# US 11,992,707 B2 · 3D imaging with simultaneous treatment and non-treatment imaging beams

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- Number: US 11,992,707 B2
- Document ID: US11992707B2
- Status: Granted
- Kind: B2
- Application number: 18/133,464
- Filed: 2023-04-11
- Published: 2023-08-10
- Granted: 2024-05-28
- Earliest claimed: 2021-06-30
- Assignees: Accuray Incorporated
- Applicants: Accuray Incorporated
- Inventors: Eric Schnarr; Calvin R. Maurer; Rich Holloway; Jacob D. Shea; Charles Brandon Frederick
- Web page: https://patentgrep.com/patent/US11992707B2

## CPC

- A61N 5/1049: {for verifying the position of the patient with respect to the radiation beam}
- A61N 5/1067: {in real time, i.e. during treatment}
- A61N 5/1031: {using a specific method of dose optimization}
- A61N 5/1038: {taking into account previously administered plans applied to the same patient, i.e. adaptive radiotherapy}
- A61N 5/1045: {using a multi-leaf collimator, e.g. for intensity modulated radiation therapy or IMRT}
- A61N 5/1071: {for verifying the dose delivered by the treatment plan}
- A61N 5/1078: {Fixed beam systems}
- A61N 2005/1054: {using a portal imaging system}
- A61N 2005/1061: {using an x-ray imaging system having a separate imaging source}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)

## Abstract

A radiation treatment session is initiated to deliver a therapeutic radiation beam from a therapeutic radiation source to a target. One or more X-ray radiation sources are caused to deliver an imaging radiation beam from the one or more X-ray radiation sources through the target to one or more X-ray detectors to acquire imaging data associated with the target during therapeutic radiation beam delivery. One or more volumetric images are constructed using the acquired imaging data.

## Claims

### Claim 1

An X-ray imaging and radiation delivery system, comprising:
a therapeutic X-ray source to create a therapeutic X-ray beam;
one or more X-ray imaging sources to create one or more imaging X-ray beams, wherein the one or more X-ray imaging sources and the therapeutic X-ray source are positioned to simultaneously direct the therapeutic X-ray beam and the one or more imaging X-ray beams to a target; and
a processing device, operatively coupled to the therapeutic X-ray source and the one or more X-ray imaging sources, to:
turn on the therapeutic X-ray beam to initiate a radiation treatment session and deliver the therapeutic X-ray beam from the therapeutic X-ray source to theft target as the therapeutic X-ray source travels about the target;
turn off the therapeutic X-ray beam to end the radiation treatment session;
acquire, during the radiation treatment session, imaging data associated with the target by causing the one or more X-ray imaging sources to deliver the one or more imaging X-ray beams through the target to one or more X-ray detectors; and
construct one or more volumetric images using the imaging data.

### Claim 2 (depends on 1)

The radiation delivery system of claim 1, wherein delivery of the one or more imaging X-ray beams is after turning on the therapeutic X-ray beam and before turning off the therapeutic X-ray beam.

### Claim 3 (depends on 1)

The radiation delivery system of claim 1, wherein delivery of the one or more imaging X-ray beams is concurrent with delivery of the therapeutic X-ray beam.

### Claim 4 (depends on 3)

The radiation delivery system of claim 3, wherein the processing device further causes the therapeutic X-ray source to deliver the one or more imaging X-ray beams within a same interval as delivery of the therapeutic X-ray beam.

### Claim 5 (depends on 1)

The radiation delivery system of claim 1, wherein delivery of the one or more imaging X-ray beams is interleaved with delivery of the therapeutic X-ray beam.

### Claim 6 (depends on 5)

The radiation delivery system of claim 5, wherein the therapeutic X-ray beam is active between one or more pulses of the one or more imaging X-ray beams, and wherein construction of the one or more volumetric images is based on the imaging data acquired from the one or more pulses of the one or more imaging X-ray beams.

### Claim 7 (depends on 1)

The radiation delivery system of claim 1, wherein the therapeutic X-ray source includes a LINAC X-ray source, and wherein the processing device is further to acquire, during the radiation treatment session, imaging data associated with the target by causing the LINAC X-ray source to deliver a MV imaging beam of the one or more imaging X-ray beams through the target to the one or more X-ray detectors.

### Claim 8 (depends on 1)

The radiation delivery system of claim 1, wherein the one or more X-ray detectors are tunable to selectively detect the one or more imaging X-ray beams.

### Claim 9 (depends on 1)

The radiation delivery system of claim 1, wherein the one or more volumetric images are constructed using less than a completely sampled set of imaging data.

### Claim 10 (depends on 1)

The radiation delivery system of claim 1, wherein the processing device is further to cause a multi-leaf collimator to form an opening that comprises a union of a first opening to shape the therapeutic X-ray beam to correspond to the target and a second opening to shape the one or more imaging X-ray beams into a fan beam to acquire the imaging data.

### Claim 11 (depends on 1)

The radiation delivery system of claim 1, wherein the processing device is further to estimate a therapeutic dose delivered to one or more of the target or an object in proximity to the target based on the one or more volumetric images.

### Claim 12 (depends on 1)

The radiation delivery system of claim 1, wherein the processing device is further to modify therapeutic radiation delivery for the radiation treatment session based on the one or more volumetric images.

### Claim 13

A method comprising:
turning on, by a processing device of an X-ray imaging and radiation delivery system, a therapeutic X-ray beam to initiate a radiation treatment session and deliver the therapeutic X-ray beam from a therapeutic X-ray source to a target as the therapeutic X-ray source travels about the target;
turning off, by the processing device, the therapeutic X-ray beam to end the radiation treatment session;
acquiring, by the processing device during the radiation treatment session, imaging data associated with the target by causing one or more X-ray imaging sources to deliver one or more imaging X-ray beams through the target to one or more X-ray detectors, wherein the one or more X-ray imaging sources and the therapeutic X-ray source are positioned to simultaneously direct the therapeutic X-ray beam and the one or more imaging X-ray beams to the target; and
constructing, by the processing device, one or more volumetric images using the imaging data.

### Claim 14 (depends on 13)

The method of claim 13, wherein delivery of the one or more imaging X-ray beams is after turning on the therapeutic X-ray beam and before turning off the therapeutic X-ray beam.

### Claim 15 (depends on 13)

The method of claim 13, wherein delivery of the one or more imaging X-ray beams is concurrent with delivery of the therapeutic X-ray beam.

### Claim 16 (depends on 13)

The method of claim 13, wherein delivery of the one or more imaging X-ray beams is interleaved with delivery of the therapeutic X-ray beam.

### Claim 17

A non-transitory computer-readable storage medium including instructions which, when executed by a processing device of an X-ray imaging and therapy system, cause the processing device to:
turn on a therapeutic X-ray beam to initiate a radiation treatment session and deliver the therapeutic X-ray beam from a therapeutic X-ray source to a target as the therapeutic X-ray source travels about the target;
turn off the therapeutic X-ray beam to end the radiation treatment session;
acquire, during the radiation treatment session, imaging data associated with the target by causing one or more X-ray imaging sources to deliver one or more imaging X-ray beams through the target to one or more X-ray detectors, wherein the one or more X-ray imaging sources and the therapeutic X-ray source are positioned to simultaneously direct the therapeutic X-ray beam and the one or more imaging X-ray beams to the target; and
construct one or more volumetric images using the imaging data.

### Claim 18 (depends on 17)

The non-transitory computer-readable storage medium of claim 17, wherein delivery of the one or more imaging X-ray beams is after turning on the therapeutic X-ray beam and before turning off the therapeutic X-ray beam.

### Claim 19 (depends on 17)

The non-transitory computer-readable storage medium of claim 17, wherein delivery of the one or more imaging X-ray beams is concurrent with delivery of the therapeutic X-ray beam.

### Claim 20 (depends on 17)

The non-transitory computer-readable storage medium of claim 17, wherein delivery of the one or more imaging X-ray beams is interleaved with delivery of the therapeutic X-ray beam.
