# US 11,992,549 B2 · Oil-in-water emulsion

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- Number: US 11,992,549 B2
- Document ID: US11992549B2
- Status: Granted
- Kind: B2
- Application number: 17/250,923
- Filed: 2018-09-27
- Published: 2022-01-13
- Granted: 2024-05-28
- Earliest claimed: 2018-09-27
- Assignees: Wacker Chemie AG
- Applicants: Wacker Chemie AG
- Inventors: Xinyu Liang; Zhiyuan Xu
- Web page: https://patentgrep.com/patent/US11992549B2

## CPC

- A61K 8/898: containing nitrogen, e.g. amodimethicone, trimethyl silyl amodimethicone or dimethicone propyl PG-betaine
- A61K 8/062: {Oil-in-water emulsions}
- A61K 8/39: Derivatives containing from 2 to 10 oxyalkylene groups
- A61K 8/891: saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
- A61K 8/922: {of vegetable origin}
- A61Q 5/00: Preparations for care of the hair
- A61Q 5/02: Preparations for cleaning the hair
- A61Q 19/00: Preparations for care of the skin
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS

## Abstract

An oil-in-water emulsion and a method of preparing the oil-in-water emulsion. The oil-in-water emulsion includes a siloxane mixture, a natural oil, an emulsifier and water.

## Claims

### Claim 1

An oil-in-water emulsion comprising:
(a) a siloxane mixture, comprising (a1) a silicone compound having a dynamic viscosity at 25° C. of from 30,000 to 1,200,000 mPa·s and (a2) an amino-functional silicone having an amine number of from 1 to 50 mgKOH/g;
(b) natural oil;
(c) emulsifier; and
(d) water;
wherein ingredient (a1) is of the following formula:
R1R22SiO(R22SiO)mSiR22R1
wherein R2 is, identically or differently on each occurrence, a monovalent hydrocarbon group having from 1 to 18 carbon atoms;
wherein R1 is, identically or differently on each occurrence, R2, hydroxyl group or a C1-C6alkoxy group;
wherein the mass ratio of ingredient (b) to ingredient (a1) is 5:(4-32); and
wherein the mass ratio of ingredient (b) to ingredient (a2) is 5:(1-8).

### Claim 2 (depends on 1)

The oil-in-water emulsion of claim 1, wherein the mass ratio of ingredient (b) to ingredient (a) is 1:(1-8).

### Claim 3 (depends on 2)

The oil-in-water emulsion of claim 2, wherein the mass ratio of ingredient (b) to ingredient (a) is 1:(2-8).

### Claim 4 (depends on 1)

The oil-in-water emulsion of any one of claim 1, wherein the ingredient (b) is present in an amount of from 5 to 25 wt % based on the total weight of the emulsion.

### Claim 5 (depends on 1)

The oil-in-water emulsion of any one of claim 1, wherein the ingredient (a) is present in an amount of from 20 to 60 wt % based on the total weight of the emulsion.

### Claim 6 (depends on 1)

The oil-in-water emulsion of any one of claim 1, wherein the ingredients (b) and (a) are present in a total amount of from 40 to 70 wt % based on the total weight of the emulsion.

### Claim 7 (depends on 1)

The oil-in-water emulsion of any one of claim 1, wherein the ingredient (b) is an oil derived from vegetables, seeds or nuts.

### Claim 8 (depends on 1)

The oil-in-water emulsion of any one of claim 1, wherein the ingredient (c) comprises one polyoxyethylene alkyl ether or ester having an HLB value of from 5 to 10 and two polyoxyethylene alkyl ethers or esters having an HLB value of from 10 to 20.

### Claim 9 (depends on 8)

The oil-in-water emulsion of claim 8, wherein the ingredient (c) has an HLB value of from 12 to 16.

### Claim 10 (depends on 8)

The oil-in-water emulsion of claim 8, wherein the ingredient (c) is present in an amount of less than 15 wt % based on the total weight of the silicone mixture and natural oil.

### Claim 11 (depends on 1)

The oil-in-water emulsion of any one of claim 1, wherein the ingredient (a1) has a dynamic viscosity at 25° C. of from 40,000 to 100,000 mPa·s.

### Claim 12 (depends on 1)

The oil-in-water emulsion of any one of claim 1, wherein the ingredient (a2) has an amine number of from 5 to 10 mgKOH/g.

### Claim 13

A method for preparing the oil-in-water emulsion, comprising:
providing an oil-in-water emulsion comprising (a) a siloxane mixture, comprising (a1) a silicone compound having a dynamic viscosity at 25° C. of from 30,000 to 1,200,000 mPa·s and (a2) an amino-functional silicone having an amine number of from 1 to 50 mgKOH/g, (b) natural oil, (c) emulsifier, and (d) water, wherein ingredient (a1) is of the formula: R1R22SiO(R22SiO)mSiR22R1, wherein where R2 is, identically or differently on each occurrence, a monovalent hydrocarbon group having from 1 to 18 carbon atoms, wherein R1 is, identically or differently on each occurrence, R2, hydroxyl group or a C1-C6 alkoxy group; and
wherein the mass ratio of ingredient (b) to ingredient (a1) is 5:(4-32);
wherein the mass ratio of ingredient (b) to ingredient (a2) is 5:(1-8); and
wherein the oil-in-water emulsion has a particle size of less than 500 nm.

### Claim 14 (depends on 13)

The method for preparing an oil-in-water emulsion of claim 13, further comprising the following steps of:
1) Mixing the siloxane mixture with the natural oil to obtain a mixed oil;
2) Mixing the emulsifier and the mixed oil to obtain a paste; and
3) adding water to the paste and homogenizing to obtain the product.

### Claim 15 (depends on 13)

The method for preparing an oil-in-water emulsion of claim 13, wherein the oil-in-water emulsion is used in personal care products.

### Claim 16 (depends on 15)

The method for preparing an oil-in-water emulsion of claim 15, wherein the personal care products are rinse-off hair care products.

### Claim 17 (depends on 1)

The oil-in-water emulsion of claim 1, wherein the oil-in-water emulsion is used in personal care products.

### Claim 18 (depends on 17)

The oil-in-water emulsion of claim 17, wherein the personal care products are rinse-off hair care products.