# US 11,992,512 B2 · Composition and method for treating dyspepsia

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- Number: US 11,992,512 B2
- Document ID: US11992512B2
- Status: Granted
- Kind: B2
- Application number: 17/728,564
- Filed: 2022-04-25
- Published: 2022-10-13
- Granted: 2024-05-28
- Earliest claimed: 2018-12-05
- Applicants: Kodimule Shyam Prasad
- Inventors: Kodimule Shyam Prasad
- Web page: https://patentgrep.com/patent/US11992512B2

## CPC

- A61K 36/28: Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K 31/357: having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K 36/23: Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61P 1/14: Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

The invention provides a composition and method for treating dyspepsia with asafoetida and milk thistle extract. A method of making the inventive composition is contemplated.

## Claims

### Claim 1

A composition for promoting digestive health, comprising an effective amount of an extract of Ferula asafoetida and an effective amount of an extract of Silybum marianum containing at least 25% silymarin, wherein said extract of Ferula asafoetida and said extract of Silybum marianum are present in a ratio of about 1:3, respectively.

### Claim 2 (depends on 1)

The composition of claim 1, wherein said extract of Ferula asafoetida comprises oleoresin.

### Claim 3 (depends on 1)

The composition of claim 1, wherein said composition is in a form selected from the group consisting of a powder, liquid, pill, tablet, pellet, capsule, thin film, solution, spray, syrup, linctus, lozenge, pastille, chewing gum, paste, vapor, suspension, emulsion, ointment, cream, lotion, liniment, gel, drop, topical patch, buccal patch, bead, gummy, sol, injection, and combinations thereof.

### Claim 4 (depends on 1)

The composition of claim 1, wherein said composition further comprises at least one of a vitamin, mineral, extract, amino acid, protein, carbohydrate, lipid, fatty acid, food, beverage, nutritional supplement, dietary supplement, excipient, pharmaceutically acceptable carrier, bulking agent, binding agent, caffeine, flavoring, sweetener, and preservative.

### Claim 5 (depends on 1)

The composition of claim 1, wherein said extract of Ferula asafoetida and said extract of Silybum marianum have a total combined dose of between about 250 mg and about 500 mg.

### Claim 6 (depends on 1)

The composition of claim 1, wherein said composition further comprises a controlled-release formulation.

### Claim 7 (depends on 6)

The composition of claim 6, wherein said controlled-release formulation is selected from an osmotic membrane, a polymer and a glycolipid.

### Claim 8 (depends on 7)

The composition of claim 7, wherein said polymer is a swellable polymer or an acrylic polymer.

### Claim 9 (depends on 7)

The composition of claim 7, wherein said polymer is a polymeric matrix.

### Claim 10 (depends on 9)

The composition of claim 9, wherein said polymeric matrix is selected from poly-d,l-lactic acid, poly-L-lactic acid, polyglycolic acid, copolymers of mixed d,l-lactic acid and glycolic acid, copolymers of L-lactic acid and glycolic acid, copolyoxalates, polycaprolactone, poly (lactic acid-caprolactone), poly(glycolic acid-caprolactone), casein and albumin.