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US 11,969,482 B2Granted
Resorbable implant material made from magnesium or a magnesium alloy
AssigneeHelmholtz-Zentrum hereon GmbH
InventorHajo Dieringa
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AssigneeHelmholtz-Zentrum hereon GmbH
InventorHajo Dieringa
Estimating the term…
The present invention relates to a resorbable implant material made of magnesium or magnesium alloy and to a process for the production thereof. A disadvantage of the known resorbable implants is that their resorption has hitherto only been trackable using x-ray or CT examinations. The invention provides a resorbable implant material comprising homogeneously distributed fluorescent nanodiamonds in a matrix of magnesium or a magnesium alloy. Fluorescent nanodiamonds are biologically nonhazardous and provide a stable emission in the near infrared range due to nitrogen-vacancy centers (NV centres). This allows detection of the implant material in the blood plasma of the patient. The resorbable implant material according to the invention is produced by a process wherein magnesium or a magnesium alloy is melted, nanodiamonds are added to the melt and the melt of magnesium or a magnesium alloy provided with nanodiamonds is subjected to an ultrasound treatment.
An implant material comprising homogeneously distributed fluorescent nanodiamonds having nitrogen-vacancy centers in a matrix of magnesium or a magnesium alloy, wherein the fluorescent nanodiamonds have nitrogen-vacancy centers (NV centers) which after excitation by a 532 nm laser beam have a detectable fluorescence band centered at a wavelength between 650 nm and 700 nm.
A method for determining the degree of resorption of an implant material in a patient comprising detecting a fluorescence signal in the patient's blood, wherein the implant material comprises homogeneously distributed fluorescent nanodiamonds having nitrogen-vacancy centers in a matrix of magnesium or a magnesium alloy, wherein the fluorescent nanodiamonds have nitrogen-vacancy centres (NV centers) which after excitation by a 532 nm laser beam have a detectable fluorescence band centered at a wavelength between 650 nm and 700 nm.
A method of treating fractures or stenoses, wherein an implant material comprising homogeneously distributed fluorescent nanodiamonds having nitrogen-vacancy centers in a matrix of magnesium or magnesium alloy is implanted in the body of a patient in need thereof,
Dependencies are inferred from the claim text.