# US 11,992,643 B2 · Neurovascular insertion tool > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,992,643 B2 - Document ID: US11992643B2 - Status: Granted - Kind: B2 - Application number: 17/119,601 - Filed: 2020-12-11 - Published: 2021-06-24 - Granted: 2024-05-28 - Earliest claimed: 2019-12-20 - Assignees: Neuravi Limited - Applicants: Neuravi Limited - Inventors: Declan Lee; Maeve Holian - Web page: https://patentgrep.com/patent/US11992643B2 ## CPC - A61M 25/00: Catheters; Hollow probes (dilators A61M29/00; {peritoneal catheters A61M1/285; tracheal tubes A61M16/04; for drainage A61M27/00; for uterus, vagina or rectum A61M31/00} ; for measuring or testing A61B; {materials for catheters A61L29/00}) - A61M 39/0247: {Transcutaneous or percutaneous access sites to the inside of the body} - A61M 39/06: Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof - A61B 17/22: Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for - A61B 17/3423: {Access ports, e.g. toroid shape introducers for instruments or hands (access sites for liquids A61M39/0247)} - A61F 2/9522: {Means for mounting a stent or stent-graft onto or into a placement instrument} - A61M 25/104: {used for angioplasty} - A61M 2025/0042: {Microcatheters, cannula or the like having outside diameters around 1 mm or less} - A61M 2039/0258: {for vascular access, e.g. blood stream access} - A61M 2039/0626: {used with other surgical instruments, e.g. endoscope, trocar} - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) ## Abstract An improved insertion apparatus simplifies loading of neurovascular device into microcatheter. In one example, the insertion apparatus can include a tapered distal tip, allowing the insertion apparatus to reach the microcatheter with no gap. In another example, the insertion apparatus can include an uneven outer surface along its longitudinal body through laser ablation of material to form protrusions, forming taper features, forming wave patterns or thread extrusions. ## Claims ### Claim 1 An insertion apparatus for introducing a neurovascular device into a microcatheter via a rotating hemostasis valve (RHV), the insertion apparatus comprising: a longitudinal body defining a lumen therethrough that allows the neurovascular device to pass through, and an uneven outer surface preventing a backward movement of the insertion apparatus from the microcatheter when introducing the neurovascular device into the microcatheter wherein the RHV further comprises: a seal comprising with a recess formed in the seal; and wherein the uneven surface comprises at least one threaded extrusion engaging with the recess formed in the seal of the RHV. ### Claim 2 (depends on 1) The insertion apparatus of claim 1, wherein a distal portion of the longitudinal body comprises a distalmost taper to allow the distal portion to advance partially into the microcatheter. ### Claim 3 (depends on 1) The insertion apparatus of claim 1, wherein the uneven outer surface comprises a sealing relationship with respect to a seal of the RHV. ### Claim 4 (depends on 1) The insertion apparatus of claim 1, wherein the uneven outer surface defines a plurality of tapers along a length of the longitudinal body to reduce movement of the insertion apparatus during introduction of the neurovascular device into the microcatheter. ### Claim 5 (depends on 4) The insertion apparatus of claim 4, wherein the plurality of tapers comprises: a first plurality of tapers inclined in a first direction at a first side of the insertion apparatus, and a second plurality of tapers inclined in a second direction at a second side of the insertion apparatus, the second direction being opposite from the first direction. ### Claim 6 (depends on 1) The insertion apparatus of claim 1, wherein the longitudinal body defines a length in a range from about 410 mm to about 600 mm. ### Claim 7 (depends on 1) The insertion apparatus of claim 1, wherein the threaded extrusion comprises a thickness less than a width of the recess formed in the seal of the RHV. ### Claim 8 (depends on 7) The insertion apparatus of claim 7, wherein the uneven outer surface comprises a plurality of protrusions, and wherein at least one protrusion comprises a length from about 2 mm to about 3 mm. ### Claim 9 (depends on 1) The insertion apparatus of claim 1, wherein the uneven outer surface comprises a knurled surface. ### Claim 10 (depends on 1) The insertion apparatus of claim 1, wherein the uneven outer surface comprises a wave pattern along a length of the longitudinal body, and wherein the RHV further comprises a recess of a seal comprising a complementary profile engaging with the uneven outer surface.