Process for preparing 2-methyl-N-(2′-methylbutyl)butanamide
AssigneeShin-Etsu Chemical Co., Ltd.
InventorsTakeshi Kinsho, Yusuke Nagae, Shogo Tsukaguchi, Yasuhiko Kutsuwada, Tatsuya Hojo, Takeru Watanabe
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AssigneeShin-Etsu Chemical Co., Ltd.
InventorsTakeshi Kinsho, Yusuke Nagae, Shogo Tsukaguchi, Yasuhiko Kutsuwada, Tatsuya Hojo, Takeru Watanabe
Estimating the term…
The present invention provides a process for preparing 2-methyl-N-(2′-methylbutyl)butanamide of the following formula (1): the process comprising: subjecting an α-arylethyl-2-methylbutylamine compound of the following general formula (2): wherein Ar represents a substituted or unsubstituted aryl group having 6 to 20 carbon atoms, to N-2-methylbutyrylation to form an N-α-arylethyl-2-methyl-N-(2′-methylbutyl)butanamide compound of the following general formula (3): wherein Ar is as defined above, and removing the α-arylethyl group of the resulting compound (3) to form 2-methyl-N-(2′-methylbutyl)butanamide (1).
A process for preparing a mixture of diastereomers of general formulae (2R*,αR*)-(2) and (2S*,αR*)-(2) of an α-arylethylamine compound:
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