Compositions and methods for treating the eye

A microemulsion composition for treating the eye comprising:

• i) a safe and effective amount of a compound and/or extract having retinol-like properties and/or benefits for use in treating the eye selected from one or more of:
• botanical extracts from plants of the genus Acronychia, Licaria, Calendula and/or Trigonella;
• bacterial extracts of the genus Actinomyces;
• and compounds of Formula (I):
• wherein—
• the dotted lines represent simple or double bound;
• optionally one of the dotted line is a double bound;
• R1 represent an H, a carbonated chain, linear, cyclic, or branched, saturated or unsaturated, comprising from 1 to 20 carbon atoms;
• R2 represent a carbonated chain, linear, cyclic ringed, or branched, saturated or unsaturated, comprising from 1 to 20 carbon atoms;
• optionally a methyl (—CH3) or methylene (═CH2) moiety;
• a carbonated chain, linear, ringed, or branched, saturated or unsaturated, comprising from 1 to 20 carbon atoms;
• optionally from 1 to 10 carbon atoms;
• optionally 6 carbon atoms;
• optionally an aromatic moiety, optionally a phenyl moiety;
• optionally 2-methyl-prop-1,3-diene;
• ii) an ophthalmologically acceptable carrier,
• wherein the microemulsion droplets or particles have a maximum dimension of less than 1,500 Å.