# US 11,992,303 B2 · Electrode array for physiological monitoring and device including or utilizing same > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,992,303 B2 - Document ID: US11992303B2 - Status: Granted - Kind: B2 - Application number: 18/158,063 - Filed: 2023-01-23 - Published: 2023-05-25 - Granted: 2024-05-28 - Earliest claimed: 2015-01-08 - Assignees: Medasense Biometrics Ltd. - Applicants: Medasense Biometrics Ltd. - Inventors: Galit Zuckerman-Stark; Nir Ben-Israel; Noam Racheli; Aviad Yeshaya; Aviem Amossi - Web page: https://patentgrep.com/patent/US11992303B2 ## CPC - A61B 5/0533: Measuring galvanic skin response - A61B 5/02055: {Simultaneously evaluating both cardiovascular condition and temperature} - A61B 5/4824: {Touch or pain perception evaluation (A61B5/4821 takes precedence)} - A61B 5/6826: {Finger} - A61B 5/6831: {Straps, bands or harnesses} - A61B 5/6834: {using vacuum} - A61B 3/112: {for measuring diameter of pupils} - A61B 5/0075: {by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy (A61B5/0071 takes precedence)} - A61B 5/021: Measuring pressure in heart or blood vessels - A61B 5/0285: Measuring or recording phase velocity of blood waves - A61B 5/0816: {Measuring devices for examining respiratory frequency (measuring frequency of electric signals G01R23/00)} - A61B 5/103: Measuring devices for testing the shape, pattern, {colour,} size or movement of the body or parts thereof, for diagnostic purposes (measuring instruments specially adapted for dentistry A61C19/04) - A61B 2560/0223: of calibration, e.g. protocols for calibrating sensors - A61B 2560/0252: using ambient temperature - A61B 2562/0204: Acoustic sensors - A61B 2562/0219: Inertial sensors, e.g. accelerometers, gyroscopes, tilt switches - A61B 2562/043: in a linear array - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract Electrode array for monitoring of physiological parameters and devices including or utilizing same, the electrode array including an active electrode configured to provide an electrical signal and at least two inactive electrodes configured to collect the electrical signal transferred from the active electrode, wherein each of the at least two inactive electrodes are positioned at a different predetermined distance from the active electrode. ## Claims ### Claim 1 A galvanic skin response (GSR) electrode array comprising: a scaffold configured for attachment along a length of a subject's finger, the scaffold comprising: at least one active electrode configured to provide an electrical signal to at least two measurement electrodes, wherein the active electrode is an electrode configured to continuously receive an applied electrical signal, at least two measurement electrodes, each configured to simultaneously collect the electrical signal transferred from the active electrode along the subject's skin, wherein each of the at least two measurement electrodes configured to be positioned at a different predetermined distance from the active electrode based on attachment along the length of the subject's finger. ### Claim 2 (depends on 1) The GSR electrode array of claim 1, further comprising a connection point enabling transmittal of the electrical signal collected by each of the at least two measurement electrodes. ### Claim 3 (depends on 1) The GSR electrode array of claim 1, wherein the active electrode comprises a hydrogel configured to mediate contact between the active electrode and the subject's skin and wherein each of the at least two measurement electrodes comprise a hydrogel configured to mediate contact between the measurement electrode and the subject's skin. ### Claim 4 (depends on 1) The GSR electrode array of claim 1, wherein a distance between the active electrode and a first of the at least two measurement electrodes is different than a distance between the active electrode and a second of the at least two measurement electrodes. ### Claim 5 (depends on 1) The GSR electrode array of claim 1, wherein the at least two measurement electrodes are identical. ### Claim 6 (depends on 1) The GSR electrode array of claim 1, wherein the at least two measurement electrodes are made from a different material. ### Claim 7 (depends on 1) The GSR electrode array of claim 1, wherein the at least two measurement electrodes have a different size and/or shape. ### Claim 8 (depends on 1) The GSR electrode array of claim 1, further comprising at least one sensor selected from the group consisting of: a PPG sensor, an accelerometer, a temperature sensor, a diffused correlation spectroscopy (DCS) sensor, an acoustics sensor, a bio-impedance sensor, a piezoelectric sensor, and any combination thereof. ### Claim 9 (depends on 1) The GSR electrode array of claim 1, wherein the scaffold comprises at least one element selected from the group consisting of: a resistor, a capacitor, a solenoid, a diode, and any combination thereof. ### Claim 10 (depends on 1) The GSR electrode array of claim 1, wherein each of the at least one active electrodes is configured to receive an alternating current (AC) of different frequencies. ### Claim 11 (depends on 1) A method for determining electrical conductance of a subject's skin, the method comprising: receiving electrical signals from the measurement electrodes of a GSR electrode array of claim 1; determining a preferred measurement electrode among the plurality of measurement electrodes based on the received electrical signal; and determining the electrical conductance of the subject's skin based on an integrated analysis of an electrical signal received from the preferred measurement electrode and on a distance between the active electrode and the preferred measurement electrode. ### Claim 12 (depends on 11) The method of claim 11, wherein the electrical conductance of the subject's skin comprises providing a weight factor to the received electrical signal, wherein the weight factor is based on a distance between the active electrode and the measurement electrode determined as producing an optimal signal. ### Claim 13 (depends on 11) The method of claim 11, further comprising measuring a change in the electrical conductance of the subject's skin based on a change in an electrical signal obtained during a first measurement and a second measurement of the signal obtained from the measurement electrode determined as producing an optimal signal. ### Claim 14 (depends on 1) A method for determining a value of a physiological parameter, the method comprising: applying an alternating current (AC) excitation at different frequencies to at least one active electrode; measuring a first electrical signal obtained from a first measurement electrode of the GSR electrode array of claim 1 after a first predetermined time; measuring a second electrical signal obtained from a second measurement electrode after a second predetermined time; and determining the value of the physiological parameter based on the first electrical signal and the second electrical signal. ### Claim 15 (depends on 14) The method of claim 14, wherein the physiological parameter is a hemodynamic parameter selected from the group consisting of: blood flow, heart rate, pulse transient time (PTT), and any combination thereof. ### Claim 16 (depends on 14) The method of claim 14, wherein the physiological parameter is a respiration parameter selected from the group consisting of: a respiration rate, apnea, fast/slow changes in the respiration, and any combination thereof. ### Claim 17 (depends on 14) The method of claim 14, wherein determining the value of the physiological parameter further comprises obtaining at least one signal from: a PPG sensor, a piezoelectric sensor, a diffused correlation spectroscopy (DCS) sensor, an acoustics sensor, a bio-impedance sensor, a temperature sensor, or any combination thereof. ### Claim 18 A probe, comprising: at least one sensor selected from the group consisting of: a photoplethysmograph (PPG) sensor, an accelerometer, a temperature sensor, a diffused correlation spectroscopy (DCS) sensor, an acoustics sensor, a bio-impedance sensor, a piezoelectric sensor, and any combination thereof; and a connection point connectable to a GSR electrode array comprising: a scaffold configured for attachment to a subject's skin, the scaffold comprising: at least one active electrode configured to provide an electrical signal to at least two measurement electrodes, wherein the active electrode is an electrode configured to continuously receive an applied electrical signal, at least two measurement electrodes, each configured to simultaneously collect the electrical signal transferred from the active electrode along the subject's skin, wherein each of the at least two measurement electrodes configured to be positioned at a different predetermined distance from the active electrode based on attachment to the subject's skin. ### Claim 19 (depends on 18) The probe of claim 18, wherein when the GSR electrode array is electrically connected to the connection point, the at least one sensor is activated. ### Claim 20 (depends on 18) The probe of claim 18, wherein the probe comprises at least two sensors. ### Claim 21 (depends on 20) The probe of claim 20 wherein the at least two sensors are selected from the group consisting of: a PPG sensor, a piezoelectric sensor, a diffused correlation spectroscopy (DCS) sensor, and any combination thereof.