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US 11,987,607 B2Granted
Antimicrobial peptides with alpha-core helices
AssigneeLundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
InventorsNannette Y. Yount, Michael R. Yeaman
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Abstract
Computational systems and methods are described for identifying new α-helical antimicrobial peptides using a systemic consensus formula. Newly identified α-helical antimicrobial peptides are tested experimentally and show potent microbiocidal activities.
Claims8
A method for treating an infection in a patient in need thereof, comprising administering to the patient a polypeptide comprising the amino acid sequence of SEQ ID NO:
- 3, wherein the peptide is not longer than 60 amino acid residues in length.
Dependencies are inferred from the claim text.