# US 11,992,265 B2 · Ophthalmologic information analysis apparatus and ophthalmologic information analysis program

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- Number: US 11,992,265 B2
- Document ID: US11992265B2
- Status: Granted
- Kind: B2
- Application number: 17/366,809
- Filed: 2021-07-02
- Published: 2022-01-06
- Granted: 2024-05-28
- Earliest claimed: 2020-07-03
- Assignees: Nidek Co., Ltd.
- Applicants: Nidek Co., Ltd.
- Inventors: Ryosuke Shiba; Tetsuya Kano; Yukihiro Higuchi
- Web page: https://patentgrep.com/patent/US11992265B2

## CPC

- A61B 3/102: {for optical coherence tomography [OCT]}
- G06T 7/0016: {involving temporal comparison}
- A61B 3/0058: {for multiple images}
- G06T 7/0012: {Biomedical image inspection}
- G06T 7/33: using feature-based methods
- G06T 2207/10101: Optical tomography; Optical coherence tomography [OCT]
- G06T 2207/30041: Eye; Retina; Ophthalmic
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL

## Abstract

There are provided an ophthalmologic information analysis apparatus and an ophthalmologic information analysis program capable of efficiently performing follow-up observation of a subject eye. There is provided: a central processing unit configured to: acquire first analysis data obtained by analyzing an analysis region of the subject eye in first OCT data including the analysis region; acquire second OCT data captured on a day different from that of the first OCT data; perform an analysis comprising: specifying the analysis region corresponding to the first analysis data from the second OCT data; and acquiring second analysis data obtained by analyzing the analysis region in the second OCT data; and control a display to display the first analysis data and the second analysis data in a comparable manner.

## Claims

### Claim 1

An ophthalmologic information analysis apparatus for analyzing OCT data captured by scanning a subject eye with measurement light by an optical coherence tomography, the apparatus comprising:
a display; and
a central processing unit configured to:
acquire first analysis data obtained by analyzing an analysis region of the subject eye in first OCT data including the analysis region, the analysis region being obtained by scanning the measurement light in a transverse direction in a first scanning range on the subject eye;
acquire second OCT data captured on a day different from that of the first OCT data, the second OCT data including at least the analysis region obtained by scanning the measurement light in the transverse direction in a second scanning range different from the first scanning range on the subject eye;
perform an analysis comprising:
specifying the analysis region corresponding to the first analysis data from the second OCT data; and
acquiring second analysis data obtained by analyzing the analysis region in the second OCT data, regardless of a difference between the first scanning range and the second scanning range; and
control the display to display the first analysis data and the second analysis data in a comparable manner,
wherein the first OCT data is a plurality of pieces of data including data including a first analysis region as the analysis region and data including a second analysis region different from the first analysis region as the analysis region, in which the first scanning ranges are different from each other,
wherein the central processing unit is configured to:
acquire the first analysis data obtained by analyzing the first analysis region and the second analysis region in the acquiring of the first analysis data;
acquire the second OCT data including both the first analysis region and the second analysis region as the analysis region in the acquiring of the second OCT data; and
specify at least one of the first analysis region and the second analysis region corresponding to the first analysis data from the second OCT data, and acquire the second analysis data obtained by analyzing at least one of the first analysis region and the second analysis region in the second OCT data in the performing of the analysis.

### Claim 2 (depends on 1)

The ophthalmologic information analysis apparatus according to claim 1, the central processing unit further configured to set the analysis region analyzed in the performing of the analysis,
wherein in the performing of the analysis, the central processing unit is configured to selectively analyze any of the first analysis region or the second analysis region based on the analysis region set in the setting.

### Claim 3 (depends on 1)

The ophthalmologic information analysis apparatus according to claim 1,
wherein in the performing of the analysis, the central processing unit is configured to acquire follow-up observation data for observing a progress of the analysis region in the subject eye, and
wherein in the controlling of the display, the central processing unit is configured to display the follow-up observation data on the display.

### Claim 4 (depends on 1)

The ophthalmologic information analysis apparatus according to claim 1,
wherein in the controlling of the display, the central processing unit is configured to set analysis data in which the analysis regions in the subject eye at least partially overlap as a target, and display the analysis data on the display in a comparable manner.

### Claim 5 (depends on 1)

The ophthalmologic information analysis apparatus according to claim 1, wherein the first analysis region is macula, and the second analysis region is optic papilla.

### Claim 6

An ophthalmologic information analysis apparatus for analyzing OCT data captured by scanning a subject eye with measurement light by an optical coherence tomography, the apparatus comprising:
a display; and
a central processing unit configured to:
acquire first analysis data obtained by analyzing an analysis region of the subject eye in first OCT data including the analysis region, the analysis region being obtained by scanning the measurement light in a transverse direction in a first scanning range on the subject eye;
acquire second OCT data captured on a day different from that of the first OCT data, the second OCT data including at least the analysis region obtained by scanning the measurement light in the transverse direction in a second scanning range different from the first scanning range on the subject eye;
perform an analysis comprising:
specifying the analysis region corresponding to the first analysis data from the second OCT data; and
acquiring second analysis data obtained by analyzing the analysis region in the second OCT data, regardless of a difference between the first scanning range and the second scanning range; and
control the display to display the first analysis data and the second analysis data in a comparable manner,
acquire third OCT data including the analysis region, which is obtained by scanning the measurement light in the second scanning range on the subject eye being captured on a day different from that of the first OCT data and the second OCT data,
wherein in the performing of the analysis, the central processing unit is configured to specify the analysis region corresponding to the first analysis data or the second analysis data from the third OCT data, and acquires third analysis data obtained by analyzing the analysis region in the third OCT data, and
wherein in the controlling of the display, the central processing unit is configured to display at least one of the first analysis data and the second analysis data, and the third analysis data on the display unit in a comparable manner.

### Claim 7 (depends on 6)

The ophthalmologic information analysis apparatus according to claim 6,
wherein in the performing of the analysis, the central processing unit is configured to specify the first analysis region corresponding to the first analysis data or the second analysis data from the third OCT data, and acquires the third analysis data obtained by analyzing the first analysis region in the third OCT data.

### Claim 8 (depends on 6)

The ophthalmologic information analysis apparatus according to claim 6,
wherein in the performing of the analysis, the central processing unit is configured to specify the second analysis region corresponding to the first analysis data or the second analysis data from the third OCT data, and acquire the third analysis data obtained by analyzing the second analysis region in the third OCT data.

### Claim 9 (depends on 6)

The ophthalmologic information analysis apparatus according to claim 6, wherein in the performing of the analysis, the central processing unit is configured to acquire follow-up observation data for observing a progress of the analysis region in the subject eye, and
wherein in the controlling of the display, the central processing unit is configured to display the follow-up observation data on the display.

### Claim 10 (depends on 6)

The ophthalmologic information analysis apparatus according to claim 6, wherein in the controlling of the display, the central processing unit is configured to set analysis data in which the analysis regions in the subject eye at least partially overlap as a target, and display the analysis data on the display in a comparable manner.

### Claim 11

A non-transitory computer-readable storage medium storing a program executed by a processor of an ophthalmologic information analysis apparatus for analyzing OCT data captured by scanning a subject eye with measurement light by an optical coherence tomography, the program, when executed by the processor, causing the ophthalmologic information analysis apparatus to perform:
acquiring first analysis data obtained by analyzing an analysis region of the subject eye in first OCT data including the analysis region, which is obtained by scanning the measurement light in a transverse direction in a first scanning range on the subject eye;
acquiring second OCT data including at least the analysis region, which is obtained by scanning the measurement light in the transverse direction in a second scanning range different from the first scanning range on the subject eye being captured on a day different from that of the first OCT data;
an analysis comprising:
specifying the analysis region corresponding to the first analysis data from the second OCT data; and
acquiring second analysis data obtained by analyzing the analysis region in the second OCT data, regardless of a difference between the first scanning range and the second scanning range; and
controlling a display to display the first analysis data and the second analysis data in a comparable manner,
wherein the first OCT data is a plurality of pieces of data including data including a first analysis region as the analysis region and data including a second analysis region different from the first analysis region as the analysis region, in which the first scanning ranges are different from each other,
wherein the central processing unit is configured to:
acquire the first analysis data obtained by analyzing the first analysis region and the second analysis region in the acquiring of the first analysis data;
acquire the second OCT data including both the first analysis region and the second analysis region as the analysis region in the acquiring of the second OCT data; and
specify at least one of the first analysis region and the second analysis region corresponding to the first analysis data from the second OCT data, and acquire the second analysis data obtained by analyzing at least one of the first analysis region and the second analysis region in the second OCT data in the performing of the analysis.
