# US 11,992,325 B2 · Systems, devices and methods for dextrous hand function assessment and therapy > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,992,325 B2 - Document ID: US11992325B2 - Status: Granted - Kind: B2 - Application number: 17/102,457 - Filed: 2020-11-24 - Published: 2022-05-26 - Granted: 2024-05-28 - Earliest claimed: 2019-11-22 - Assignees: Mindmaze Group SA - Applicants: Mindmaze Group SA - Inventors: Naveed Ejaz; Nicolas Fremaux; Sylvain Cardin; Mouna Cerra Cheraka; Gangadhar Garipelli - Web page: https://patentgrep.com/patent/US11992325B2 ## CPC - A61B 5/4076: {Diagnosing or monitoring particular conditions of the nervous system} - A61B 5/0002: {Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network (endoradiosondes A61B5/07)} - A61B 5/11: Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb {(A61B5/1038 takes precedence; motion detection to correct for motion artifacts in physiological signals A61B5/721)} - A61B 5/1125: {Grasping motions of hands} - A61B 5/225: {of the fingers, e.g. by monitoring hand-grip force} - A61B 5/4836: {Diagnosis combined with treatment in closed-loop systems or methods (A61B5/0036 takes precedence)} - A61B 5/6825: {Hand} - A61B 5/742: {using visual displays (displays for heart-related electrical signals, e.g. ECG, A61B5/339)} - A61B 2562/0219: Inertial sensors, e.g. accelerometers, gyroscopes, tilt switches - A61B 2562/0247: Pressure sensors - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract Devices, methods and systems related to the assessment and therapy of neurological conditions and dexterous hand function in particular. For example, some embodiments can relate to devices comprising a first portion of flexible material and forming a cavity; a second portion non-flexible material; a PCB coupled to the second portion; and wherein a portion of an edge of the first portion is configured to create a semi-hermetic seal with at least a portion of an edge of the second portion and the PCB has connected thereto a pressure sensor, a wireless transceiver, and a power storage unit. ## Claims ### Claim 1 A device for providing dexterous hand function assessment and therapy, comprising: a first portion of flexible material forming a cavity; a second portion of non-flexible material; a pressure sensor; a wireless transceiver; a power storage unit; a sensor device; a printed circuit board (PCB) coupled to the second portion; and wherein a portion of an edge of the first portion is configured to create a semi-hermetic seal with at least a portion of an edge of the second portion, and the PCB has connected thereto the pressure sensor, the wireless transceiver, and the power storage unit; wherein said pressure sensor comprises a barometer for measuring pressure within said cavity; wherein a temperature reading from said sensor device is provided from within said cavity to form temperature data; wherein said temperature data and said pressure data are transmitted from the device through said wireless transceiver, for determination of an external force applied to said first portion of flexible material. ### Claim 2 (depends on 1) The device of claim 1, further comprising a valve through the second portion and wherein the second portion includes a flat facet. ### Claim 3 (depends on 2) The device of claim 2, further comprising one or more inertial measurement units (IMU) and a memory storage device. ### Claim 4 (depends on 3) The device of claim 3, wherein the first portion comprises a graphical component to enable position and orientation tracking of the device. ### Claim 5 (depends on 3) The device of claim 3, further comprising an active marker to enable position and orientation tracking of the device. ### Claim 6 (depends on 5) The device of claim 5, further comprising a third portion through which the active marker is visible. ### Claim 7 (depends on 1) A method for the assessment and therapy of dexterous hand function, comprising: establishing a connection with the hand device of claim 1; establishing a hand selection assigned to the hand device; receiving a first barometric pressure of the interior of the hand device; sending an instruction to an idle pressure controller indicating the barometric pressure is a baseline. ### Claim 8 (depends on 7) The device of claim 7, further comprising a valve through the second portion; wherein said valve allows air pressure on an interior of the device to adjust to equilibrium with ambient air pressure. ### Claim 9 (depends on 8) The device of claim 8, further comprising a reset button to place pressure on said valve to adjust said air pressure. ### Claim 10 (depends on 8) The device of claim 8, wherein the second portion includes a flat facet, located at a bottom of the device; wherein said non-flexible material of said second portion does not deform under the weight of the device when the device is resting on said flat surface. ### Claim 11 (depends on 1) The device of claim 1, wherein said temperature data and said pressure data are transmitted for calibrating the device for being manually manipulated. ### Claim 12 (depends on 11) The device of claim 11, wherein a force exerted upon said first portion of flexible material upon manual manipulation is determined according to said temperature data and said pressure data. ### Claim 13 (depends on 1) The device of claim 1, wherein said second portion comprises a stationary and non-deformable anchor point, and wherein said PCB is anchored to said anchor point. ### Claim 14 (depends on 7) The device of claim 7, wherein said wireless transmission comprises at least one of Bluetooth, cellular data, or RFID. ### Claim 15 A system for providing dexterous hand function assessment and therapy, comprising: a device for providing dexterous hand function assessment and therapy, comprising: a first portion of flexible material forming a cavity; a second portion of non-flexible material; a printed circuit board (PCB) coupled to the second portion; a pressure sensor; a wireless transceiver; a power storage unit; a sensor device; and wherein a portion of an edge of the first portion is configured to create a semi-hermetic seal with at least a portion of an edge of the second portion, and the PCB has connected thereto the pressure sensor, the wireless transceiver, and the power storage unit; wherein said pressure sensor comprises a barometer for measuring pressure within said cavity; a base station comprising a battery charging component, the battery charging component including a cooling system; and the system further comprising an external computational device; wherein a temperature reading from said sensor device is provided from within said cavity to form temperature data: wherein the pressure within the device is determined according to said barometer sensor data from said pressure sensor and said temperature data; and wherein an applied force to the device is determined by said external computational device according to the pressure and the temperature data. ### Claim 16 (depends on 15) The system of claim 15, wherein calibration data is received by said external computational device, said calibration data comprising a first barometric pressure of the interior of the device; wherein said first barometric pressure is a baseline. ### Claim 17 (depends on 16) The system of claim 16, wherein a calibration process is performed with a user manipulating the device, wherein said calibration process further comprises performing a plurality of manipulations of the device, comprising a movement of the device and a grip on the device, to determine at least one of user range of motion, a maximum pressure for gestures, a minimum acceleration, a maximum acceleration, or a combination thereof. ### Claim 18 (depends on 17) The system of claim 17, wherein said user range of motion is determined from accelerometer data. ### Claim 19 (depends on 18) The system of claim 18, wherein said user range of motion comprises wrist flexion/extension, and wherein a range of motion of wrist flexion/extension is determined by deriving a first plane from an acceleration vector when the device is held by the user at maximum wrist flexion, and by deriving a second plane when the device is held by the user at maximum wrist extension; wherein said range of motion is determined according to an angle between these two vectors on the plane. ### Claim 20 (depends on 19) The system of claim 19, wherein said wireless transmission comprises at least one of Bluetooth, cellular data, or RFID. ### Claim 21 (depends on 20) The system of claim 20 wherein the device comprises a processor for operating firmware, wherein said firmware controls a connection between the device and said external computational device, for streaming data from the device to said external computational device. ### Claim 22 (depends on 21) The system of claim 21, wherein said streaming data is streamed as packets, according to one or more streaming data parameters to select and configure packet content, comprising one or more of timestamp data, acceleration data, gyroscope data, barometer data, temperature data, pressure/force normalization data, or quaternion data, or a combination thereof. ### Claim 23 (depends on 22) The system of claim 22, wherein said accelerometer data is processed through a signal processing to dampen a signal from said accelerometer with minimal impact on latency for use during calibration and activity use.