Pharmaceutical compositions and related methods of delivery
AssigneeAmryt Endo, Inc.
InventorsRoni Mamluk, Moshe Tzabari, Karen Marom, Paul Salama, Irina Weinstein
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Abstract
The pharmaceutical compositions described herein include a suspension which comprises an admixture in solid form of a therapeutically effective amount of a therapeutic agent and at least one salt of a medium chain fatty acid and a hydrophobic medium, e.g. castor oil or glyceryl tricaprylate or a mixture thereof. The pharmaceutical compositions described herein contain medium chain fatty acid salts and are substantially free of alcohols. The pharmaceutical compositions may be encapsulated in a capsule. Methods of treating or preventing diseases by administering such compositions to affected subjects are also disclosed.
Claims18
An oral dosage form, comprising:
- a composition comprising a suspension which comprises an admixture of a hydrophobic medium and a solid form,
- wherein the solid form comprises:
- a therapeutically effective amount of octreotide and a medium chain fatty acid salt, wherein the composition comprises 12% to 21% by weight of the medium chain fatty acid salt, and at least 3% by weight of a matrix forming polymer.
Dependencies are inferred from the claim text.