Method for producing peptide compound
AssigneesNissan Chemical Corporation, PeptiDream Inc.
InventorsMichiharu Handa, Naohiko Yasuda, Akihiro Nagaya, Hiroyuki Kousaka
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AssigneesNissan Chemical Corporation, PeptiDream Inc.
InventorsMichiharu Handa, Naohiko Yasuda, Akihiro Nagaya, Hiroyuki Kousaka
Estimating the term…
The invention provides a method for producing a peptide which comprises the following steps (1) and (2): (1) a step of condensing a C-protected amino acid or a C-protected peptide to a C-terminal of an N-protected amino acid or an N-protected peptide represented by the formula (I): wherein Y represents an amino acid in which a C-terminal is unprotected or a peptide in which a C-terminal is unprotected, R1, R2 and R3 each independently represent an aliphatic hydrocarbon group which may have a substituent(s), a total number of the carbon atoms in the R1R2R3Si group is 10 or more, and the R1R2R3SiOC(O) group is bonded to the N-terminal in Y, and (2) a step of removing the protective group at the C-terminal of the peptide obtained in step (1).
A method for producing a peptide, which comprises the following Steps (1) and (2):
Dependencies are inferred from the claim text.