Techniques for temperature control of separation devices and optical detection devices of mass analysis systems
AssigneeWaters Technologies Corporation
InventorsMark J. Basile, Jeffrey Musacchio, Michael O. Fogwill, Sebastien Besner, Joseph D. Michienzi, Wade P. Leveille
Life of this patent
Estimating the term…
Abstract
Techniques and apparatus for thermally controlled interfaces for separation devices and optical flow cell devices with minimized post-column volumes are described. In one embodiment, for example, a column-optical cell assembly may include an insulating device, a chromatography column arranged within the insulating device, and an optical flow cell in fluid communication with the chromatography column, the chromatography column arranged within a minimum distance of the optical flow cell.
Claims14
A column-optical cell assembly, comprising:
- a column thermal insulation sleeve;
- a mobile phase preheater arranged within the column thermal insulation sleeve for preheating mobile phase;
- a liquid chromatography column arranged within the column thermal insulation sleeve;
- an optical cell thermal insulation sleeve;
- and
- an optical flow cell arranged in the optical cell thermal insulation sleeve and in fluid communication with the liquid chromatography column, the liquid chromatography column arranged within 30 millimeters of the optical flow cell.
Dependencies are inferred from the claim text.