the lever is actuated. ### Claim 17 (depends on 16) The dialysis system of claim 16 wherein said dialysis machine's actuation mechanism further comprises: a gear assembly coupled to the first shaft; a second shaft coupled to the gear assembly; a second cam coupled to the second shaft; and a pull-plate coupled to the second cam and to the pin, wherein the pull-plate and the pin are concurrently actuated forward or backward when the lever is actuated. ### Claim 18 (depends on 1) The dialysis system of claim 1 wherein said dialysis machine's actuation mechanism comprises: a first set of one or more motors configured to slide the cassette with respect to the three track structures; and a second set of one or more motors configured to actuate the one or more alignment-locking features to either secure or release the disposable cartridge.