# US 11,994,665 B2 · Systems and methods for processing electronic images of pathology data and reviewing the pathology data > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,994,665 B2 - Document ID: US11994665B2 - Status: Granted - Kind: B2 - Application number: 17/815,034 - Filed: 2022-07-26 - Published: 2023-02-02 - Granted: 2024-05-28 - Earliest claimed: 2021-07-28 - Assignees: Paige.AI, Inc. - Applicants: PAIGE.AI, Inc. - Inventors: Sam Seymour; Todd Parker; Alican Bozkurt; Christopher Kanan; Jeremy Daniel Kunz - Web page: https://patentgrep.com/patent/US11994665B2 ## CPC - G02B 21/365: {Control or image processing arrangements for digital or video microscopes (G02B21/361, G02B21/362 take precedence)} - G02B 21/368: {details of associated display arrangements, e.g. mounting of LCD monitor} - G06T 7/70: Determining position or orientation of objects or cameras (camera calibration G06T7/80) - G02B: OPTICAL ELEMENTS, SYSTEMS OR APPARATUS - G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL ## Abstract A computer-implemented method of reviewing digital pathology data may include receiving a digital pathology image into a digital storage device, the digital pathology image being associated with a patient, providing for display the digital pathology image on a display, pairing the digital pathology image with a physical token of the digital pathology image in an interactive system, receiving one or more commands from the interactive system, determining one or more manipulations or modifications to the displayed digital pathology image based on the one or more commands, and providing for display a modified digital pathology image on the display according to the determined one or more manipulations or modifications. ## Claims ### Claim 1 A computer-implemented method of reviewing digital pathology data, the method comprising: receiving a digital pathology image into a digital storage device, the digital pathology image being associated with a patient; providing for display the digital pathology image on a display; pairing the digital pathology image with a physical token of the digital pathology image in an interactive system, the system including a control to select a visualization of the digital pathology image; receiving one or more commands from the interactive system indicating a selected visualization of the digital pathology image; determining one or more manipulations or modifications to the displayed digital pathology image based on the selected visualization; and providing for display a modified digital pathology image on the display according to the determined one or more manipulations or modifications. ### Claim 2 (depends on 1) The computer-implemented method of claim 1, the method further comprising: receiving information of a position or an orientation of the physical token from one or more sensors included in the physical token. ### Claim 3 (depends on 1) The computer-implemented method of claim 1, the method further comprising: receiving information of a position or an orientation of the physical token from one or more sensors included in a surface configured to support the physical token. ### Claim 4 (depends on 3) The computer-implemented method of claim 3, wherein the interactive system further includes a mock microscope, the mock microscope including a stage, and the surface being incorporated in the stage of the mock microscope. ### Claim 5 (depends on 3) The computer-implemented method of claim 3, wherein the selected visualization is one of a tissue map visualization, a tissue hop visualization, or a point of focus visualization. ### Claim 6 (depends on 1) The computer-implemented method of claim 1, wherein the one or more commands further include a change in a position or an orientation of the physical token. ### Claim 7 (depends on 6) The computer-implemented method of claim 6, wherein the one or more commands further include instructions to rotate the digital pathology image or adjust a zoom level of the digital pathology image according to the change in the position or the orientation of the physical token. ### Claim 8 (depends on 6) The computer-implemented method of claim 6, wherein the one or more commands further include navigation of the digital pathology image according to the change in the position or the orientation of the physical token. ### Claim 9 (depends on 6) The computer-implemented method of claim 6, wherein providing for display the modified digital pathology image on the display includes providing for display a movement of the digital pathology image that corresponds to a movement of the physical token indicated by the change in the position or the orientation of the physical token. ### Claim 10 (depends on 1) The computer-implemented method of claim 1, wherein receiving the digital pathology image includes receiving a plurality of digital pathology images, the digital image displayed is selected from the plurality of digital pathology images, and the one or more commands includes instructions to advance to another digital pathology image of the plurality of digital pathology images. ### Claim 11 A system for reviewing digital pathology data, the system comprising: a data storage device storing instructions for reviewing digital pathology data in an electronic storage medium; and a processor configured to execute the instructions to perform operations comprising: receiving a digital pathology image into a digital storage device, the digital pathology image being associated with a patient; providing for display the digital pathology image on a display; pairing the digital pathology image with a physical token of the digital pathology image in an interactive system, the system including a control to select a visualization of the digital pathology image; receiving one or more commands from the interactive system indicating a selected visualization of the digital pathology image; determining one or more manipulations or modifications to the displayed digital pathology image based on the selected visualization; and providing for display a modified digital pathology image on the display according to the determined one or more manipulations or modifications. ### Claim 12 (depends on 11) The system of claim 11, wherein the operations further comprise: receiving information of a position or an orientation of the physical token from one or more sensors included in the physical token or from one or more sensors included in a surface configured to support the physical token. ### Claim 13 (depends on 11) The system of claim 11, wherein the selected visualization is one of a tissue map visualization, a tissue hop visualization, or a point of focus visualization. ### Claim 14 (depends on 11) The system of claim 11, wherein the one or more commands further include a change in a position or an orientation of the physical token. ### Claim 15 (depends on 14) The system of claim 14, wherein providing for display the modified digital pathology image on the display includes providing for display a movement of the digital pathology image that corresponds to a movement of the physical token indicated by the change in the position or the orientation of the physical token. ### Claim 16 A non-transitory machine-readable medium storing instructions that, when executed by a computing system, causes the computing system to perform operations for reviewing digital pathology data, the operations comprising: receiving a digital pathology image into a digital storage device, the digital pathology image being associated with a patient; providing for display the digital pathology image on a display; pairing the digital pathology image with a physical token of the digital pathology image in an interactive system, the system including a control to select a visualization of the digital pathology image; receiving one or more commands from the interactive system indicating a selected visualization of the digital pathology image; determining one or more manipulations or modifications to the displayed digital pathology image based on the selected visualization; and providing for display a modified digital pathology image on the display according to the determined one or more manipulations or modifications. ### Claim 17 (depends on 16) The non-transitory machine-readable medium of claim 16, the operations further comprising: receiving information of a position or an orientation of the physical token from one or more sensors included in the physical token or from one or more sensors included in a surface configured to support the physical token. ### Claim 18 (depends on 16) The non-transitory machine-readable medium of claim 16, wherein the selected visualization is one of a tissue map visualization, a tissue hop visualization, or a point of focus visualization. ### Claim 19 (depends on 16) The non-transitory machine-readable medium of claim 16, wherein the one or more commands further include a change in a position or an orientation of the physical token. ### Claim 20 (depends on 19) The non-transitory machine-readable medium of claim 19, wherein displaying the modified digital pathology image on the display includes displaying a movement of the digital pathology image that corresponds to a movement of the physical token indicated by the change in the position or the orientation of the physical token.