# US 11,992,706 B2 · Simulation phantom

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- Number: US 11,992,706 B2
- Document ID: US11992706B2
- Status: Granted
- Kind: B2
- Application number: 17/624,515
- Filed: 2020-06-30
- Published: 2022-11-17
- Granted: 2024-05-28
- Earliest claimed: 2019-07-02
- Assignees: Our United Corporation
- Applicants: Our United Corporation
- Inventors: Zhongya Wang; Hao Yan; Jiuliang Li
- Web page: https://patentgrep.com/patent/US11992706B2

## CPC

- A61N 5/1039: {using functional images, e.g. PET or MRI}
- A61N 5/1075: {for testing, calibrating, or quality assurance of the radiation treatment apparatus}
- A61B 5/0035: {adapted for acquisition of images from more than one imaging mode, e.g. combining MRI and optical tomography}
- A61B 6/583: {using calibration phantoms}
- A61B 8/587: {Calibration phantoms}
- G01R 33/4812: {MR combined with X-ray or computed tomography [CT]}
- G01R 33/58: Calibration of imaging systems, e.g. using test probes {, Phantoms; Calibration objects or fiducial markers such as active or passive RF coils surrounding an MR active material}
- A61B 5/0036: {including treatment, e.g., using an implantable medical device, ablating, ventilating}
- A61B 5/055: involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
- A61B 6/032: {Transmission computed tomography [CT]}
- A61B 6/4085: {Cone-beams}
- A61B 6/4417: {related to combined acquisition of different diagnostic modalities}
- A61B 6/5247: {combining images from an ionising-radiation diagnostic technique and a non-ionising radiation diagnostic technique, e.g. X-ray and ultrasound}
- A61N 2005/1076: {using a dummy object placed in the radiation field, e.g. phantom}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G01R: MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES (indicating correct tuning of resonant circuits H03J3/12)

## Abstract

Provided is a simulation phantom including a simulated target volume and a simulated normal tissue encasing the simulated target volume, wherein the simulated target volume and a portion of the simulated normal tissue abutting the simulated target volume have a first characteristic to enable the simulation phantom to be imaged on a first imaging device, and the simulated target volume and the portion of the simulated normal tissue abutting the simulated target volume further have a second characteristic to enable the simulation phantom to be imaged on a second imaging device different from the first imaging device.

## Claims

### Claim 1

A simulation phantom, comprising:
a simulated target volume; and
a simulated normal tissue encasing the simulated target volume, wherein the simulated target volume and a portion of the simulated normal tissue abutting the simulated target volume have a first characteristic to enable the simulation phantom to be imaged on a first imaging device, and the simulated target volume and the portion of the simulated normal tissue abutting the simulated target volume further have a second characteristic to enable the simulation phantom to be imaged on a second imaging device different from the first imaging device.

### Claim 2 (depends on 1)

The simulation phantom according to claim 1, wherein the first characteristic indicates a difference in CT value and the first imaging device is a CT imaging device; and the second characteristic indicates a difference in hydrogen-containing density and the second imaging device is a magnetic resonance imaging device.

### Claim 3 (depends on 1)

The simulation phantom according to claim 1, further comprising a cassette for accommodating the simulated target volume, wherein a cassette recess is provided in the simulated normal tissue at a position corresponding to the cassette, the cassette is capable of being housed in the cassette recess, and is detachably connected with the cassette recess, and the simulated target volume and the cassette have the first characteristic and the second characteristic.

### Claim 4 (depends on 3)

The simulation phantom according to claim 3, wherein the simulated normal tissue comprises a first body and a second body that are detachably connected to each other, and the cassette is capable of being housed in or removed from the cassette recess by detaching the first body and the second body.

### Claim 5 (depends on 3)

The simulation phantom according to claim 3, wherein a film housing groove for housing a film is provided within the cassette.

### Claim 6 (depends on 5)

The simulation phantom according to claim 5, wherein the cassette comprises a first cassette and a second cassette opposite to the first cassette and detachably connected to each other, and the film housing groove is formed between opposite surfaces of the first cassette and the second cassette.

### Claim 7 (depends on 6)

The simulation phantom according to claim 6, wherein the first cassette and the second cassette are detachably connected to each other via a locating pin and locating hole that are mutually fitted.

### Claim 8 (depends on 3)

The simulation phantom according to claim 3, wherein in a case that the simulation phantom is a simulated head phantom, the cassette is disposed between a back surface and a front surface of the simulated head phantom.

### Claim 9 (depends on 3)

The simulation phantom according to claim 3, wherein the cassette is in a cuboid or cube shape.

### Claim 10 (depends on 1)

The simulation phantom according to claim 1, wherein the simulated target volume is in a sphere shape.

### Claim 11 (depends on 1)

The simulation phantom according to claim 1, wherein a plurality of precisely-marked points for positioning the simulation phantom are provided at an outer surface of the simulated normal tissue.

### Claim 12 (depends on 11)

The simulation phantom according to claim 11, wherein in a case that the simulation phantom is a simulated head phantom, the plurality of precisely-marked points comprise a first precisely-marked point, a second precisely-marked point and a third precisely-marked point, wherein the first precisely-marked point is disposed at a forehead of the simulated head phantom; the second precisely-marked point and the third precisely-marked point are respectively disposed at opposite positions of two sides of the forehead of the simulated head phantom; and a center point of the simulated target volume coincides with an intersection between a connecting line connecting the second precisely-marked point and the third precisely-marked point, and a line perpendicular to the connecting line and passing through the first precisely-marked point.

### Claim 13 (depends on 11)

The simulation phantom according to claim 11, wherein the precisely-marked points and the outer surface of the simulated normal tissue at least have the first characteristic or the second characteristic.

### Claim 14 (depends on 1)

The simulation phantom according to claim 1, wherein a plurality of marked points are provided inside the simulated normal tissue, and the plurality of marked points and portions of the simulated normal tissue abutting the marked points at least have the first characteristic or the second characteristic.

### Claim 15 (depends on 14)

The simulation phantom according to claim 14, wherein in a case that the simulation phantom is a simulated head phantom, the plurality of marked points are disposed in a simulated soft tissue of a forehead of the simulated head phantom.

### Claim 16 (depends on 1)

The simulation phantom according to claim 1, wherein a spherical hollow cavity is provided in a center of the simulated target volume, and a spherical point of the spherical hollow cavity coincides with a center point of the simulated target volume.

### Claim 17 (depends on 1)

The simulation phantom according to claim 1, wherein the simulation phantom is a simulated head phantom, a simulated head-neck phantom or a simulated body phantom.

### Claim 18 (depends on 17)

The simulation phantom according to claim 17, wherein in a case that the simulation phantom is the simulated head phantom or the simulated head-neck phantom, the simulated normal tissue comprises a simulated skull, a simulated soft tissue filled within the simulated skull, and a simulated skin disposed outside the simulated skull, and wherein the simulated target volume is disposed within the simulated soft tissue, and the simulated skull, the simulated soft tissue, and the simulated skin at least have the first characteristic or the second characteristic.

### Claim 19 (depends on 1)

The simulation phantom according to claim 1, further comprising: a simulated target volume driving device for driving the simulated target volume to move along a predetermined trajectory at a predetermined frequency.