Use of stereoselective transaminase in asymmetric synthesis of chiral amine
AssigneeAbiochem Biotechnology Co., Ltd.
InventorsZhanbing Cheng, Tao Zhang, Zhenhua Tian, Shaonan Ding
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AssigneeAbiochem Biotechnology Co., Ltd.
InventorsZhanbing Cheng, Tao Zhang, Zhenhua Tian, Shaonan Ding
Estimating the term…
Use of a stereoselective transaminase in the asymmetric synthesis of a chiral amine. In particular, provided is use of a polypeptide in the production of a chiral amine or a downstream product using a chiral amine as a precursor. Further provided is a method for producing a chiral amine, comprising culturing a strain expressing the polypeptide so as to obtain a chiral amine. Further provided are novel prochiral compounds, a chiral amine production strain and a method for constructing the chiral amine production strain. The stereoselective transaminase has a broad substrate spectrum and thus has a broad application potential in the preparation of a chiral amine.
A compound of Formula II, a pharmaceutically acceptable salt thereof, or a stereoisomer thereof:
Dependencies are inferred from the claim text.