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US 11,980,410 B2Granted
Composite scaffolds for thermal ablation of metastatic cancer cells
AssigneeRegents of the University of Minnesota
InventorsSamira M. Azarin, Francisco Pelaez, Navid Manuchehrabadi, John C. Bischof
Life of this patent
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Abstract
A device includes an electrically conductive or electrically semiconductive material and a biocompatible porous scaffold around the electrically conductive or electrically semiconductive material. The biocompatible porous scaffold includes a biocompatible polymer and pores configured to capture metastatic cells.
Claims14
A method, comprising:
- applying, by an electromagnetic source, an electromagnetic induction stimulus to an implantable device implanted in a body of a patient at a target strength and target frequency for a target duration,
- wherein the implantable device comprises:
- an electrically conductive or electrically semiconductive material comprising a plurality of particles;
- and
- a biocompatible porous scaffold around the electrically conductive or electrically semiconductive material,
- wherein the biocompatible porous scaffold comprises a biocompatible polymer and pores configured to capture metastatic cells,
- wherein the plurality of particles is disposed in the biocompatible polymer substantially throughout a volume of the biocompatible porous scaffold, and
- wherein the electromagnetic induction stimulus is selected to cause the electrically conductive or electrically semiconductive material to heat at least a portion of the biocompatible porous scaffold to at least a target temperature.
5 more elements
A device, comprising:
- an implantable device, comprising:
- an electrically conductive or electrically semiconductive material comprising a plurality of particles;
- and
- a biocompatible porous scaffold around the electrically conductive or electrically semiconductive material;
- and
- an electromagnetic source configured to apply an electromagnetic induction stimulus to the implantable device at a target strength and target frequency for a target duration,
- wherein the biocompatible porous scaffold comprises a biocompatible polymer and pores configured to capture metastatic cells,
- wherein the plurality of particles is disposed in the biocompatible polymer substantially throughout a volume of the biocompatible porous scaffold, and
- wherein the electromagnetic induction stimulus is configured to cause the electrically conductive or electrically semiconductive material to heat at least a portion of the biocompatible porous scaffold to at least a target temperature.
6 more elements
Dependencies are inferred from the claim text.