# US 11,998,365 B2 · System and method for diagnostic analysis of human body systems, organs, and cells

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- Number: US 11,998,365 B2
- Document ID: US11998365B2
- Status: Granted
- Kind: B2
- Application number: 17/465,674
- Filed: 2021-09-02
- Published: 2021-12-23
- Granted: 2024-06-04
- Earliest claimed: 2019-07-23
- Assignees: KMZ Holdings LLC
- Applicants: KMZ Holdings LLC
- Inventors: Nandan Kundetkar
- Web page: https://patentgrep.com/patent/US11998365B2

## CPC

- A61B 5/7275: {Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor}
- A61B 5/0507: using microwaves or terahertz waves
- A61B 5/7257: {using Fourier transforms}
- G16H 50/20: for computer-aided diagnosis, e.g. based on medical expert systems
- A61B 5/02108: {from analysis of pulse wave characteristics}
- A61B 5/7203: {for noise prevention, reduction or removal}
- A61B 5/7228: {Signal modulation applied to the input signal sent to patient or subject; Demodulation to recover the physiological signal}
- A61B 5/7246: {using correlation, e.g. template matching or determination of similarity}
- A61B 5/725: {using specific filters therefor, e.g. Kalman or adaptive filters (specific diagnostics methods using using bioelectric or biomagnetic signals A61B5/316)}
- G16H 10/60: for patient-specific data, e.g. for electronic patient records
- G16H 15/00: ICT specially adapted for medical reports, e.g. generation or transmission thereof
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA

## Abstract

A system and method for providing diagnostic analysis of a physical condition of a human body. A signal generator, an emitter, a receiver, and processor(s) generate a baseline signal. In some implementations, the emitter may emit the baseline signal through cells of the human body over scanning points for a predetermined amount of time, and a receiver detects reflected signals that have propagated through the cells of the human body. Some implementations include determining, by the one or more processors, a power spectrum density (PSD) of the reflected baseline signal and a spectral variance in the PSD of the reflected baseline signal relative to the baseline signal. Some implementations may compare the spectral variance to one or more predetermined spectral variances corresponding to one or more conditions of the human body and determine the condition of the human body, based on the comparison.

## Claims

### Claim 1

A system for providing diagnostic analysis of a physical condition of a human body, the system comprising:
a signal generator;
an emitter;
a receiver; and
one or more processors in communication with a memory having non-transitory computer readable instructions stored thereon, that when executed by the one or more processors cause the system to:
generate, by the signal generator, a baseline signal;
emit, by the emitter, the baseline signal through one or more cells of the human body over a plurality of scanning points for a predetermined amount of time;
receive, by the receiver, one or more reflected signals that have propagated through the one or more cells of the human body, wherein the receiver is configured to detect magnetic field perturbations;
determine, by the one or more processors, a power spectrum density (PSD) of the reflected baseline signal;
determine, by the one or more processors, a spectral variance in the PSD of the reflected baseline signal relative to the baseline signal;
compare, by the one or more processors, the spectral variance to one or more predetermined spectral variances corresponding to one or more physical conditions of the human body;
determine, by the one or more processors and based on the comparison, the physical condition of the human body, wherein the determined physical condition is determinable based on biological conditions of the human body; and
transmit a report indicating the physical condition of the human body.

### Claim 2 (depends on 1)

The system of claim 1, wherein determining the spectral variance in the PSD comprises determining an amplitude and phase shift of the reflected signal relative to the baseline signal.

### Claim 3 (depends on 1)

The system of claim 1, wherein the signal generator, the emitter, and the receiver comprise a wireless handheld device.

### Claim 4 (depends on 1)

The system of claim 1, wherein the emitter and the receiver are coupled to a dielectric.

### Claim 5 (depends on 1)

The system of claim 1, wherein the signal generator comprises a dual phase lock loop (PLL) clock generator having an operating range of at least 14 GHz.

### Claim 6 (depends on 1)

The system of claim 1, wherein the predetermined amount of time is no more than 100 seconds.

### Claim 7 (depends on 1)

The system of claim 1, wherein the baseline signal comprises a first carrier signal corresponding to a primary baseline signal and a second carrier signal corresponding to an identifier.

### Claim 8 (depends on 7)

The system of claim 7, wherein the identifier comprises a frequency shift key (FSK) and phase shift key (PSK) of the baseline signal.

### Claim 9 (depends on 1)

The system of claim 1, wherein the plurality of scanning points comprises at least 2 billion data points.

### Claim 10 (depends on 1)

The system of claim 1, wherein the magnetic field perturbations correspond to at least a portion of the reflected signal in an order of magnitude corresponding to one Nano Gauss or smaller.

### Claim 11 (depends on 1)

The system of claim 1, wherein the one or more processors comprise a remote computing device having a display.

### Claim 12 (depends on 1)

The system of claim 1, wherein transmitting the report comprises rendering on the display at least one of: an indication of the PSD of the reflected baselines, an indication of the spectral variance, or an indication of the determined physical condition of the human body on the display.

### Claim 13

A method for providing diagnostic analysis of a physical condition of a human body utilizing a system comprising: a signal generator, an emitter, a receiver, and one or more processors in communication with a memory having non-transitory computer readable instructions stored thereon, that when executed by the one or more processors cause the system to execute the method, the method comprising:
generating, by the signal generator, a baseline signal;
emitting, by the emitter, the baseline signal through one or more cells of the human body over a plurality of scanning points for a predetermined amount of time;
receiving, by the receiver, one or more reflected signals that have propagated through the one or more cells of the human body, wherein the receiver is configured to detect magnetic field perturbations;
determining, by the one or more processors, a power spectrum density (PSD) of the reflected baseline signal;
determining, by the one or more processors, a spectral variance in the PSD of the reflected baseline signal relative to the baseline signal;
comparing, by the one or more processors, the spectral variance to one or more predetermined spectral variances corresponding to one or more physical conditions of the human body;
determining, by the one or more processors and based on the comparison, the physical condition of the human body, wherein the determined physical condition is determinable based on biological conditions of the human body; and
transmitting a report indicating the physical condition of the human body.

### Claim 14 (depends on 13)

The method of claim 13, wherein determining the spectral variance in the PSD comprises determining an amplitude and phase shift of the reflected signal relative to the baseline signal.

### Claim 15 (depends on 13)

The method of claim 13, wherein the signal generator, the emitter, and the receiver comprise a wireless handheld device.

### Claim 16 (depends on 13)

The method of claim 13, wherein the emitter and the receiver are coupled to a dielectric.

### Claim 17 (depends on 13)

The method of claim 13, wherein the signal generator comprises a dual phase lock loop (PLL) clock generator having an operating range of at least 14 GHz.

### Claim 18 (depends on 13)

The method of claim 13, wherein the predetermined amount of time is no more than 100 seconds.

### Claim 19 (depends on 13)

The method of claim 13, wherein the baseline signal comprises a first carrier signal corresponding to the baseline signal and a second carrier signal corresponding to an identifier.

### Claim 20 (depends on 19)

The method of claim 19, wherein the identifier comprises a frequency shift key (FSK) and phase shift key (PSK) of the baseline signal.

### Claim 21 (depends on 13)

The method of claim 13, wherein the plurality of scanning points comprises at least 2 billion data points.

### Claim 22 (depends on 13)

The method of claim 13, wherein the magnetic field perturbations correspond to at least a portion of the reflected signal in an order of magnitude corresponding to one Nano Gauss or smaller.

### Claim 23 (depends on 13)

The method of claim 13, wherein the one or more processors comprise a remote computing device having a display.

### Claim 24 (depends on 13)

The method of claim 13, wherein transmitting the report comprises rendering on the display at least one of: an indication of the PSD of the reflected baselines, an indication of the spectral variance, or an indication of the determined physical condition of the human body on the display.