# US 11,998,301 B2 · Systems and methods for analysis of temperature signals from an Abreu brain thermal tunnel and treatment of human conditions via the Abreu brain thermal tunnel

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- Number: US 11,998,301 B2
- Document ID: US11998301B2
- Status: Granted
- Kind: B2
- Application number: 17/963,992
- Filed: 2022-10-11
- Published: 2023-02-02
- Granted: 2024-06-04
- Earliest claimed: 2015-04-01
- Assignees: Brain Tunnelgenix Technologies Corp.
- Applicants: Brain Tunnelgenix Technologies Corp.
- Inventors: Marcio Marc Abreu
- Web page: https://patentgrep.com/patent/US11998301B2

## CPC

- A61B 5/01: Measuring temperature of body parts {; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue} (clinical contact thermometers G01K13/20)
- A61B 5/0036: {including treatment, e.g., using an implantable medical device, ablating, ventilating}
- A61B 5/4094: {Diagnosing or monitoring seizure diseases, e.g. epilepsy}
- A61B 5/6821: {Eye}
- A61B 5/7275: {Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor}
- A61B 5/746: {Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms}
- A61F 7/007: {characterised by electric heating}
- G16H 20/30: relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
- G16H 50/20: for computer-aided diagnosis, e.g. based on medical expert systems
- A61B 5/4836: {Diagnosis combined with treatment in closed-loop systems or methods (A61B5/0036 takes precedence)}
- A61B 5/6803: {Head-worn items, e.g. helmets, masks, headphones or goggles}
- A61F 2007/0004: {Eyes or part of the face surrounding the eyes}
- A61F 2007/0086: {with a thermostat}
- A61F 2007/0096: {with a thermometer}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C)
- G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA

## Abstract

Systems configured to acquire temperature signals from an Abreu Brain Thermal Tunnel (ABTT), to analyze the temperatures signals, and to determine a condition of a human body from the analysis, and a method for doing the same, are described. In addition, systems for application of thermal signals to the ABTT for treatment of conditions are described.

## Claims

### Claim 1

A thermal diagnosis and treatment apparatus, comprising:
a first temperature sensor configured to output a first temperature signal corresponding to a temperature of a first Abreu brain thermal tunnel (ABTT) terminus of a subject;
a first temperature modification device positioned adjacent to the first temperature sensor, the first temperature modification device being one of a heater, a cooler, and a combination heater and cooler;
a second temperature sensor configured to output a second temperature signal to a temperature of a second ABTT terminus of the subject, the second temperature sensor being positioned a spaced distance from the first temperature sensor, the spaced distance being equal to a distance between the first ABTT terminus and the second ABTT terminus;
a second temperature modification device positioned adjacent to the second temperature sensor the second temperature modification device being one of a heater, a cooler, and a combination heater and cooler; and
a processor configured to:
receive the first temperature signal and the second temperature signal from the subject,
determine a left-right side dominance of the subject from the first temperature signal and the second temperature signal to determine a dominant side of the subject,
determine that the dominant side has a temperature greater than 36 degrees Celsius,
control one of the first temperature modification device and the second temperature modification device that is positioned on the dominant side to reduce the temperature of one of the first temperature modification device and the second temperature modification device that is positioned on the dominant side until the temperature on the dominant side is less than or equal to 36 degrees Celsius, and maintain the temperature on the dominant side for a predetermined interval that is greater than or equal to 1 minute, and
output a notification to an output device after the predetermined interval is reached.

### Claim 2 (depends on 1)

The thermal diagnosis and treatment apparatus of claim 1, wherein the processor determines the left-right side dominance from a baseline temperature of the subject, and the processor determines the baseline temperature from the first temperature signal and the second temperature signal.

### Claim 3 (depends on 1)

The thermal diagnosis and treatment apparatus of claim 1, wherein the processor determines that a non-dominant side has a temperature greater than the temperature of the dominant side minus 0.2 degrees, and the processor controls one of the first temperature modification device and the second temperature modification device that is positioned on the non-dominant side to reduce the temperature of one of the first temperature modification device and the second temperature modification device that is positioned on the non-dominant side until the temperature on the non-dominant side is less than or equal to the temperature on the dominant side minus 0.2 degrees Celsius, and the processor maintains the temperature on the non-dominant side for the predetermined interval.

### Claim 4 (depends on 1)

The thermal diagnosis and treatment apparatus of claim 1, wherein at least the first temperature sensor and the first temperature modification device are configured to be rotatable about a vertical axis.

### Claim 5 (depends on 1)

The thermal diagnosis and treatment apparatus of claim 1, wherein at least the first temperature sensor and the first temperature modification device are configured to be movable vertically with respect to a support base.

### Claim 6 (depends on 1)

The thermal diagnosis and treatment apparatus of claim 1, wherein the first temperature sensor and the first temperature modification device are configured to be rotatable about a vertical axis, and the second temperature sensor and the second temperature modification device are configured to be rotatable about the vertical axis.

### Claim 7 (depends on 1)

The thermal diagnosis and treatment apparatus of claim 1, wherein the first temperature sensor and the first temperature modification device are configured to be movable vertically with respect to a support base, and the second temperature sensor and the second temperature modification device are configured to be separately movable vertically with respect to the support base.

### Claim 8 (depends on 1)

The thermal diagnosis and treatment apparatus of claim 1, wherein the output device is one or more of a cell phone, a watch, a television, a laptop, a display, and a tablet.

### Claim 9 (depends on 1)

The thermal diagnosis and treatment apparatus of claim 1, wherein the first temperature sensor, the first temperature modification device, the second temperature sensor, and the second temperature modification device are commonly supported on a wearable support.

### Claim 10 (depends on 9)

The thermal diagnosis and treatment apparatus of claim 9, wherein the wearable support is one of a nose clip, a hat, a cap, a headband, a head appliance, and a support frame.

### Claim 11 (depends on 9)

The thermal diagnosis and treatment apparatus of claim 9, wherein the processor is positioned on the wearable support.

### Claim 12 (depends on 1)

The thermal diagnosis and treatment apparatus of claim 1, wherein the first temperature sensor and the first temperature modification device are movably positioned on a first post.

### Claim 13 (depends on 12)

The thermal diagnosis and treatment apparatus of claim 12, wherein the first temperature sensor and the first temperature modification device are rotationally movable about the first post and movable along the first post.

### Claim 14 (depends on 12)

The thermal diagnosis and treatment apparatus of claim 12, wherein the first post is supported on a base.

### Claim 15 (depends on 12)

The thermal diagnosis and treatment apparatus of claim 12, wherein the second temperature sensor and the second temperature modification device are movably positioned on a second post.

### Claim 16 (depends on 15)

The thermal diagnosis and treatment apparatus of claim 15, wherein the second temperature sensor and the second temperature modification device are rotationally movable about the second post and movable along the second post.

### Claim 17 (depends on 15)

The thermal diagnosis and treatment apparatus of claim 15, wherein the first post and the second post are supported on a base.

### Claim 18 (depends on 17)

The thermal diagnosis and treatment apparatus of claim 17, wherein the base is mounted on a one of a floor, a table, a bed, or a rack.

### Claim 19 (depends on 12)

The thermal diagnosis and treatment apparatus of claim 12, wherein the first temperature modification device terminates in a first interface surface that is oriented at an angle that matches an angle of the first ABTT terminus when the subject is in an upright position.

### Claim 20 (depends on 19)

The thermal diagnosis and treatment apparatus of claim 19, wherein the second temperature modification device terminates in a second interface surface that is oriented at an angle that matches an angle of the second ABTT terminus when the subject is in the upright position.