Inhibitor of indoleamine-2,3-dioxygenase (IDO)

A method of treating a disease associated with IDO, the method comprising administering to a subject in need thereof an effective amount of a compound of Formula (I):

• or a pharmaceutically acceptable salt thereof,
• wherein:
• W is a bond;
• Q is —C(═O)NH— or a bond;
• Y is —CR8═ or —N═;
• R1 is —C(═O)OH, —C(═O)OR10, substituted or unsubstituted heterocyclyl, substituted or unsubstituted heteroaryl, —NHSO2R9, —C(═O)NHSO2R9, —C(═O)NHC(═O)OR10, or —SO2NHC(═O)R10;
• R2 and R3 are each independently hydrogen, halogen, substituted or unsubstituted C1-C6 alkyl, substituted or unsubstituted C1-C6 alkoxy, or R2 and R3 are joined to form a substituted or unsubstituted 3- to 8-membered carbocyclic ring, or substituted or unsubstituted 3- to 8-membered heterocyclic ring;
• R4 and R5 are each independently hydrogen, substituted or unsubstituted C1-C6 alkyl, substituted or unsubstituted C2-C6 alkenyl, substituted or unsubstituted C5-C8 cycloalkenyl, substituted or unsubstituted C2-C10 alkynyl, substituted or unsubstituted C1-C6 alkoxy, substituted or unsubstituted C3-C8 cycloalkyl, substituted or unsubstituted 3- to 12-membered heterocyclyl, substituted or unsubstituted 5- to 6-membered monocyclic heteroaryl, substituted or unsubstituted 8- to 10-membered bicyclic heteroaryl, substituted or unsubstituted aryl, or arylsulfonyl;
• or R4 and R5 are joined together with the N they are attached to form optionally substituted, monocyclic or bicyclic, heterocyclyl;
• R6 is substituted or unsubstituted C1-C6 alkyl, substituted or unsubstituted C3-C8 cycloalkyl;
• substituted or unsubstituted C2-C6 alkenyl, substituted or unsubstituted C2-C6 alkynyl, substituted or unsubstituted C5-C8 cycloalkenyl, substituted or unsubstituted aryl, substituted or unsubstituted 4- to 7-membered monocyclic heterocyclyl, substituted or unsubstituted 7- to 10-membered bicyclic heterocyclyl, substituted or unsubstituted 5- to 6-membered monocyclic heteroaryl, substituted or unsubstituted 8- to 10-membered bicyclic heteroaryl, substituted or unsubstituted C1-C6 alkoxy, substituted or unsubstituted aryloxy, or —C(═O)R7;
• R7 is hydrogen, substituted or unsubstituted C1-C6 alkyl, or substituted or unsubstituted aryl;
• R8 is hydrogen, halogen, —CN, —OH, substituted or unsubstituted C1-C6 alkyl, or substituted or unsubstituted C1-C6 alkoxy;
• and
• R9 and R10 are each independently hydrogen, substituted or unsubstituted C1-C6 alkyl, or substituted or unsubstituted C2-C6 alkenyl.