Implants for bone and cartilage repair

A biocompatible and bioresorbable implant having a physically and mechanically stable bi-phasic structure for the repair of bone and cartilage, comprising a cell conductive zone that contains a first matrix including first biopolymeric fibers, and an osteoconductive zone that contains a second matrix including second biopolymeric fibers and calcium-containing mineral particles, the osteoconductive zone having a top, a bottom, and sides therebetween, wherein the first biopolymeric fibers in the first matrix are derived from tendon or dermis, the cell conductive zone is free of calcium-containing mineral particles, the first biopolymeric fibers extend into the osteoconductive zone and overlap with the second biopolymeric fibers such that the cell conductive zone and the osteoconductive zone are physically and mechanically integrated, the cell conductive zone overlaps with and is in direct contact with the osteoconductive zone, the cell conductive zone covering the top and sides of the osteoconductive zone leaving the bottom of the osteoconductive zone exposed, the first biopolymeric fibers and the second biopolymeric fibers at a surface of the implant are oriented along a plane of the surface, and the first biopolymeric fibers and the second biopolymeric fibers located greater than 2 mm from the surface are randomly oriented.