Blood plasma product

A spray dried plasma made from donor plasma, said spray dried plasma comprising:

• a) dried plasma particles having a size ranging from about 1 to about 7 μm;
• b) when reconstituted, a reduced mean size of particulates when measured with a Coulter Multisizer 4 by the electrical sensing zone method for particulates having a size range from about 2 μm to 60 μm, as compared to the mean size of particulates in the donor plasma;
• c) when reconstituted has a reduced number of cholesterol crystals, when viewed at 100× magnification, as compared to reconstituted freeze dried plasma;
• d) residual moisture in a range from about 0.5% to about 2.5%;
• e) stable when stored for a period of time ranging from about 1 day to about 48 months at a temperature ranging from about 1° C. to about 45° C., as compared to reconstituted spray dried plasma before storage;
• f) when reconstituted, is stable for transfusion, after storage for up to 8 hours;
• g) when reconstituted with Sterile Water For Injection (SWFI) has a pH ranging from about 6.7 to about 7.8;
• and
• h) when reconstituted, has an amount of von Willebrand Ristocetin Cofactor (VWF:RCo) ranging from about 10 to about 200 IU/dL, or and amount of von Willebrand Factor Antigen (VWF:Ag) ranging from about 50 to 200 IU/dL
• wherein, when the spray dried plasma is reconstituted to thereby obtain reconstituted spray dried plasma, the reconstituted spray dried plasma allows for clot formation.