# US 11,992,588 B2 · Blood hose set, a control device or closed-loop control device, a blood treatment apparatus and a method for the single-needle treatment

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- Number: US 11,992,588 B2
- Document ID: US11992588B2
- Status: Granted
- Kind: B2
- Application number: 17/046,069
- Filed: 2019-04-08
- Published: 2021-02-04
- Granted: 2024-05-28
- Earliest claimed: 2018-04-10
- Assignees: Fresenius Medical Care Deutschland GmbH
- Applicants: Fresenius Medical Care Deutschland GmbH
- Inventors: Pascal Kopperschmidt; Christian Schlaeper
- Web page: https://patentgrep.com/patent/US11992588B2

## CPC

- A61M 1/1601: {Control or regulation}
- A61M 1/16: with membranes
- A61M 1/267: {used for pumping}
- A61M 1/30: Single needle dialysis {; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis}
- A61M 1/301: {Details}
- A61M 1/305: {Control of inversion point between collection and re-infusion phase}
- A61M 1/34: Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M 1/3413: {Diafiltration}
- A61M 1/3427: {back through the membrane, e.g. by inverted trans-membrane pressure [TMP]}
- A61M 1/3434: {with pre-dilution and post-dilution}
- A61M 1/3622: {with a cassette forming partially or totally the blood circuit}
- A61M 1/36224: {with sensing means or components thereof}
- A61M 1/36225: {with blood pumping means or components thereof}
- A61M 39/105: {Multi-channel connectors or couplings, e.g. for connecting multi-lumen tubes (multi-channel connectors in general F16L37/56)}
- A61M 39/28: Clamping means for squeezing flexible tubes, e.g. roller clamps {(tube strippers A61M1/83)}
- A61M 1/362262: {Details of incorporated reservoirs}
- A61M 1/362265: {Details of valves}
- A61M 2205/12: with interchangeable cassettes forming partially or totally the fluid circuit
- A61M 2205/3331: Pressure; Flow
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

The present disclosure relates to a blood hose set, or to an extracorporeal blood circuit, for a single-needle treatment. In some embodiments, the set includes: a patient hose line and a Y-shaped connector or three-way connecter, which is connected to the patient hose line. In some embodiments, the blood hose set does not include any single-needle chamber in a blood path or on a blood side, nor is it connected to any single-needle chamber provided in a blood path or on a blood side. The present disclosure further relates to a control device or closed-loop control device, a blood treatment apparatus, a method for the single-needle treatment, a digital storage medium, a computer program product and a computer program.

## Claims

### Claim 1

A control device for control or closed-loop control of a blood treatment apparatus for treatment of blood by a single-needle method, wherein the blood treatment apparatus to be controlled or closed-loop controlled comprises:
a blood pump connectable to a blood hose set for conveying blood through the blood hose set, wherein the blood pump is operable in a withdrawal direction;
a return pump, arranged to convey fluid towards the blood hose set or to a section thereof and/or towards a patient in a return direction during use of the blood treatment apparatus;
wherein the control device is configured to execute a method by using the blood treatment apparatus, the method encompassing the following steps:
a) operating the blood pump in a withdrawal direction in which blood is withdrawn from a patient blood circuit and pumped along a patient hose line into the blood hose set; and
b) operating the return pump such that blood is pumped out of the blood hose set and pumped back along the patient hose line into the patient blood circuit;
wherein:
steps a) and b) are executed several times alternately;
blood is not stored in a single-needle chamber provided in a blood path or on a blood side between its withdrawal in step a) and its return in step b); and
the method executed by the control device is controlled and/or monitored by or based on an analysis of pressure measurement values and/or by or based on a motor current or an electricity consumption of at least one pump.

### Claim 2 (depends on 1)

The control device according to claim 1, wherein the method further encompasses:
closing a venous hose clamp during or prior to conveying blood in step a) from the patient towards a blood filter;
effecting transfer of plasma water of the conveyed blood via a semipermeable membrane of the blood filter by establishing a pressure difference between a dialysis liquid chamber and a blood chamber;
opening the venous hose clamp; and
effecting the transfer of liquid from the dialysis liquid chamber via the semipermeable membrane into the blood chamber of the blood filter by establishing a suitable pressure on a hydraulic side, while in step b) blood is being pumped back into the patient blood circuit along the patient hose line.

### Claim 3 (depends on 1)

The control device according to claim 1, wherein the blood hose set comprises:
the patient hose line for both blood withdrawal from the patient blood circuit into the blood hose set and for blood return from the blood hose set back into the patient blood circuit; and
a Y-shaped connector or three-way connector which is connected to the patient hose line,
wherein the blood hose set comprises in the blood path or on the blood side no single-needle chamber nor is the blood hose set connected to any single-needle chamber provided in the blood path or on the blood side.

### Claim 4

A blood treatment apparatus for executing a single needle blood treatment, wherein the blood treatment apparatus comprises:
a blood pump connectable to a blood hose set for conveying blood through the blood hose set, wherein the blood pump is operable in a withdrawal direction;
a return pump, arranged to convey blood towards the blood hose set or to a section thereof and/or towards a patient in a return direction during use of the blood treatment apparatus;
a control device configured to control or closed loop control the blood treatment apparatus;
wherein:
the control device is programmed to execute the single needle blood treatment by a method encompassing the following steps:
a) operating the blood pump in a withdrawal direction in which blood is withdrawn from a patient blood circuit and pumped into the blood hose set; and
b) operating the return pump such that the blood is pumped out of the blood hose set and pumped back into the patient blood circuit;
wherein the steps a) and b) are executed several times alternately;
blood is not intermediately stored in a single needle chamber provided in a blood path or on a blood side between its withdrawal in step a) and its return in step b); and
the method executed by the control device is controlled and/or monitored by or based on an analysis of pressure measurement values and/or by or based on a motor current or an electricity consumption of at least one pump.

### Claim 5 (depends on 4)

The blood treatment apparatus according to claim 4, wherein the blood treatment apparatus is embodied as a hemodialysis apparatus, a hemofiltration apparatus, a hemodiafiltration apparatus, an apparatus for chronic renal replacement therapy, or an apparatus for continuous renal replacement therapy (CRRT).