# US 11,992,688 B2 · Intracardiac energy harvesting device and implantable electronic medical device > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,992,688 B2 - Document ID: US11992688B2 - Status: Granted - Kind: B2 - Application number: 17/917,925 - Filed: 2020-05-26 - Published: 2023-05-18 - Granted: 2024-05-28 - Earliest claimed: 2020-04-09 - Assignees: Wei Hua; Zhou Li - Applicants: Wei Hua; Zhou Li - Inventors: Zhou Li; Wei Hua; Zhuo Liu; Yiran Hu; Han Ouyang - Web page: https://patentgrep.com/patent/US11992688B2 ## CPC - A61N 1/37: Monitoring; Protecting - A61N 1/3756: {Casings with electrodes thereon, e.g. leadless stimulators} - A61N 1/37205: {Microstimulators, e.g. implantable through a cannula} - A61N 1/375: Constructional arrangements, e.g. casings - A61N 1/3785: {generated by biological activity or substance, e.g. body movement} - H02N 2/18: producing electrical output from mechanical input, e.g. generators (for measurement devices G01) - A61N 1/362: Heart stimulators (heart defibrillators A61N1/39) - A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B) - H02N: ELECTRIC MACHINES NOT OTHERWISE PROVIDED FOR ## Abstract An intracardiac energy harvesting device includes a shell; a fixing mechanism arranged on the shell, and a fixing mechanism configured to fix the shell to an interior of a heart chamber to enable the shell to move along with beating of heart; wherein a nanogenerator module is packaged in the shell, which is configured to output electric energy in response to movement of the shell along with the heart beat; and a power management module is packaged in the shell for managing electric energy output by the nanogenerator module. According to the intracardiac energy collecting device disclosed by the present invention, the biological mechanical energy generated by heart beating can be collected in the heart through a minimally invasive interventional operation mode, surgical wounds are small, damage to the heart cannot be caused, and infection can be effectively avoided. ## Claims ### Claim 1 An intracardiac energy harvesting device, comprising: a shell; a fixing mechanism arranged on the shell, wherein the fixing mechanism is configured to fix the shell to an interior of a heart chamber to enable the shell to move along with beating of heart; a nanogenerator module packaged in the shell, wherein the nanogenerator module is configured to output electrical energy in response to movement of the shell as the heart beats; and a power management module packaged in the shell, wherein the power management module is used for managing an electric energy output by the nanogenerator module; a first cavity; at least one power generation unit disposed in the first cavity; and at least one first runout body, which is freely movable in the first cavity; wherein the first runout body is configured to contact and/or impact the power generation unit in response to runout of the heart, so that the power generation unit outputs an electrical signal; the power generation unit is a triboelectric nanogenerator, which comprises: a first friction layer and a second friction layer; spaces are formed on both sides of the power generation unit, and the spaces on both sides are provided with at least one of the runout bodies; when the first runout body moves, the first friction layer is in contact with and separated from the second friction layer. ### Claim 2 (depends on 1) The intracardiac energy harvesting device, as recited in claim 1, wherein the triboelectric nanogenerator comprises: a first electrode layer, and the first friction layer disposed in contact with the first electrode layer; and a second electrode layer, and the second friction layer disposed in contact with the second electrode layer; wherein the first friction layer and the second friction layer are arranged in a face-to-face manner and are spaced apart by a space for free movement of the first runout body, the first runout body is configured to move between the first friction layer and the second friction layer in response to the runout of the heart, so that the first runout body is in contact with and separated from the first friction layer and is in contact with and separated from the second friction layer, so that the first electrode layer and the second electrode layer output electrical signals to the power management module. ### Claim 3 (depends on 1) The intracardiac energy harvesting device, as recited in claim 1, wherein there is an electron difference between a material of the first friction layer and a material of the second friction layer; each of the first friction layer and the second friction layer is selected from a group consisting of an insulator material, a semiconductor material, and a conductor material. ### Claim 4 (depends on 1) The intracardiac energy harvesting device, as recited in claim 1, wherein the first friction layer and the second friction layer is a conductor material, and a friction layer of the conductor material replaces an electrode layer disposed in contact therewith. ### Claim 5 (depends on 1) The intracardiac energy harvesting device, as recited in claim 1, wherein at least one of a contact surface of the first friction layer and a contact surface of the second friction layer is selected from a group consisting of a micro-nano structure, a dot conjugate of a nanomaterial, and a coating of a nanomaterial. ### Claim 6 (depends on 1) The intracardiac energy harvesting device, as recited in claim 1, wherein the triboelectric nanogenerator comprises a first substrate, and the first friction layer is disposed on the first substrate; when the first runout body located on one side of the first substrate moves, the first substrate is impacted, so that the first friction layer and the second friction layer are in contact and separated; and/or the triboelectric nanogenerator comprises a second substrate, and the second friction layer is arranged on the second substrate; when the first runout body on one side of the second substrate moves, the second substrate is impacted, so that the first friction layer and the second friction layer are in contact and separated. ### Claim 7 (depends on 6) The intracardiac energy harvesting device, as recited in claim 6, wherein at least one of the first substrate and the second substrate comprises a flexible material to deform due to an impact force of the first runout body and return to an initial state when the impact force of the first runout body is removed; or at least one of the first substrate and the second substrate comprises a flexible material to deform due to an external force, which has an extensibility to extend or retract. ### Claim 8 (depends on 7) The intracardiac energy harvesting device, as recited in claim 7, wherein in a natural state, the first substrate is arc-shaped or arched, and/or the second substrate is arc-shaped or arched. ### Claim 9 (depends on 1) The intracardiac energy harvesting device, as recited in claim 1, wherein the triboelectric nanogenerator comprises a first substrate, and the first friction layer is disposed on the first substrate; the first substrate is fixed on an internal wall of the first cavity; and/or the triboelectric nanogenerator comprises a second substrate, and the second friction layer is arranged on the second substrate; the second substrate is fixed on an internal wall of the first cavity. ### Claim 10 (depends on 1) The intracardiac energy harvesting device, as recited in claim 1, wherein an outer diameter of the first runout body is 100 μm-5 mm. ### Claim 11 (depends on 1) The intracardiac energy harvesting device, as recited in claim 1, wherein an outer surface of the first runout body is selected from a group consisting of a micro-nano structure, a dot conjugate of a nanomaterial, and a coating of a nanomaterial. ### Claim 12 (depends on 1) The intracardiac energy harvesting device, as recited in claim 1, wherein the first runout body is a polyhedron, a sphere or an ellipsoid. ### Claim 13 (depends on 1) The intracardiac energy harvesting device, as recited in claim 1, wherein the intracardiac energy harvesting device has a size and shape adapted to be implanted into the interior of the heart chamber by an interventional procedure. ### Claim 14 (depends on 1) The intracardiac energy harvesting device, as recited in claim 1, wherein an outer diameter of the shell is 5 mm to 15 mm, a length of the shell is 1 cm to 5 cm; a length of the nanogenerator module is 0.5 cm to 4.5 cm. ### Claim 15 (depends on 1) The intracardiac energy harvesting device, as recited in claim 1, wherein the shell is cylindrical. ### Claim 16 (depends on 1) The intracardiac energy harvesting device, as recited in claim 1, wherein the fixing mechanism is disposed at an end or a side portion of the shell. ### Claim 17 (depends on 1) The intracardiac energy harvesting device, as recited in claim 1, wherein the fixing mechanism is selected from a group consisting of a claw-shaped fixing mechanism, a hook-shaped fixing mechanism, a spiral fixing mechanism and a screw fixing mechanism. ### Claim 18 (depends on 1) An implantable electronic medical device, comprising: the intracardiac energy harvesting device as recited in claim 1; and a load function unit electrically connected with an output end of a power management module of an energy harvesting device in the heart, and the intracardiac energy harvesting device is used for providing electric energy for the load function unit. ### Claim 19 (depends on 18) The implantable electronic medical device, as recited in claim 18, wherein the load function unit is integrated with the intracardiac energy harvesting device. ### Claim 20 (depends on 18) The implantable electronic medical device, as recited in claim 18, wherein the implantable electronic medical device is a leadless cardiac pacemaker, and the load functional unit comprises: a heart rate sensing unit configured to sense a heart rate; a pulse emission unit configured to emit an electric pulse in response to the heart rate sensed by the heart rate sensing unit; and an electrode portion configured to contact heart tissue to conduct a heart rate sensing signal to a heart rate sensing portion and conduct an electrical pulse generated by a pulse emitting portion to the heart.