Methods, compositions, and devices for making sustained biodegradable implants in tissue
AssigneePathak Holdings LLC
InventorChandrashekhar P. Pathak
Life of this patent
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Abstract
This invention discloses methods and composition to form biodegradable polymer implant arrays in the live tissue. Artificial cavities are created in the live tissue by using laser ablation, oscillating needle, microneedle array and other methods. The cavities are then filled with biodegradable polymer solution. The solvent in the polymer solution is dissipated in the tissue to form a biodegradable polymer implant in artificial cavities. The cavities and implants formed are arranged to form of an array of implants. The biodegradable polymer in the cavity can also be loaded with drug to form biodegradable drug delivery array in the live tissue.
Claims21
A method of making a sustained biodegradable implant in a tissue, the method comprising:
- creating a plurality of artificial cavities of predetermined shape and volume in the tissue;
- filling the plurality of artificial cavities partially or completely with an injectable liquid polymeric implant-forming composition selected from a cross-linkable composition, thermoreversible composition, or neat liquid carrier composition;
- and
- forming the sustained biodegradable implant in the plurality of artificial cavities from the implant-forming composition.
Dependencies are inferred from the claim text.