# US 11,992,460 B2 · Adapter and injection fluid transfer method

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- Number: US 11,992,460 B2
- Document ID: US11992460B2
- Status: Granted
- Kind: B2
- Application number: 17/282,721
- Filed: 2019-10-03
- Published: 2022-01-06
- Granted: 2024-05-28
- Earliest claimed: 2018-10-04
- Assignees: Daicel Corporation
- Applicants: Daicel Corporation
- Inventors: Yuzo Yamamoto; Takamasa Suzuki
- Web page: https://patentgrep.com/patent/US11992460B2

## CPC

- A61J 1/2048: {Connecting means}
- A61M 5/30: Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
- A61M 5/1782: {Devices aiding filling of syringes in situ (combination of a vial and a syringe for transferring or mixing their contents A61J1/2096, filling of medical containers in general B65B3/003)}
- A61M 5/2046: {Media being expelled from injector by gas generation, e.g. explosive charge}
- A61M 2039/1077: {Adapters, e.g. couplings adapting a connector to one or several other connectors}
- A61M 2209/045: for filling, e.g. for filling reservoirs
- A61J: CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

The adapter includes a housing and a filling nozzle provided in communication with a containing portion in the housing and coming into contact with an end surface of the injection device, in which the injection port of the injection nozzle is formed, when the housing is attached to the injection device. An open end of the filling nozzle is set to be smaller than an inner diameter of the containing portion and larger than the injection port. Of an internal space of the housing from a partial region of the containing portion to the open end, at least a predetermined space being continuous and including the partial region is formed in a manner where an inner diameter of the predetermined space decreases toward a side of the open end. According to this configuration, the injection fluid can be suitably transferred from the outside to a needleless injector.

## Claims

### Claim 1

An adapter for transferring a predetermined injection fluid, via an injection port of an injection nozzle, to an injection device that injects the predetermined injection fluid from the injection nozzle, the adapter comprising:
a housing defining a containing portion containing the predetermined injection fluid to be transferred, the housing being configured to be attachable to and detachable from the injection device; and
a filling nozzle provided in communication with the containing portion in the housing, when the housing is attached to the injection device, the filling nozzle being configured to come into contact with an end surface of the injection device, in which the injection port of the injection nozzle is formed, the filling nozzle being configured to allow the predetermined injection fluid contained in the containing portion to flow to a side of the injection nozzle, an open end of the filling nozzle being set to be smaller than an inner diameter of the containing portion and larger than the injection port of the injection nozzle,
wherein
the filling nozzle includes a protruding portion having an annular shape and protruding from the filling nozzle toward a distal end side of the adapter, the protruding portion is formed in a manner where, when the housing is attached to the injection device, a distal end of the protruding portion comes into contact with the end surface of the injection device,
wherein
of an internal space of the housing from a partial region of the containing portion to the open end of the filling nozzle, at least a predetermined space inside the protruding portion is formed in a manner where an inner diameter of the predetermined space decreases toward a side of the open end of the filling nozzle.

### Claim 2 (depends on 1)

The adapter according to claim 1, wherein
the predetermined space is a space including all of the internal space of the partial region and the filling nozzle, and
from the partial region to the open end of the filling nozzle, the predetermined space is formed in a manner where the inner diameter of the predetermined space decreases continuously toward the side of the open end of the filling nozzle.

### Claim 3 (depends on 1)

The adapter according to claim 1, wherein
the protruding portion is formed of a flexible member.

### Claim 4 (depends on 1)

The adapter according to claim 1, wherein
the injection device includes a nozzle portion having a cylindrical shape and internally including the injection nozzle, the nozzle portion being formed exposing the injection port of the injection nozzle at an end surface of the nozzle portion, and
the housing includes a first cylindrical portion provided surrounding the filling nozzle, in the housing, the first cylindrical portion being in a fitted state with an outer peripheral wall surface of the nozzle portion when the housing is attached to the injection device.

### Claim 5 (depends on 4)

The adapter according to claim 4, wherein
the outer peripheral wall surface of the nozzle portion forms a tapered surface inclined along an axial direction of the nozzle portion, and
when the housing is attached to the injection device, an inner wall surface of the first cylindrical portion is in the fitted state while pressing the outer peripheral wall surface of the nozzle portion.

### Claim 6 (depends on 4)

The adapter according to claim 4, further comprising:
a holding portion configured to hold the fitted state between the first cylindrical portion and the outer peripheral wall surface of the nozzle portion when the housing is attached to the injection device.

### Claim 7 (depends on 4)

The adapter according to claim 4, wherein
the housing includes a second cylindrical portion provided surrounding the first cylindrical portion, in the housing, the second cylindrical portion being in a fitted state with an outer peripheral wall surface of the injection device when the housing is attached to the injection device.

### Claim 8

An injection fluid transfer method comprising:
preparing an adapter for transferring a predetermined injection fluid, via an injection port of an injection nozzle, to an injection device that injects the predetermined injection fluid from the injection nozzle, the adapter including a housing defining a containing portion containing the predetermined injection fluid to be transferred and a filling nozzle connected to the containing portion in the housing, an open end of the filling nozzle being set to be smaller than an inner diameter of the containing portion and larger than the injection port of the injection nozzle, the filling nozzle including a protruding portion having an annular shape and protruding from the filling nozzle toward a distal end side of the adapter, the protruding portion being formed in a manner where, when the housing is attached to the injection device, a distal end of the protruding portion comes into contact with the end surface of the injection device, of an internal space of the housing from a partial region of the containing portion connected to the filling nozzle to the open end of the filling nozzle, at least a predetermined space inside the protruding portion being formed in a manner where an inner diameter of the predetermined space decreases toward a side of the open end of the filling nozzle;
attaching the housing to the injection device and causing a distal end of the filling nozzle to be in contact with an end surface of the injection device, in which the injection port of the injection nozzle is formed;
pouring the predetermined injection fluid into the containing portion; and
transferring the predetermined injection fluid from the containing portion to the injection device in a state where the adapter is positioned above the injection device in a vertical direction.