# US 11,992,708 B2 · Nitinol organ positioner to prevent damage to healthy tissue during radiation oncology treatments

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- Number: US 11,992,708 B2
- Document ID: US11992708B2
- Status: Granted
- Kind: B2
- Application number: 16/585,962
- Filed: 2019-09-27
- Published: 2020-01-16
- Granted: 2024-05-28
- Earliest claimed: 2016-06-22
- Assignees: The University of Toledo
- Applicants: The University of Toledo
- Inventors: E. Ishmael Parsai; Mohammad Elahinia
- Web page: https://patentgrep.com/patent/US11992708B2

## CPC

- A61N 5/1069: {Target adjustment, e.g. moving the patient support}
- A61N 5/1049: {for verifying the position of the patient with respect to the radiation beam}
- A61N 5/1077: {Beam delivery systems}
- A61N 2005/1094: {Shielding, protecting against radiation}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)

## Abstract

Devices, systems, and methods for repositioning organs, such as the rectum, during radiation therapy treatments, are described.

## Claims

### Claim 1

A method of repositioning an organ, the method comprising:
inserting an organ repositioner device into an anatomical location, wherein the organ repositioner device comprises an assembly of a shape memory (SM) element and a superelastic (SE) element, the SM element comprising a first shape memory alloy and the SE element comprising a second shape memory alloy, wherein at a first temperature the first shape memory alloy is in a martensite phase while the second shape memory alloy is in an austenite phase; and
actuating the assembly to cause the organ repositioner device to reposition the organ near the anatomical location.

### Claim 2 (depends on 1)

The method of claim 1, wherein the actuation is caused by cooling the assembly.

### Claim 3 (depends on 1)

The method of claim 1, wherein the actuation is caused by heating the assembly.

### Claim 4 (depends on 1)

The method of claim 1, further comprising monitoring the actuation of the assembly by measuring electrical resistance in the assembly.

### Claim 5 (depends on 1)

The method of claim 1, wherein the actuation is controlled using an artificial neural network.

### Claim 6 (depends on 1)

The method of claim 1, further comprising administering a radiation therapy to a prostate nearby the anatomical location.

### Claim 7

A method of repositioning an organ for a radiation treatment, the method comprising:
positioning an organ repositioner device in a first configuration in an anatomical location, the organ repositioner device comprising an assembly of a shape memory (SM) element and a superelastic (SE) element, the SM element comprising a first shape memory alloy and the SE element comprising a second shape memory alloy, wherein the SM element is a round wire and the SE element is a flat wire, and wherein either the round wire is wrapped around the flat wire or the flat wire is wrapped around the round wire;
cooling or heating the organ repositioner device to deform the organ repositioner device into a second configuration, wherein deformation into the second configuration causes the organ repositioner device to reposition the organ at or near the atomical location, wherein in one of the first configuration or the second configuration the first shape memory alloy is in a martensite phase while the second shape memory alloy is in an austenite phase; and
sensorlessly monitoring the deformation of the organ repositioner device by measuring electrical resistance in the organ repositioner device.

### Claim 8 (depends on 7)

The method of claim 7, further comprising administering a radiation therapy to or nearby the anatomical location.

### Claim 9

A method of repositioning an organ, the method comprising:
inserting an organ repositioner device into a rectum, wherein the organ repositioner device comprises an assembly of a shape memory (SM) element and a superelastic (SE) element, the SM element and SE element comprising shape memory alloys, wherein the SM element is wrapped around the SE element or the SE element is wrapped around the SM element; and
actuating the assembly to cause the organ repositioner device to reposition the rectum away from a prostate by pushing a posterior rectum wall; and
administering a radiation therapy to or nearby the prostate.

### Claim 10 (depends on 9)

The method of claim 9, wherein the actuation is caused by cooling the assembly.

### Claim 11 (depends on 9)

The method of claim 9, wherein the actuation is caused by heating the assembly.

### Claim 12 (depends on 9)

The method of claim 9, further comprising monitoring the actuation of the assembly by measuring electrical resistance in the assembly.

### Claim 13 (depends on 9)

The method of claim 9, wherein the actuation is controlled using an artificial neural network.