# US 11,998,223 B2 · Clot retrieval device for removing a clot from a blood vessel

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- Number: US 11,998,223 B2
- Document ID: US11998223B2
- Status: Granted
- Kind: B2
- Application number: 17/207,011
- Filed: 2021-03-19
- Published: 2021-08-26
- Granted: 2024-06-04
- Earliest claimed: 2011-03-09
- Assignees: Neuravi Limited
- Applicants: Neuravi Limited
- Inventors: Eamon Brady; Michael Gilvarry; Mahmood K. Razavi; David Vale; Patrick Griffin; Brendan Casey; Jason McNamara
- Web page: https://patentgrep.com/patent/US11998223B2

## CPC

- A61B 17/221: Gripping devices in the form of loops or baskets {for gripping calculi or similar types of obstructions (surgical snare instruments A61B17/32056)}
- A61B 17/00234: {for minimally invasive surgery (A61B17/0218, A61B17/0469, A61B17/12013, A61B17/1285, A61B17/29, A61B17/320016 take precedence)}
- A61B 17/22031: {Gripping instruments, e.g. forceps, for removing or smashing calculi (A61B17/221 takes precedence)}
- A61B 17/320725: {with radially expandable cutting or abrading elements (A61B17/32075 takes precedence)}
- A61B 90/39: {Markers, e.g. radio-opaque or breast lesions markers}
- A61F 2/013: {Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting}
- A61B 2017/00238: {Type of minimally invasive operation (A61B2017/00805 takes precedence)}
- A61B 2017/00292: {mounted on or guided by flexible, e.g. catheter-like, means}
- A61B 2017/00477: {Coupling (A61B2017/0046 takes precedence)}
- A61B 2017/00526: {Methods of manufacturing}
- A61B 2017/00831: {Material properties}
- A61B 2017/00867: {shape memory effect}
- A61B 2017/22034: {for gripping the obstruction or the tissue part from inside}
- A61B 2017/22094: {for crossing total occlusions, i.e. piercing}
- A61B 2017/2212: {having a closed distal end, e.g. a loop}
- A61B 2017/2215: {having an open distal end}
- A61B 2090/3966: {Radiopaque markers visible in an X-ray image}
- A61F 2/011: {Instruments for their placement or removal}
- A61F 2002/016: {made from wire-like elements}
- A61F 2002/018: {made from tubes or sheets of material, e.g. by etching or laser-cutting}
- A61F 2230/0069: cylindrical
- A61F 2230/008: paraboloidal
- A61F 2230/0091: helically-coiled or spirally-coiled, i.e. having a 2-D spiral cross-section
- A61F 2230/0093: Umbrella-shaped, e.g. mushroom-shaped
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C)

## Abstract

A device for removing clot from a blood vessel includes a shaft. An expandable framework of struts is fixedly coupled to a distal region of the shaft. The struts can be radially expandable from a first to a second radially expanded state in a deployed configuration. An actuation cable can be connected to a plurality of connections of the engaging framework of struts to apply an expansion force, by the struts, as the struts are actuated by the actuation cable from the first radially expanded state to the second radially expanded state. In the first radially expanded state, a distal end of the struts is spaced a first axial distance away from the shaft, and wherein in the second radially expanded state, a distal end of the struts is spaced a second axial distance, different than the first axial distance, away from the shaft.

## Claims

### Claim 1

A device for removing a clot from a blood vessel, comprising:
a flexible activation cable comprising:
a shaft; and
an expandable framework of struts located distal of the shaft, the expandable framework of struts being radially expandable from a first radially expanded state to a second radially expanded state in a deployed configuration, the expandable framework of struts fixedly coupled to a stop located in a distal region of the flexible activation cable and within the expandable framework of struts,
wherein the flexible activation cable applies an expansion force, by the stop, such that the expandable framework of struts is actuated by the flexible activation cable and the stop from the first radially expanded state to the second radially expanded state;
wherein in the first radially expanded state, a distal end of the expandable framework of struts is spaced a first axial distance away from the shaft, and wherein in the second radially expanded state, the distal end of the expandable framework of struts is spaced a second axial distance, different than the first axial distance, away from the shaft.

### Claim 2 (depends on 1)

The device of claim 1, wherein the second axial distance is shorter than the first axial distance.

### Claim 3 (depends on 1)

The device of claim 1, wherein the expandable framework of struts is cylindrical and tubular.

### Claim 4 (depends on 1)

The device of claim 1, wherein a length of the expandable framework of struts in the first radially expanded state is longer than the length of the expandable framework of struts in the second radially expanded state.

### Claim 5 (depends on 1)

The device of claim 1, wherein a diameter of the expandable framework of struts in the first radially expanded state is smaller than the diameter of the expandable framework of struts in the second radially expanded state.

### Claim 6 (depends on 1)

The device of claim 1, wherein a proximal end of the shaft comprises a handle mounted over its outer diameter.

### Claim 7 (depends on 1)

The device of claim 1, wherein the expandable framework of struts comprises a closed-cell strut structure.

### Claim 8

A device for removing clot from a blood vessel, comprising:
a flexible activation cable comprising:
a proximal end;
a distal end comprising a flexible distal tip;
a shaft; and
an expandable framework of struts located distal of the shaft, the expandable framework of struts being radially expandable from a first radially expanded state to a second radially expanded state in a deployed configuration, the expandable framework of struts fixedly coupled to a distal collar proximate the distal end of the flexible activation cable, the distal collar located within the expandable framework of struts;
wherein the flexible distal tip extends distal of a distal end of the expandable framework of struts; and
wherein the flexible activation cable applies an expansion force, by the distal collar, such that the expandable framework of struts is actuated by the flexible activation cable from the first radially expanded state to the second radially expanded state;
wherein in the first radially expanded state, a distal end of the expandable framework of struts is spaced a first axial distance away from the shaft, and wherein in the second radially expanded state, the distal end of the expandable framework of struts is spaced a second axial distance, different than the first axial distance, away from the shaft.

### Claim 9 (depends on 8)

The device of claim 8, wherein the second axial distance is shorter than the first axial distance.

### Claim 10 (depends on 8)

The device of claim 8, wherein the expandable framework of struts is cylindrical and tubular.

### Claim 11 (depends on 8)

The device of claim 8, wherein a length of the expandable framework of struts in the first radially expanded state is longer than the length of the expandable framework of struts in the second radially expanded state.

### Claim 12 (depends on 8)

The device of claim 8, wherein a diameter of the expandable framework of struts in the first radially expanded state is smaller than the diameter of the expandable framework of struts in the second radially expanded state.

### Claim 13 (depends on 8)

The device of claim 8, wherein a proximal end of the shaft comprises a handle mounted over its outer diameter.

### Claim 14 (depends on 8)

The device of claim 8, wherein the expandable framework of struts comprises a closed-cell strut structure.

### Claim 15 (depends on 8)

The device of claim 8, wherein, as the actuation cable actuates the expandable framework of struts, from a handle positioned at the proximal end of the shaft, the expandable framework of struts radially expands and a length of the expandable framework of struts shortens.
